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ZNF143 [nucleoplasm]
Stable Identifier
R-HSA-83837
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
nucleoplasm
Synonyms
Staf (SPH-binding factor), Zinc finger protein 143, SPH-binding factor
Locations in the PathwayBrowser for interactor UniProt:Q6MZP7 LIN54
Expand all
Gene expression (Transcription) (Homo sapiens)
RNA Polymerase II Transcription (Homo sapiens)
RNA polymerase II transcribes snRNA genes (Homo sapiens)
POU2F1 (OCT1) or POU2F2 (OCT2), SP1, and ZNF143 (STAF) bind the DSE of snRNA gene (U1, U2, U4, U4atac, U5, U11, U12) (Homo sapiens)
ZNF143 [nucleoplasm] (Homo sapiens)
RNA Polymerase III Transcription (Homo sapiens)
RNA Polymerase III Transcription Initiation (Homo sapiens)
RNA Polymerase III Transcription Initiation From Type 3 Promoter (Homo sapiens)
Binding of SNAPc, Oct-1, and Staf to Type 3 Promoter (Homo sapiens)
ZNF143 [nucleoplasm] (Homo sapiens)
External Reference Information
External Reference
UniProt:P52747 ZNF143
Gene Names
ZNF143, SBF, STAF
Chain
chain:1-638
Reference Genes
BioGPS Gene:7702 ZNF143
COSMIC (genes):ZNF143 ZNF143
CTD Gene:7702 ZNF143
dbSNP Gene:7702 ZNF143
ENSEMBL:ENSG00000166478 ZNF143
HGNC:12928 ZNF143
KEGG:hsa:7702 ZNF143
Monarch:7702 ZNF143
NCBI Gene:7702 ZNF143
OMIM:603433 ZNF143
UCSC:P52747 ZNF143
Reference Transcript
RefSeq:XM_017018254.1 ZNF143
RefSeq:NM_001282657.1 ZNF143
RefSeq:XM_017018255.1 ZNF143
RefSeq:XM_011520349.2 ZNF143
RefSeq:NM_001282656.1 ZNF143
RefSeq:NM_003442.5 ZNF143
Other Identifiers
11743150_s_at
16721809
221873_PM_at
221873_at
31890_s_at
3319894
3319895
3319896
3319897
3319899
3319903
3319904
3319905
3319907
3319908
3319909
3319910
3319911
3319912
3319913
3319914
3319915
3319916
3319917
3319918
3319919
3319920
3319921
3319922
3319923
3319924
3319925
54408_at
7702
7938331
A_14_P108605
A_23_P203564
A_24_P206736
GE62455
GO:0000978
GO:0000981
GO:0001228
GO:0003677
GO:0003682
GO:0005515
GO:0005634
GO:0005654
GO:0006355
GO:0006357
GO:0006359
GO:0043226
GO:0045944
GO:0045945
GO:0046872
GO:0048661
GO:0140110
GO:1905382
HMNXSV003037226
Hs.154095.1.A1_3p_at
ILMN_1674399
PH_hs_0018130
TC11000173.hg
Participates
as an input of
Binding of SNAPc, Oct-1, and Staf to Type 3 Promoter (Homo sapiens)
POU2F1 (OCT1) or POU2F2 (OCT2), SP1, and ZNF143 (STAF) bind the DSE of snRNA gene (U1, U2, U4, U4atac, U5, U11, U12) (Homo sapiens)
as a component of
SNAPc:Oct-1:Staf:Type 3 Promoter Complex [nucleoplasm] (Homo sapiens)
RNA Polymerase III:TFIIIB:SNAPc:Type 3 Open Promoter Complex [nucleoplasm] (Homo sapiens)
POU2F1,2:SP1:ZNF143:snRNA gene [nucleoplasm] (Homo sapiens)
Inferred To
znf143a [nucleoplasm]
(Danio rerio)
ZNF143 [nucleoplasm]
(Bos taurus)
ZNF143 [nucleoplasm]
(Canis familiaris)
ZNF143 [nucleoplasm]
(Gallus gallus)
Ghost homologue of ZNF143 [nucleoplasm]
(Caenorhabditis elegans)
Ghost homologue of ZNF143 [nucleoplasm]
(Dictyostelium discoideum)
Ghost homologue of ZNF143 [nucleoplasm]
(Drosophila melanogaster)
Ghost homologue of ZNF143 [nucleoplasm]
(Mus musculus)
Ghost homologue of ZNF143 [nucleoplasm]
(Rattus norvegicus)
Ghost homologue of ZNF143 [nucleoplasm]
(Saccharomyces cerevisiae)
Ghost homologue of ZNF143 [nucleoplasm]
(Schizosaccharomyces pombe)
Ghost homologue of ZNF143 [nucleoplasm]
(Sus scrofa)
Ghost homologue of ZNF143 [nucleoplasm]
(Xenopus tropicalis)
Cross References
OpenTargets
ENSG00000166478
ENSEMBL
ENSP00000379849
,
ENST00000396602
,
ENST00000530463
,
ENSP00000379847
,
ENST00000396597
,
ENSP00000379843
,
ENSP00000432154
,
ENST00000396604
HPA
ENSG00000166478-ZNF143
PRO
P52747
Pharos - Targets
P52747
GlyGen
P52747
Interactors (20)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:Q14192 FHL2
1
FHL2 [nucleoplasm]
(R-HSA-561161)
0.666
4
UniProt:Q96JC9 EAF1
1
EAF1 [nucleoplasm]
(R-HSA-8932787)
0.556
3
UniProt:Q86YD7 F90A1
0.556
3
UniProt:Q7Z4V0 ZN438
0.556
3
UniProt:Q9NYJ8 TAB2
4
TAB2 [cytosol]
(R-HSA-168117)
TAB2 [endosome membrane]
(R-HSA-450279)
TAB2 [plasma membrane]
(R-HSA-168116)
TAB2 [nucleoplasm]
(R-HSA-1253323)
0.556
3
UniProt:Q14005-2 Q140052
0.556
3
UniProt:P25800 LMO1
1
LMO1 [nucleoplasm]
(R-HSA-8956514)
0.556
3
UniProt:Q8TAP4-4 LMO3
0.556
3
UniProt:Q8NA54 IQUB
0.556
3
UniProt:Q5MJ09 SPXN3
0.556
3
UniProt:P51687 SUOX
1
SUOX [mitochondrial matrix]
(R-HSA-1614570)
0.556
3
UniProt:Q6MZP7 LIN54
1
LIN54 [nucleoplasm]
(R-HSA-389103)
0.556
3
UniProt:Q9Y4C2-2 TCAF1
0.556
3
UniProt:Q9BW85 YJU2
1
YJU2 [nucleoplasm]
(R-HSA-9770430)
0.556
3
UniProt:Q9BRQ3 NUD22
0.556
3
UniProt:Q7Z3K3 POGZ
0.556
3
UniProt:Q9Y3B2 EXOSC1
2
EXOSC1 [nucleoplasm]
(R-HSA-6791578)
EXOSC1 [cytosol]
(R-HSA-429841)
0.556
3
UniProt:Q9H0I2 ENKD1
0.556
3
UniProt:P14678-2 SNRPB
0.556
3
UniProt:Q96KM6 ZNF512B
1
ZNF512B [cytosol]
(R-HSA-9715175)
0.556
3
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