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POLR2F [nucleoplasm]
Stable Identifier
R-HSA-83714
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
nucleoplasm
Synonyms
HsRPABC2, DNA-directed RNA polymerase II 14.4 kDa polypeptide (EC 2.7.7.6) (RPB6) (RPB14.4), DNA-directed RNA polymerase II 14.4 kDa polypeptide , RPB6, RPB14.4, RPABC2
Locations in the PathwayBrowser for interactor UniProt:Q8N7H5 PAF1
Expand all
Gene expression (Transcription) (Homo sapiens)
RNA Polymerase I Transcription (Homo sapiens)
RNA Polymerase I Promoter Clearance (Homo sapiens)
RNA Polymerase I Transcription Initiation (Homo sapiens)
Assembly of RNA Polymerase I Holoenzyme (human) (Homo sapiens)
POLR2F [nucleoplasm] (Homo sapiens)
External Reference Information
External Reference
UniProt:P61218 POLR2F
Gene Names
POLR2F, POLRF
Chain
initiator methionine:, chain:2-127
Reference Genes
BioGPS Gene:5435 POLR2F
COSMIC (genes):POLR2F POLR2F
CTD Gene:5435 POLR2F
dbSNP Gene:5435 POLR2F
ENSEMBL:ENSG00000100142 POLR2F
ENSEMBL_homo_sapiens_GENE:ENSG00000100142.16 POLR2F
HGNC:9193 POLR2F
KEGG Gene (Homo sapiens):5435 POLR2F
Monarch:5435 POLR2F
NCBI Gene:5435 POLR2F
OMIM:604414 POLR2F
UCSC:P61218 POLR2F
Reference Transcript
RefSeq:NM_021974.4 POLR2F
Other Identifiers
11720324_a_at
11720325_at
209511_PM_at
209511_at
36027_at
3945134
3945136
3945138
3945141
3945143
3945144
3945145
5435
8072979
A_24_P417007
A_33_P3318960
GO:0000428
GO:0001054
GO:0001055
GO:0001056
GO:0001650
GO:0003677
GO:0003824
GO:0003899
GO:0005634
GO:0005654
GO:0005665
GO:0005666
GO:0005730
GO:0005736
GO:0005829
GO:0006351
GO:0006360
GO:0006366
GO:0006399
GO:0016740
GO:0042797
GO:0043226
GO:0140098
HMNXSV003017910
PH_hs_0003285
Z27113_at
g13097770_3p_at
g13097770_3p_x_at
Participates
as a component of
RNA Polymerase III Holoenzyme [nucleoplasm] (Homo sapiens)
RNA Polymerase I Holoenzyme [nucleoplasm] (Homo sapiens)
RNA Polymerase II holoenzyme complex (p-Ser2,7 CTD) [nucleoplasm] (Homo sapiens)
RNA Polymerase II holoenzyme complex (p-Ser5,7 CTD) [nucleoplasm] (Homo sapiens)
RNA Polymerase II holoenzyme complex (hypophosphorylated):TFIIF complex [nucleoplasm] (Homo sapiens)
RNA Polymerase II holoenzyme complex (phosphorylated) [nucleoplasm] (Homo sapiens)
Ubiquitinated RNA Polymerase II holoenzyme complex (hyperphosphorylated) [nucleoplasm] (Homo sapiens)
RNA Polymerase II holoenzyme complex phosphorylated by CDK12 [nucleoplasm] (Homo sapiens)
RNA Polymerase II holoenzyme complex (hyperphosphorylated) [nucleoplasm] (Homo sapiens)
RNA Polymerase II holoenzyme complex (unphosphorylated) [nucleoplasm] (Homo sapiens)
RNA Polymerase II holoenzyme complex (generic) [nucleoplasm] (Homo sapiens)
as an input of
Assembly of RNA Polymerase I Holoenzyme (human) (Homo sapiens)
Other forms of this molecule
POLR2F [cytosol]
Inferred To
polr2f [nucleoplasm]
(Danio rerio)
polr2f [nucleoplasm]
(Dictyostelium discoideum)
polr2f [nucleoplasm]
(Xenopus tropicalis)
Ghost homologue of POLR2F [nucleoplasm]
(Canis familiaris)
RPO26 [nucleoplasm]
(Saccharomyces cerevisiae)
Polr2F [nucleoplasm]
(Drosophila melanogaster)
rpb6 [nucleoplasm]
(Schizosaccharomyces pombe)
rpb-6 [nucleoplasm]
(Caenorhabditis elegans)
RPB6 [nucleoplasm]
(Gallus gallus)
POLR2F [nucleoplasm]
(Bos taurus)
POLR2F [nucleoplasm]
(Plasmodium falciparum)
POLR2F [nucleoplasm]
(Sus scrofa)
Polr2f [nucleoplasm]
(Mus musculus)
Polr2f [nucleoplasm]
(Rattus norvegicus)
Cross References
RefSeq
NP_068809.1
OpenTargets
ENSG00000100142
GeneCards
P61218
HPA
ENSG00000100142-POLR2F
Ensembl
ENSP00000403852
,
ENSG00000100142
,
ENST00000442738
PRO
P61218
Pharos - Targets
P61218
HMDB Protein
HMDBP11912
PDB
7DU2
,
8IUH
,
5IYA
,
7VBB
,
7VBC
,
7AEA
,
7DTI
,
7DTH
,
6XRE
,
5IY9
,
5IY8
,
7AE3
,
6O9L
,
8A43
,
7OB9
,
5IY7
,
7LBM
,
7A6H
,
7AE1
,
5IY6
,
7DN3
,
7OBA
,
8ITY
,
7D59
,
6DRD
,
7FJJ
,
5IYC
,
7OBB
,
7D58
,
5IYD
,
7AST
,
7VBA
,
7FJI
,
5IYB
,
8IUE
,
1QKL
Interactors (42)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:P19388 POLR2E
2
POLR2E [nucleoplasm]
(R-HSA-83713)
POLR2E [cytosol]
(R-HSA-1964438)
0.867
11
UniProt:P62487 POLR2G
1
POLR2G [nucleoplasm]
(R-HSA-63517)
0.643
5
UniProt:Q9NW08 POLR3B
2
POLR3B [cytosol]
(R-HSA-1964435)
POLR3B [nucleoplasm]
(R-HSA-83702)
0.643
6
UniProt:P24928 POLR2A
7
p-S2,S7(CTD)-POLR2A [nucleoplasm]
(R-HSA-6814543)
p-S5,S7(CTD)-POLR2A [nucleoplasm]
(R-HSA-6810226)
p-S5(CTD)-POLR2A [nucleoplasm]
(R-HSA-77100)
Ub,p-S2,S5(CTD)-POLR2A [nucleoplasm]
(R-HSA-6781855)
p-3S-POLR2A [nucleoplasm]
(R-HSA-6797701)
p-S2,S5(CTD)-POLR2A [nucleoplasm]
(R-HSA-113420)
POLR2A [nucleoplasm]
(R-HSA-63502)
0.643
5
UniProt:P36954 POLR2I
1
POLR2I [nucleoplasm]
(R-HSA-63525)
0.643
5
UniProt:Q9BT43 POLR3GL
2
POLR3GL [nucleoplasm]
(R-HSA-1964458)
POLR3GL [cytosol]
(R-HSA-1964463)
0.643
5
UniProt:O75575 CRCP
2
CRCP [nucleoplasm]
(R-HSA-5420844)
CRCP [cytosol]
(R-HSA-5420849)
0.643
5
UniProt:P52435 POLR2J
1
POLR2J [nucleoplasm]
(R-HSA-63531)
0.643
6
UniProt:O95602 POLR1A
1
POLR1A [nucleoplasm]
(R-HSA-63494)
0.643
6
UniProt:P19387 POLR2C
1
POLR2C [nucleoplasm]
(R-HSA-63506)
0.643
5
UniProt:Q9NVU0 POLR3E
2
POLR3E [nucleoplasm]
(R-HSA-83706)
POLR3E [cytosol]
(R-HSA-1964451)
0.643
6
UniProt:O15446 POLR1G
1
CD3EAP [nucleoplasm]
(R-HSA-5419289)
0.643
5
UniProt:P05423 POLR3D
2
POLR3D [nucleoplasm]
(R-HSA-83704)
POLR3D [cytosol]
(R-HSA-1964429)
0.643
5
UniProt:Q9Y2Y1 POLR3K
2
POLR3K [nucleoplasm]
(R-HSA-1964461)
POLR3K [cytosol]
(R-HSA-1964455)
0.643
5
UniProt:O15160 POLR1C
2
POLR1C [nucleoplasm]
(R-HSA-63498)
POLR1C [cytosol]
(R-HSA-1964454)
0.643
6
UniProt:Q9Y535 POLR3H
2
POLR3H [nucleoplasm]
(R-HSA-83710)
POLR3H [cytosol]
(R-HSA-1964440)
0.643
5
UniProt:O15514 POLR2D
1
POLR2D [nucleoplasm]
(R-HSA-63508)
0.643
5
UniProt:O14802 POLR3A
2
POLR3A [cytosol]
(R-HSA-1964433)
POLR3A [nucleoplasm]
(R-HSA-83700)
0.643
5
UniProt:Q9BUI4 POLR3C
2
POLR3C [cytosol]
(R-HSA-1964448)
POLR3C [nucleoplasm]
(R-HSA-1964430)
0.643
5
UniProt:P0DPB6 RPAC2
0.643
4
UniProt:Q9H1D9 POLR3F
2
POLR3F [cytosol]
(R-HSA-1964434)
POLR3F [nucleoplasm]
(R-HSA-83708)
0.643
6
UniProt:Q9H9Y6 POLR1B
1
POLR1B [nucleoplasm]
(R-HSA-63496)
0.643
5
UniProt:Q8WV16 DCAF4
1
DCAF4 [nucleoplasm]
(R-HSA-8955191)
0.527
3
UniProt:Q00403 GTF2B
1
GTF2B [nucleoplasm]
(R-HSA-65888)
0.527
2
UniProt:P35269 GTF2F1
1
GTF2F1 [nucleoplasm]
(R-HSA-65565)
0.527
2
UniProt:Q9NQG5 RPRD1B
1
RPRD1B [nucleoplasm]
(R-HSA-6814894)
0.527
4
UniProt:Q9UHW5 GPN3
0.527
2
UniProt:P30876 POLR2B
1
POLR2B [nucleoplasm]
(R-HSA-63504)
0.527
4
UniProt:Q7KZ85 SUPT6H
1
SUPT6H [nucleoplasm]
(R-HSA-8932908)
0.527
3
UniProt:P52434 POLR2H
2
POLR2H [nucleoplasm]
(R-HSA-63523)
POLR2H [cytosol]
(R-HSA-1964450)
0.527
4
UniProt:P62875 POLR2L
2
POLR2L [nucleoplasm]
(R-HSA-83715)
POLR2L [cytosol]
(R-HSA-1964467)
0.527
4
UniProt:Q9Y5B0 CTDP1
1
CTDP1 [nucleoplasm]
(R-HSA-113416)
0.527
2
UniProt:Q9GZS1 POLR1E
1
POLR1E [nucleoplasm]
(R-HSA-5419294)
0.527
5
UniProt:Q8N7H5 PAF1
1
PAF1 [nucleoplasm]
(R-HSA-8866689)
0.527
2
UniProt:O94762 RECQ5
0.527
4
UniProt:Q8IXW5 RPAP2
1
RPAP2 [nucleoplasm]
(R-HSA-6810227)
0.527
4
UniProt:Q9HCN4 GPN1
0.527
4
UniProt:O15318 POLR3G
2
POLR3G [nucleoplasm]
(R-HSA-1964459)
POLR3G [cytosol]
(R-HSA-1964446)
0.527
4
UniProt:A0JLT2 MED19
1
MED19 [nucleoplasm]
(R-HSA-556819)
0.527
2
UniProt:Q9P1U0 POLR1H
1
ZNRD1 [nucleoplasm]
(R-HSA-5419292)
0.527
2
UniProt:O00267 SUPT5H
1
p-SUPT5H [nucleoplasm]
(R-HSA-3009372)
0.527
2
UniProt:O95402 MED26
1
MED26 [nucleoplasm]
(R-HSA-556783)
0.527
3
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