POLR2E [nucleoplasm]

Stable Identifier
R-HSA-83713
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
nucleoplasm
Synonyms
HsRPABC1, DNA-directed RNA polymerase II 23 kDa polypeptide (EC 2.7.7.6) (RPB25) (XAP4) (RPB5), DNA-directed RNA polymerase II 23 kDa polypeptide , RPB25, XAP4, RPB5, RPABC1
Locations in the PathwayBrowser
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External Reference Information
External Reference
UniProt:P19388 POLR2E
Gene Names
POLR2E
Chain
chain:1-210
Reference Genes
BioGPS Gene:5434 POLR2E
COSMIC (genes):POLR2E POLR2E
CTD Gene:5434 POLR2E
dbSNP Gene:5434 POLR2E
ENSEMBL:ENSG00000099817 POLR2E
HGNC:9192 POLR2E
KEGG:hsa:5434 POLR2E
Monarch:5434 POLR2E
NCBI Gene:5434 POLR2E
OMIM:180664 POLR2E
UCSC:P19388 POLR2E
Reference Transcript
Other Identifiers
11716271_at
11716272_a_at
11716273_x_at
11750008_a_at
11750009_x_at
16866565
213887_PM_s_at
213887_s_at
217854_PM_s_at
217854_s_at
3348058
3348070
3844953
3844954
3844955
3844956
3844957
3844958
3844959
3844960
3844961
3844962
3844963
3844964
3844965
3844966
3844968
3844969
3844970
3844971
3844972
3844973
3844974
3844975
41332_at
5434
8032149
84752_r_at
A_23_P165280
A_33_P3299829
A_33_P3299834
D38251_s_at
GO:0000428
GO:0001054
GO:0001055
GO:0001056
GO:0003677
GO:0003824
GO:0003899
GO:0005515
GO:0005634
GO:0005654
GO:0005665
GO:0005666
GO:0005730
GO:0005736
GO:0005829
GO:0006351
GO:0006360
GO:0006362
GO:0006366
GO:0006383
GO:0006399
GO:0016740
GO:0042797
GO:0043226
GO:0050821
GO:0140098
GO:1990062
HMNXSV003026961
Hs.24301.1.S1_3p_a_at
PH_hs_0031090
RNA95124|RNS_206_189
TC19000996.hg
Participates
as a component of
as an input of
Other forms of this molecule
POLR2E [cytosol]
Inferred To
polr2eb [nucleoplasm] (Danio rerio)
Polr2E [nucleoplasm] (Drosophila melanogaster)
rpb5 [nucleoplasm] (Schizosaccharomyces pombe)
RPB5 [nucleoplasm] (Saccharomyces cerevisiae)
polr2e [nucleoplasm] (Dictyostelium discoideum)
polr2e [nucleoplasm] (Xenopus tropicalis)
Polr2e [nucleoplasm] (Mus musculus)
Polr2e [nucleoplasm] (Rattus norvegicus)
POLR2E [nucleoplasm] (Bos taurus)
POLR2E [nucleoplasm] (Canis familiaris)
POLR2E [nucleoplasm] (Gallus gallus)
POLR2E [nucleoplasm] (Plasmodium falciparum)
POLR2E [nucleoplasm] (Sus scrofa)
rpb-5 [nucleoplasm] (Caenorhabditis elegans)
Cross References
OpenTargets
ENSEMBL
GeneCards
HPA
PRO
Pharos - Targets
GlyGen
HMDB Protein
PDB
Interactors (92)
Accession #Entities Entities Confidence Score Evidence (IntAct)
 UniProt:P62875 POLR2L  2 0.867 9
 UniProt:P61218 POLR2F  2 0.867 11
 UniProt:P62487 POLR2G  1 0.841 8
 UniProt:O95602 POLR1A  1 0.837 6
 UniProt:Q9Y2Y1 POLR3K  2 0.825 6
 UniProt:Q9NW08 POLR3B  2 0.825 7
 UniProt:O14802 POLR3A  2 0.825 7
 UniProt:P05423 POLR3D  2 0.825 8
 UniProt:Q9NVU0 POLR3E  2 0.825 7
 UniProt:P62136 PPP1CA  1 0.807 6
 UniProt:O94763 RMP      0.802 5
 UniProt:O15514 POLR2D  1 0.793 7
 UniProt:P24928 POLR2A  7 0.793 7
 UniProt:Q9H1D9 POLR3F  2 0.775 6
 UniProt:Q9BUI4 POLR3C  2 0.775 6
 UniProt:O15318 POLR3G  2 0.775 6
 UniProt:O15160 POLR1C  2 0.775 7
 UniProt:Q9Y535 POLR3H  2 0.775 6
 UniProt:P52434 POLR2H  2 0.772 7
 UniProt:P53803 POLR2K  2 0.772 7
 UniProt:Q9GZS1 POLR1E  1 0.744 5
 UniProt:Q00403 GTF2B  1 0.736 6
 UniProt:P19387 POLR2C  1 0.731 7
 UniProt:P52435 POLR2J  1 0.731 8
 UniProt:P36954 POLR2I  1 0.731 6
 UniProt:Q9UBK9 UXT  1 0.725 5
 UniProt:P19784 CSNK2A2  2 0.725 4
 UniProt:A0JLT2 MED19  1 0.725 4
 UniProt:Q9H6T3 RPAP3      0.725 4
 UniProt:Q9NWS0 PIHD1      0.725 5
 UniProt:P0DPB6 RPAC2      0.71 5
 UniProt:O75575 CRCP  2 0.71 4
 UniProt:P30876 POLR2B  1 0.648 5
 UniProt:Q9NQG5 RPRD1B  1 0.643 3
 UniProt:Q9BTT4 MED10  1 0.643 3
 UniProt:Q9NWA0 MED9  1 0.643 3
 UniProt:Q8IXW5 RPAP2  1 0.643 4
 UniProt:Q9H9Y6 POLR1B  1 0.643 4
 UniProt:Q9UHV9 PFDN2  1 0.643 3
 UniProt:O15446 POLR1G  1 0.643 3
 UniProt:O95402 MED26  1 0.643 5
 UniProt:Q9HCN4 GPN1      0.643 3
 UniProt:Q7KZ85 SUPT6H  1 0.643 3
 UniProt:O43156 TTI1      0.597 4
 UniProt:P36873 PPP1CC  1 0.569 3
 UniProt:P22607 FGFR3  20 0.556 3
 UniProt:Q9Y649 Q9Y649      0.556 3
 UniProt:Q9UMX0 UBQLN1  1 0.556 3
 UniProt:P02489 CRYAA      0.556 3
 UniProt:Q14957 GRIN2C  3 0.556 3
 IntAct:EBI-25847655 CCSB      0.556 3
 UniProt:Q01658 DR1  1 0.556 3
 UniProt:Q9Y5Q9 GTF3C3  1 0.556 3
 UniProt:Q14204 DYNC1H1  3 0.556 3
 UniProt:Q86V38 Q86V38      0.556 3
 UniProt:P00488 F13A1  4 0.556 3
 UniProt:Q9Y2X8 UBE2D4  1 0.556 3
 UniProt:Q96PC2 IP6K3  1 0.556 6
 UniProt:Q92876 KLK6      0.556 3
 UniProt:P20226 TBP  1 0.528 3
 UniProt:P35269 GTF2F1  1 0.528 3
 UniProt:P13984 GTF2F2  1 0.528 3
 UniProt:Q9Y3C7 MED31  1 0.527 2
 UniProt:P68400 CSNK2A1  2 0.527 2
 UniProt:P67870 CSNK2B  5 0.527 2
 UniProt:Q9BT43 POLR3GL  2 0.527 2
 UniProt:Q6P2C8 MED27  1 0.527 2
 UniProt:Q6VAB6 KSR2  1 0.527 6
 UniProt:Q9NPJ6 MED4  1 0.527 2
 UniProt:Q9H204 MED28  1 0.527 2
 UniProt:O94762 RECQ5      0.527 2
 UniProt:O75586 MED6  1 0.527 2
 UniProt:Q13503 MED21  1 0.527 2
 UniProt:O15212 PFDN6  1 0.527 3
 UniProt:Q96HR3 MED30  1 0.527 2
 UniProt:Q9NUG6 PDRG1      0.527 2
 UniProt:P0CAP2 GRL1A      0.527 2
 UniProt:P0CAP1 MYZAP      0.527 2
 UniProt:Q8NG08 HELB      0.527 2
 UniProt:Q9UHW5 GPN3      0.527 2
 UniProt:Q96MX6 DAA10      0.527 2
 UniProt:Q9Y265 RUVBL1  1 0.527 5
 UniProt:Q9NX70 MED29  1 0.527 2
 UniProt:O60244 MED14  1 0.527 2
 UniProt:Q9BUE0 MED18  1 0.527 2
 UniProt:Q9Y230 RUVBL2  1 0.527 3
 UniProt:Q9NVC6 MED17  1 0.527 2
 UniProt:Q9P1U0 POLR1H  1 0.527 2
 UniProt:O00267 SUPT5H  1 0.527 3
 UniProt:P07900 HSP90AA1  8 0.527 3
 UniProt:P62140 PPP1CB  4 0.508 2
 UniProt:Q15435 PP1R7      0.508 2
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