Toggle navigation
About
What is Reactome ?
News
Team
Scientific Advisory Board
Funding
Editorial Calendar
Release Calendar
Statistics
Our Logo
License Agreement
Privacy Notice
Disclaimer
Digital Preservation
Contact us
Content
Table of Contents
DOIs
Data Schema
Reactome Research Spotlight
ORCID Integration Project
COVID-19 Disease Pathways
Docs
Userguide
Pathway Browser
How do I search ?
Details Panel
Analysis Tools
Analysis Data
Analysis Gene Expression
Species Comparison
Tissue Distribution
Diseases
Cytomics
Review Status of Reactome Events
ReactomeFIViz
Developer's Zone
Graph Database
Analysis Service
Content Service
Pathways Overview
Pathway Diagrams
Icon Info
EHLD Specs & Guidelines
Icon Library Guidelines
Data Model
Curator Guide
Release Documentation
Computationally inferred events
FAQ
Linking to Us
Citing us
Tools
Pathway Browser
Analyse gene list
Analyse gene expression
Species Comparison
Tissue Distribution
Analysis Service
Content Service
ReactomeFIViz
Advanced Data Search
Site Search
Community
Contribute Pathway Knowledge
Icon Library
Outreach
Events
Publications
Partners
Contributors
Resources Guide
Download
About
What is Reactome ?
News
Team
Scientific Advisory Board
Funding
Editorial Calendar
Release Calendar
Statistics
Our Logo
License Agreement
Privacy Notice
Disclaimer
Digital Preservation
Contact us
Content
Table of Contents
DOIs
Data Schema
Reactome Research Spotlight
ORCID Integration Project
COVID-19 Disease Pathways
Docs
Userguide
Pathway Browser
How do I search ?
Details Panel
Analysis Tools
Analysis Data
Analysis Gene Expression
Species Comparison
Tissue Distribution
Diseases
Cytomics
Review Status of Reactome Events
ReactomeFIViz
Developer's Zone
Graph Database
Analysis Service
Content Service
Pathways Overview
Pathway Diagrams
Icon Info
EHLD Specs & Guidelines
Icon Library Guidelines
Data Model
Curator Guide
Release Documentation
Computationally inferred events
FAQ
Linking to Us
Citing us
Tools
Pathway Browser
Analyse gene list
Analyse gene expression
Species Comparison
Tissue Distribution
Analysis Service
Content Service
ReactomeFIViz
Advanced Data Search
Site Search
Community
Contribute Pathway Knowledge
Icon Library
Outreach
Events
Publications
Partners
Contributors
Resources Guide
Download
Search ...
Go!
CSF2RB [plasma membrane]
Stable Identifier
R-HSA-879960
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
plasma membrane
Synonyms
IL3RB, Cytokine receptor common subunit beta, GM-CSF/IL-3/IL-5 receptor common beta chain, CD131
Icon
Locations in the PathwayBrowser
Expand all
Disease (Homo sapiens)
Diseases of metabolism (Homo sapiens)
Diseases associated with surfactant metabolism (Homo sapiens)
Defective CSF2RA causes SMDP4 (Homo sapiens)
Defective CSF2RA does not bind SFTPs (Homo sapiens)
CSF2RA G174R:CSF2RB [plasma membrane] (Homo sapiens)
CSF2RB [plasma membrane] (Homo sapiens)
Immune System (Homo sapiens)
Cytokine Signaling in Immune system (Homo sapiens)
Signaling by Interleukins (Homo sapiens)
Interleukin-3, Interleukin-5 and GM-CSF signaling (Homo sapiens)
Activation of STAT5a/b by JAK2 (Homo sapiens)
High affinity binding complex dimers of cytokine receptors using Bc, activated JAK2:p-STAT5 [plasma membrane] (Homo sapiens)
High affinity GM-CSF receptor complex dimer, activated JAK2:p-STAT5 [plasma membrane] (Homo sapiens)
High affinity GM-CSF receptor complex dimer, activated JAK2 [plasma membrane] (Homo sapiens)
GM-CSF:GM-CSF receptor alpha subunit:Common beta chain:p-JAK2 [plasma membrane] (Homo sapiens)
IL3RB:p-Y1007-JAK2 [plasma membrane] (Homo sapiens)
CSF2RB [plasma membrane] (Homo sapiens)
High affinity IL-5 receptor complex dimer, activated JAK2:p-STAT5 [plasma membrane] (Homo sapiens)
High affinity IL-5 receptor complex dimer, p-JAK2 [plasma membrane] (Homo sapiens)
IL5 homodimer:IL5RA:Common beta chain:p-JAK2 [plasma membrane] (Homo sapiens)
IL3RB:p-Y1007-JAK2 [plasma membrane] (Homo sapiens)
CSF2RB [plasma membrane] (Homo sapiens)
IL3:IL3R active complex, activated JAK2:p-STAT5 [plasma membrane] (Homo sapiens)
IL3:IL3R active complex, p-Y1007-JAK2 [plasma membrane] (Homo sapiens)
IL3:IL3RA:IL3RB:p-Y1007-JAK2 [plasma membrane] (Homo sapiens)
IL3RB:p-Y1007-JAK2 [plasma membrane] (Homo sapiens)
CSF2RB [plasma membrane] (Homo sapiens)
High affinity binding complex dimers of cytokine receptors using Bc. activated JAK2:STAT5 [plasma membrane] (Homo sapiens)
High affinity GM-CSF receptor complex dimer, activated JAK2:STAT5 [plasma membrane] (Homo sapiens)
High affinity GM-CSF receptor complex dimer, activated JAK2 [plasma membrane] (Homo sapiens)
GM-CSF:GM-CSF receptor alpha subunit:Common beta chain:p-JAK2 [plasma membrane] (Homo sapiens)
IL3RB:p-Y1007-JAK2 [plasma membrane] (Homo sapiens)
CSF2RB [plasma membrane] (Homo sapiens)
High affinity IL-5 receptor complex dimer, activated JAK2:STAT5 [plasma membrane] (Homo sapiens)
High affinity IL-5 receptor complex dimer, p-JAK2 [plasma membrane] (Homo sapiens)
IL5 homodimer:IL5RA:Common beta chain:p-JAK2 [plasma membrane] (Homo sapiens)
IL3RB:p-Y1007-JAK2 [plasma membrane] (Homo sapiens)
CSF2RB [plasma membrane] (Homo sapiens)
IL3:IL3R active complex, activated JAK2:STAT5 [plasma membrane] (Homo sapiens)
IL3:IL3R active complex, p-Y1007-JAK2 [plasma membrane] (Homo sapiens)
IL3:IL3RA:IL3RB:p-Y1007-JAK2 [plasma membrane] (Homo sapiens)
IL3RB:p-Y1007-JAK2 [plasma membrane] (Homo sapiens)
CSF2RB [plasma membrane] (Homo sapiens)
GM-CSF receptor alpha:GM-CSF binds Bc (Homo sapiens)
GM-CSF:GM-CSF receptor alpha subunit:Common beta chain:JAK2 [plasma membrane] (Homo sapiens)
IL3RB:JAK2 [plasma membrane] (Homo sapiens)
CSF2RB [plasma membrane] (Homo sapiens)
IL3RB:JAK2 [plasma membrane] (Homo sapiens)
CSF2RB [plasma membrane] (Homo sapiens)
IL3RB is phosphorylated on Ser-585 (Homo sapiens)
High affinity binding complex dimers of cytokine receptors using Bc, inactive JAK2 [plasma membrane] (Homo sapiens)
High affinity GM-CSF receptor complex dimer, inactive JAK2 [plasma membrane] (Homo sapiens)
GM-CSF:GM-CSF receptor alpha subunit:Common beta chain:JAK2 [plasma membrane] (Homo sapiens)
IL3RB:JAK2 [plasma membrane] (Homo sapiens)
CSF2RB [plasma membrane] (Homo sapiens)
High affinity IL-3 receptor complex dimer, inactive JAK2 [plasma membrane] (Homo sapiens)
IL3:IL3RA:IL3RB:JAK2 [plasma membrane] (Homo sapiens)
IL3RB:JAK2 [plasma membrane] (Homo sapiens)
CSF2RB [plasma membrane] (Homo sapiens)
High affinity IL-5 receptor complex dimer, inactive JAK2 [plasma membrane] (Homo sapiens)
IL5 homodimer:IL5RA:Common beta chain:JAK2 [plasma membrane] (Homo sapiens)
IL3RB:JAK2 [plasma membrane] (Homo sapiens)
CSF2RB [plasma membrane] (Homo sapiens)
Interleukin-3 receptor alpha: Interleukin-3 binds IL3RB:JAK2 (Homo sapiens)
IL3:IL3RA:IL3RB:JAK2 [plasma membrane] (Homo sapiens)
IL3RB:JAK2 [plasma membrane] (Homo sapiens)
CSF2RB [plasma membrane] (Homo sapiens)
IL3RB:JAK2 [plasma membrane] (Homo sapiens)
CSF2RB [plasma membrane] (Homo sapiens)
Interleukin-5:Interleukin-5 receptor alpha binds IL3RB:JAK2 (Homo sapiens)
IL3RB:JAK2 [plasma membrane] (Homo sapiens)
CSF2RB [plasma membrane] (Homo sapiens)
IL5 homodimer:IL5RA:Common beta chain:JAK2 [plasma membrane] (Homo sapiens)
IL3RB:JAK2 [plasma membrane] (Homo sapiens)
CSF2RB [plasma membrane] (Homo sapiens)
JAK2 is phosphorylated, activated (Homo sapiens)
High affinity binding complex dimers of cytokine receptors using Bc, activated JAK2 [plasma membrane] (Homo sapiens)
High affinity GM-CSF receptor complex dimer, activated JAK2 [plasma membrane] (Homo sapiens)
GM-CSF:GM-CSF receptor alpha subunit:Common beta chain:p-JAK2 [plasma membrane] (Homo sapiens)
IL3RB:p-Y1007-JAK2 [plasma membrane] (Homo sapiens)
CSF2RB [plasma membrane] (Homo sapiens)
High affinity IL-5 receptor complex dimer, p-JAK2 [plasma membrane] (Homo sapiens)
IL5 homodimer:IL5RA:Common beta chain:p-JAK2 [plasma membrane] (Homo sapiens)
IL3RB:p-Y1007-JAK2 [plasma membrane] (Homo sapiens)
CSF2RB [plasma membrane] (Homo sapiens)
IL3:IL3R active complex, p-Y1007-JAK2 [plasma membrane] (Homo sapiens)
IL3:IL3RA:IL3RB:p-Y1007-JAK2 [plasma membrane] (Homo sapiens)
IL3RB:p-Y1007-JAK2 [plasma membrane] (Homo sapiens)
CSF2RB [plasma membrane] (Homo sapiens)
High affinity binding complex dimers of cytokine receptors using Bc, inactive JAK2 [plasma membrane] (Homo sapiens)
High affinity GM-CSF receptor complex dimer, inactive JAK2 [plasma membrane] (Homo sapiens)
GM-CSF:GM-CSF receptor alpha subunit:Common beta chain:JAK2 [plasma membrane] (Homo sapiens)
IL3RB:JAK2 [plasma membrane] (Homo sapiens)
CSF2RB [plasma membrane] (Homo sapiens)
High affinity IL-3 receptor complex dimer, inactive JAK2 [plasma membrane] (Homo sapiens)
IL3:IL3RA:IL3RB:JAK2 [plasma membrane] (Homo sapiens)
IL3RB:JAK2 [plasma membrane] (Homo sapiens)
CSF2RB [plasma membrane] (Homo sapiens)
High affinity IL-5 receptor complex dimer, inactive JAK2 [plasma membrane] (Homo sapiens)
IL5 homodimer:IL5RA:Common beta chain:JAK2 [plasma membrane] (Homo sapiens)
IL3RB:JAK2 [plasma membrane] (Homo sapiens)
CSF2RB [plasma membrane] (Homo sapiens)
STAT5 is recruited by JAK2 (Homo sapiens)
High affinity binding complex dimers of cytokine receptors using Bc, activated JAK2 [plasma membrane] (Homo sapiens)
High affinity GM-CSF receptor complex dimer, activated JAK2 [plasma membrane] (Homo sapiens)
GM-CSF:GM-CSF receptor alpha subunit:Common beta chain:p-JAK2 [plasma membrane] (Homo sapiens)
IL3RB:p-Y1007-JAK2 [plasma membrane] (Homo sapiens)
CSF2RB [plasma membrane] (Homo sapiens)
High affinity IL-5 receptor complex dimer, p-JAK2 [plasma membrane] (Homo sapiens)
IL5 homodimer:IL5RA:Common beta chain:p-JAK2 [plasma membrane] (Homo sapiens)
IL3RB:p-Y1007-JAK2 [plasma membrane] (Homo sapiens)
CSF2RB [plasma membrane] (Homo sapiens)
IL3:IL3R active complex, p-Y1007-JAK2 [plasma membrane] (Homo sapiens)
IL3:IL3RA:IL3RB:p-Y1007-JAK2 [plasma membrane] (Homo sapiens)
IL3RB:p-Y1007-JAK2 [plasma membrane] (Homo sapiens)
CSF2RB [plasma membrane] (Homo sapiens)
High affinity binding complex dimers of cytokine receptors using Bc. activated JAK2:STAT5 [plasma membrane] (Homo sapiens)
High affinity GM-CSF receptor complex dimer, activated JAK2:STAT5 [plasma membrane] (Homo sapiens)
High affinity GM-CSF receptor complex dimer, activated JAK2 [plasma membrane] (Homo sapiens)
GM-CSF:GM-CSF receptor alpha subunit:Common beta chain:p-JAK2 [plasma membrane] (Homo sapiens)
IL3RB:p-Y1007-JAK2 [plasma membrane] (Homo sapiens)
CSF2RB [plasma membrane] (Homo sapiens)
High affinity IL-5 receptor complex dimer, activated JAK2:STAT5 [plasma membrane] (Homo sapiens)
High affinity IL-5 receptor complex dimer, p-JAK2 [plasma membrane] (Homo sapiens)
IL5 homodimer:IL5RA:Common beta chain:p-JAK2 [plasma membrane] (Homo sapiens)
IL3RB:p-Y1007-JAK2 [plasma membrane] (Homo sapiens)
CSF2RB [plasma membrane] (Homo sapiens)
IL3:IL3R active complex, activated JAK2:STAT5 [plasma membrane] (Homo sapiens)
IL3:IL3R active complex, p-Y1007-JAK2 [plasma membrane] (Homo sapiens)
IL3:IL3RA:IL3RB:p-Y1007-JAK2 [plasma membrane] (Homo sapiens)
IL3RB:p-Y1007-JAK2 [plasma membrane] (Homo sapiens)
CSF2RB [plasma membrane] (Homo sapiens)
The common beta chain IL3RB binds JAK2 (Homo sapiens)
CSF2RB [plasma membrane] (Homo sapiens)
IL3RB:JAK2 [plasma membrane] (Homo sapiens)
CSF2RB [plasma membrane] (Homo sapiens)
The receptor is activated (Homo sapiens)
High affinity binding complex dimers of cytokine receptors using Bc, inactive JAK2 [plasma membrane] (Homo sapiens)
High affinity GM-CSF receptor complex dimer, inactive JAK2 [plasma membrane] (Homo sapiens)
GM-CSF:GM-CSF receptor alpha subunit:Common beta chain:JAK2 [plasma membrane] (Homo sapiens)
IL3RB:JAK2 [plasma membrane] (Homo sapiens)
CSF2RB [plasma membrane] (Homo sapiens)
High affinity IL-3 receptor complex dimer, inactive JAK2 [plasma membrane] (Homo sapiens)
IL3:IL3RA:IL3RB:JAK2 [plasma membrane] (Homo sapiens)
IL3RB:JAK2 [plasma membrane] (Homo sapiens)
CSF2RB [plasma membrane] (Homo sapiens)
High affinity IL-5 receptor complex dimer, inactive JAK2 [plasma membrane] (Homo sapiens)
IL5 homodimer:IL5RA:Common beta chain:JAK2 [plasma membrane] (Homo sapiens)
IL3RB:JAK2 [plasma membrane] (Homo sapiens)
CSF2RB [plasma membrane] (Homo sapiens)
High affinity binding complexes of interleukin receptors using the Common beta chain [plasma membrane] (Homo sapiens)
GM-CSF:GM-CSF receptor alpha subunit:Common beta chain:JAK2 [plasma membrane] (Homo sapiens)
IL3RB:JAK2 [plasma membrane] (Homo sapiens)
CSF2RB [plasma membrane] (Homo sapiens)
IL3:IL3RA:IL3RB:JAK2 [plasma membrane] (Homo sapiens)
IL3RB:JAK2 [plasma membrane] (Homo sapiens)
CSF2RB [plasma membrane] (Homo sapiens)
IL5 homodimer:IL5RA:Common beta chain:JAK2 [plasma membrane] (Homo sapiens)
IL3RB:JAK2 [plasma membrane] (Homo sapiens)
CSF2RB [plasma membrane] (Homo sapiens)
Tyrosine kinases phosphorylate the receptor (Homo sapiens)
High affinity binding complex dimers of cytokine receptors using Bc, inactive JAK2 [plasma membrane] (Homo sapiens)
High affinity GM-CSF receptor complex dimer, inactive JAK2 [plasma membrane] (Homo sapiens)
GM-CSF:GM-CSF receptor alpha subunit:Common beta chain:JAK2 [plasma membrane] (Homo sapiens)
IL3RB:JAK2 [plasma membrane] (Homo sapiens)
CSF2RB [plasma membrane] (Homo sapiens)
High affinity IL-3 receptor complex dimer, inactive JAK2 [plasma membrane] (Homo sapiens)
IL3:IL3RA:IL3RB:JAK2 [plasma membrane] (Homo sapiens)
IL3RB:JAK2 [plasma membrane] (Homo sapiens)
CSF2RB [plasma membrane] (Homo sapiens)
High affinity IL-5 receptor complex dimer, inactive JAK2 [plasma membrane] (Homo sapiens)
IL5 homodimer:IL5RA:Common beta chain:JAK2 [plasma membrane] (Homo sapiens)
IL3RB:JAK2 [plasma membrane] (Homo sapiens)
CSF2RB [plasma membrane] (Homo sapiens)
Tyrosine kinases that phosphorylate the Common beta chain [plasma membrane] (Homo sapiens)
GM-CSF:GM-CSF receptor alpha subunit:Common beta chain:JAK2 [plasma membrane] (Homo sapiens)
IL3RB:JAK2 [plasma membrane] (Homo sapiens)
CSF2RB [plasma membrane] (Homo sapiens)
GM-CSF:GM-CSF receptor alpha subunit:Common beta chain:p-JAK2 [plasma membrane] (Homo sapiens)
IL3RB:p-Y1007-JAK2 [plasma membrane] (Homo sapiens)
CSF2RB [plasma membrane] (Homo sapiens)
IL3:IL3R active complex, p-Y1007-JAK2 [plasma membrane] (Homo sapiens)
IL3:IL3RA:IL3RB:p-Y1007-JAK2 [plasma membrane] (Homo sapiens)
IL3RB:p-Y1007-JAK2 [plasma membrane] (Homo sapiens)
CSF2RB [plasma membrane] (Homo sapiens)
IL3:IL3RA:IL3RB:JAK2 [plasma membrane] (Homo sapiens)
IL3RB:JAK2 [plasma membrane] (Homo sapiens)
CSF2RB [plasma membrane] (Homo sapiens)
IL5 homodimer:IL5RA:Common beta chain:JAK2 [plasma membrane] (Homo sapiens)
IL3RB:JAK2 [plasma membrane] (Homo sapiens)
CSF2RB [plasma membrane] (Homo sapiens)
IL5 homodimer:IL5RA:Common beta chain:p-JAK2 [plasma membrane] (Homo sapiens)
IL3RB:p-Y1007-JAK2 [plasma membrane] (Homo sapiens)
CSF2RB [plasma membrane] (Homo sapiens)
p-STAT5 dissociates from the receptor complex (Homo sapiens)
High affinity binding complex dimers of cytokine receptors using Bc, activated JAK2 [plasma membrane] (Homo sapiens)
High affinity GM-CSF receptor complex dimer, activated JAK2 [plasma membrane] (Homo sapiens)
GM-CSF:GM-CSF receptor alpha subunit:Common beta chain:p-JAK2 [plasma membrane] (Homo sapiens)
IL3RB:p-Y1007-JAK2 [plasma membrane] (Homo sapiens)
CSF2RB [plasma membrane] (Homo sapiens)
High affinity IL-5 receptor complex dimer, p-JAK2 [plasma membrane] (Homo sapiens)
IL5 homodimer:IL5RA:Common beta chain:p-JAK2 [plasma membrane] (Homo sapiens)
IL3RB:p-Y1007-JAK2 [plasma membrane] (Homo sapiens)
CSF2RB [plasma membrane] (Homo sapiens)
IL3:IL3R active complex, p-Y1007-JAK2 [plasma membrane] (Homo sapiens)
IL3:IL3RA:IL3RB:p-Y1007-JAK2 [plasma membrane] (Homo sapiens)
IL3RB:p-Y1007-JAK2 [plasma membrane] (Homo sapiens)
CSF2RB [plasma membrane] (Homo sapiens)
High affinity binding complex dimers of cytokine receptors using Bc, activated JAK2:p-STAT5 [plasma membrane] (Homo sapiens)
High affinity GM-CSF receptor complex dimer, activated JAK2:p-STAT5 [plasma membrane] (Homo sapiens)
High affinity GM-CSF receptor complex dimer, activated JAK2 [plasma membrane] (Homo sapiens)
GM-CSF:GM-CSF receptor alpha subunit:Common beta chain:p-JAK2 [plasma membrane] (Homo sapiens)
IL3RB:p-Y1007-JAK2 [plasma membrane] (Homo sapiens)
CSF2RB [plasma membrane] (Homo sapiens)
High affinity IL-5 receptor complex dimer, activated JAK2:p-STAT5 [plasma membrane] (Homo sapiens)
High affinity IL-5 receptor complex dimer, p-JAK2 [plasma membrane] (Homo sapiens)
IL5 homodimer:IL5RA:Common beta chain:p-JAK2 [plasma membrane] (Homo sapiens)
IL3RB:p-Y1007-JAK2 [plasma membrane] (Homo sapiens)
CSF2RB [plasma membrane] (Homo sapiens)
IL3:IL3R active complex, activated JAK2:p-STAT5 [plasma membrane] (Homo sapiens)
IL3:IL3R active complex, p-Y1007-JAK2 [plasma membrane] (Homo sapiens)
IL3:IL3RA:IL3RB:p-Y1007-JAK2 [plasma membrane] (Homo sapiens)
IL3RB:p-Y1007-JAK2 [plasma membrane] (Homo sapiens)
CSF2RB [plasma membrane] (Homo sapiens)
Metabolism of proteins (Homo sapiens)
Surfactant metabolism (Homo sapiens)
CSF2RA:CSF2RB binds SFTPs (Homo sapiens)
CSF2RA:CSF2RB [plasma membrane] (Homo sapiens)
CSF2RB [plasma membrane] (Homo sapiens)
CSF2RA:CSF2RB:SFTPs [plasma membrane] (Homo sapiens)
CSF2RA:CSF2RB [plasma membrane] (Homo sapiens)
CSF2RB [plasma membrane] (Homo sapiens)
SFTPs translocate from extracellular region to clathrin-coated vesicle (Homo sapiens)
CSF2RA:CSF2RB [plasma membrane] (Homo sapiens)
CSF2RB [plasma membrane] (Homo sapiens)
CSF2RA:CSF2RB:SFTPs [plasma membrane] (Homo sapiens)
CSF2RA:CSF2RB [plasma membrane] (Homo sapiens)
CSF2RB [plasma membrane] (Homo sapiens)
External Reference Information
External Reference
UniProt:P32927 CSF2RB
Gene Names
CSF2RB, IL3RB, IL5RB
Chain
signal peptide:1-16, chain:17-897
Reference Genes
BioGPS Gene:1439 CSF2RB
COSMIC (genes):CSF2RB CSF2RB
CTD Gene:1439 CSF2RB
dbSNP Gene:1439 CSF2RB
ENSEMBL:ENSG00000100368 CSF2RB
ENSEMBL_homo_sapiens_GENE:ENSG00000100368.15 CSF2RB
HGNC:2436 CSF2RB
KEGG Gene (Homo sapiens):1439 CSF2RB
Monarch:1439 CSF2RB
NCBI Gene:1439 CSF2RB
OMIM:138981 CSF2RB
UCSC:P32927 CSF2RB
Reference Transcript
RefSeq:XM_005261340.3 CSF2RB
RefSeq:NM_000395.2 CSF2RB
Other Identifiers
1086_at
11722724_a_at
11722725_a_at
11758608_s_at
1439
16929677
205159_PM_at
205159_at
3429537
37493_at
37494_at
3944565
3944566
3944568
3944569
3944571
3944572
3944573
3944574
3944575
3944576
3944577
3944578
3944579
3944580
3944582
3944583
3944584
3944585
3944589
3944590
3944591
3944592
3944593
3944594
3944595
3944596
3944597
3944598
3944599
3944600
3944601
3944602
3944603
3944604
3944605
8072757
A_14_P106200
A_14_P135880
A_23_P120899
A_33_P3341442
GE57996
GE80082
GO:0002376
GO:0004896
GO:0004912
GO:0004914
GO:0005515
GO:0005886
GO:0007165
GO:0007259
GO:0007585
GO:0009897
GO:0015026
GO:0016020
GO:0016064
GO:0019221
GO:0023052
GO:0030526
GO:0032496
GO:0036016
GO:0038023
GO:0038043
GO:0038156
GO:0038157
GO:0060089
GO:0070665
HMNXSV003003586
HMNXSV003033609
Hs.285401.0.S2_3p_at
ILMN_1798475
M59941_at
PH_hs_0014775
TC22000271.hg
Participates
as a component of
CSF2RA G174R:CSF2RB [plasma membrane] (Homo sapiens)
CSF2RA:CSF2RB [plasma membrane] (Homo sapiens)
IL3RB:Jak2 [plasma membrane] (Homo sapiens)
IL3RB:p-Y1007-JAK2 [plasma membrane] (Homo sapiens)
IL3RB:JAK2 [plasma membrane] (Homo sapiens)
as an input of
Mouse JAK2 binds human common beta chain (Homo sapiens)
The common beta chain IL3RB binds JAK2 (Homo sapiens)
Other forms of this molecule
CSF2RB S271L [plasma membrane]
p-Y593,Y628-CSF2RB [plasma membrane]
p-S585-CSF2RB [plasma membrane]
p-Y593-CSF2RB [plasma membrane]
CSF2RB R211Efs*54 [plasma membrane]
Inferred To
Csf2rb [plasma membrane]
(Mus musculus)
Csf2rb [plasma membrane]
(Rattus norvegicus)
CSF2RB [plasma membrane]
(Bos taurus)
CSF2RB [plasma membrane]
(Canis familiaris)
CSF2RB [plasma membrane]
(Gallus gallus)
CSF2RB [plasma membrane]
(Sus scrofa)
Homologues of CSF2RB [plasma membrane]
(Gallus gallus)
Homologues of CSF2RB [plasma membrane]
(Mus musculus)
Csf2rb2 [plasma membrane]
(Mus musculus)
Cross References
RefSeq
NP_000386.1
,
XP_005261397.1
Guide to Pharmacology - Targets
2306
OpenTargets
ENSG00000100368
HPA
ENSG00000100368-CSF2RB
GeneCards
P32927
Ensembl
ENSP00000384053
,
ENSP00000385271
,
ENST00000406230
,
ENST00000403662
,
ENSG00000100368
PRO
P32927
Pharos - Targets
P32927
Orphanet
15812
HMDB Protein
HMDBP01696
PDB
2NA9
,
1EGJ
,
1GH7
,
2GYS
,
4NKQ
,
8TLD
,
5DWU
,
2NA8
,
1C8P
Interactors (10)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:Q01344 IL5RA
1
IL5RA [plasma membrane]
(R-HSA-450072)
0.589
3
UniProt:P08700 IL3
1
IL3 [extracellular region]
(R-HSA-450059)
0.589
2
UniProt:O60674 JAK2
8
p-Y1007,Y1008-JAK2 [cytosol]
(R-HSA-9005327)
p-JAK2 [cytosol]
(R-HSA-210621)
p-Y813-JAK2 [cytosol]
(R-HSA-997248)
JAK2 V617F [nucleoplasm]
(R-HSA-5211269)
JAK2 [endosome lumen]
(R-HSA-2002372)
p-12Y-JAK2 [cytosol]
(R-HSA-2586516)
p-Y1007-JAK2 [cytosol]
(R-HSA-873799)
JAK2 [cytosol]
(R-HSA-210620)
0.564
4
UniProt:P05556 ITGB1
2
ITGB1 [endosome membrane]
(R-HSA-9611157)
ITGB1 [plasma membrane]
(R-HSA-57596)
0.544
5
UniProt:Q06124 PTPN11
4
p-Y542-PTPN11 [cytosol]
(R-HSA-1369081)
PTPN11 [nucleoplasm]
(R-HSA-8937745)
PTPN11 [cytosol]
(R-HSA-162563)
p-Y542,Y580-PTPN11 [cytosol]
(R-HSA-162573)
0.527
2
UniProt:P29353 SHC1
5
p-Y427-SHC1 [cytosol]
(R-HSA-74684)
p-Y349,Y350-SHC1 [cytosol]
(R-HSA-180276)
p-Y349,Y350,Y427-SHC1 [cytosol]
(R-HSA-912321)
SHC1 [cytosol]
(R-HSA-74680)
p-Y-SHC1 [cytosol]
(R-HSA-162568)
0.527
4
UniProt:P04141 CSF2 gene
1
CSF2 [extracellular region]
(R-HSA-517562)
0.524
2
UniProt:P05113 IL5
1
IL5 [extracellular region]
(R-HSA-447159)
0.524
2
UniProt:P29350 PTPN6
5
PTPN6 [specific granule lumen]
(R-HSA-6799641)
PTPN6 [extracellular region]
(R-HSA-6806315)
PTPN6 [tertiary granule lumen]
(R-HSA-6800952)
PTPN6 [nucleoplasm]
(R-HSA-9008911)
PTPN6 [cytosol]
(R-HSA-197938)
0.471
2
UniProt:P27986 PIK3R1
16
p-Y-PIK3R1 [cytosol]
(R-HSA-9680647)
PIK3R1 G376R [plasma membrane]
(R-HSA-2399717)
PIK3R1 K379E [plasma membrane]
(R-HSA-8944148)
PIK3R1 Y463_L466del [plasma membrane]
(R-HSA-2399546)
PIK3R1 H450_E451del [plasma membrane]
(R-HSA-2399545)
PIK3R1 R574_T576del [plasma membrane]
(R-HSA-2399544)
PIK3R1 D560Y [plasma membrane]
(R-HSA-2399421)
PIK3R1 N564D [plasma membrane]
(R-HSA-2399427)
PIK3R1 K459del [plasma membrane]
(R-HSA-2399554)
PIK3R1 N564K [plasma membrane]
(R-HSA-2399431)
PIK3R1 D560H [plasma membrane]
(R-HSA-2399432)
PIK3R1 R574I [plasma membrane]
(R-HSA-2399536)
PIK3R1 R574T [plasma membrane]
(R-HSA-2399540)
K63polyUb-PIK3R1 [cytosol]
(R-HSA-3080572)
PIK3R1 [cytosol]
(R-HSA-74789)
PIK3R1 [plasma membrane]
(R-HSA-198365)
0.462
4
© 2024
Reactome
Cite Us!
Cite Us!
Cite Us!
Warning!
Unable to extract citation. Please try again later.
Download As:
BibTeX
RIS
Text