ATP binds to P2X7

Stable Identifier
R-HSA-877178
Type
Reaction [binding]
Species
Homo sapiens
Compartment
extracellular region, plasma membrane
ReviewStatus
5/5
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ATP binds to P2X7
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P2X7 is a receptor for extracellular ATP that acts as a ligand gated non-selective cation channel. It is also responsible for the ATP-dependent lysis of macrophages, which it brings about by mediating the formation of membrane pores permeable to large molecules (Adinolfi et al. 2005).
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Inferred From
ATP binds to p2x7 (Rattus norvegicus)
Authored
Jupe, S  (2010-04-22)
Reviewed
Kufer, TA  (2011-04-28)
Rittinger, K  (2011-06-06)
Wong, E  (2011-06-06)
Created
Jupe, S  (2010-06-11)
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