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CYTH1 [Golgi membrane]
Stable Identifier
R-HSA-8847825
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
Golgi membrane
Synonyms
Cytohesin-1, PH, SEC7 and coiled-coil domain-containing protein 1, SEC7 homolog B2-1
Locations in the PathwayBrowser
Expand all
Vesicle-mediated transport (Homo sapiens)
Membrane Trafficking (Homo sapiens)
Intra-Golgi and retrograde Golgi-to-ER traffic (Homo sapiens)
Intra-Golgi traffic (Homo sapiens)
CYTH proteins bind ARF1:GTP (Homo sapiens)
ARF1:GTP:CYTH1,2,3,4 [Golgi membrane] (Homo sapiens)
CYTH1,2,3,4 [Golgi membrane] (Homo sapiens)
CYTH1 [Golgi membrane] (Homo sapiens)
CYTH proteins stimulate ARF1 GTPase activity (Homo sapiens)
ARF1:GDP:CYTH1,2,3,4 [Golgi membrane] (Homo sapiens)
CYTH1,2,3,4 [Golgi membrane] (Homo sapiens)
CYTH1 [Golgi membrane] (Homo sapiens)
ARF1:GTP:CYTH1,2,3,4 [Golgi membrane] (Homo sapiens)
CYTH1,2,3,4 [Golgi membrane] (Homo sapiens)
CYTH1 [Golgi membrane] (Homo sapiens)
External Reference Information
External Reference
UniProt:Q15438 CYTH1
Gene Names
CYTH1, D17S811E, PSCD1
Chain
chain:1-398
Reference Genes
BioGPS Gene:9267 CYTH1
COSMIC (genes):CYTH1 CYTH1
CTD Gene:9267 CYTH1
dbSNP Gene:9267 CYTH1
ENSEMBL:ENSG00000108669 CYTH1
ENSEMBL_homo_sapiens_GENE:ENSG00000108669.18 CYTH1
HGNC:9501 CYTH1
KEGG Gene (Homo sapiens):9267 CYTH1
Monarch:9267 CYTH1
NCBI Gene:9267 CYTH1
OMIM:182115 CYTH1
UCSC:Q15438 CYTH1
Reference Transcript
RefSeq:NM_001292019.1 CYTH1
RefSeq:NM_001292018.1 CYTH1
RefSeq:XM_011525477.1 CYTH1
RefSeq:NM_017456.3 CYTH1
RefSeq:NM_004762.3 CYTH1
Other Identifiers
11744293_a_at
11749337_a_at
11754351_a_at
16849501
202879_PM_s_at
202879_s_at
202880_PM_s_at
202880_s_at
3772526
3772527
3772528
3772540
3772541
3772542
3772543
3772547
3772549
3772552
3772554
3772555
3772556
3772557
3772558
3772560
3772561
3772564
3772580
38666_at
8018922
9267
A_23_P83781
A_33_P3332744
GE80345
GO:0000139
GO:0005085
GO:0005515
GO:0005737
GO:0005794
GO:0005829
GO:0005886
GO:0005912
GO:0005923
GO:0007155
GO:0007163
GO:0008289
GO:0009898
GO:0016020
GO:0016192
GO:0023052
GO:0030155
GO:0032012
GO:0043226
GO:0070161
GO:0090162
GO:0098772
HMNXSV003000455
Hs.1050.0.S1_3p_a_at
ILMN_1694084
ILMN_2403852
M85169_at
PH_hs_0000137
TC17001920.hg
g4758963_3p_a_at
Participates
as a member of
CYTH1,2,3,4 [Golgi membrane] (Homo sapiens)
Other forms of this molecule
CYTH1 [cytosol]
Inferred To
SEC7 [Golgi membrane]
(Saccharomyces cerevisiae)
step [Golgi membrane]
(Drosophila melanogaster)
sec71 [Golgi membrane]
(Schizosaccharomyces pombe)
sec72 [Golgi membrane]
(Schizosaccharomyces pombe)
cyth2 [Golgi membrane]
(Xenopus tropicalis)
CYTH1 [Golgi membrane]
(Bos taurus)
CYTH1 [Golgi membrane]
(Canis familiaris)
CYTH1 [Golgi membrane]
(Dictyostelium discoideum)
CYTH1 [Golgi membrane]
(Gallus gallus)
CYTH1 [Golgi membrane]
(Mus musculus)
CYTH1 [Golgi membrane]
(Rattus norvegicus)
CYTH1 [Golgi membrane]
(Sus scrofa)
Homologues of CYTH1 [Golgi membrane]
(Dictyostelium discoideum)
Homologues of CYTH1 [Golgi membrane]
(Schizosaccharomyces pombe)
Cross References
RefSeq
NP_004753.1
,
NP_001278948.1
,
NP_001278947.1
,
NP_059430.2
,
XP_011523779.1
OpenTargets
ENSG00000108669
GeneCards
Q15438
HPA
ENSG00000108669-CYTH1
Ensembl
ENSP00000465940
,
ENST00000446868
,
ENST00000591455
,
ENSG00000108669
,
ENSP00000465665
,
ENSP00000466512
,
ENST00000585509
,
ENST00000589297
,
ENSP00000389095
PRO
Q15438
Pharos - Targets
Q15438
PDB
4A4P
,
1BC9
HMDB Protein
HMDBP08338
Interactors (3)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:Q9UNE7 STUB1
1
STUB1 [cytosol]
(R-HSA-975970)
0.556
3
UniProt:P31749 AKT1
14
p-T308,S473-AKT1 E17K [nucleoplasm]
(R-HSA-2399994)
p-T308,S473-AKT1 E17K [cytosol]
(R-HSA-2243935)
AKT1 E17K [cytosol]
(R-HSA-2219526)
p-S473-AKT1 E17K [plasma membrane]
(R-HSA-2243944)
AKT1 E17K [plasma membrane]
(R-HSA-1500573)
p-S473-AKT1 [cytosol]
(R-HSA-9841264)
p-T308,S473-AKT1 [plasma membrane]
(R-HSA-199430)
p-Y315,Y326-AKT1 [cytosol]
(R-HSA-8848757)
p-T308-AKT1 [cytosol]
(R-HSA-198634)
AKT1 [cytosol]
(R-HSA-58252)
AKT1 [plasma membrane]
(R-HSA-199416)
p-S473-AKT1 [plasma membrane]
(R-HSA-377265)
p-T308,S473-AKT1 [cytosol]
(R-HSA-198356)
p-T308,S473-AKT1 [nucleoplasm]
(R-HSA-198357)
0.556
3
UniProt:P07900 HSP90AA1
8
HSP90AA1 [secretory granule lumen]
(R-HSA-6801515)
HSP90AA1 [ficolin-1-rich granule lumen]
(R-HSA-6801470)
HSP90AA1 [plasma membrane]
(R-HSA-534996)
HSP90AA1 [endocytic vesicle lumen]
(R-HSA-3221912)
HSP90AA1 [extracellular region]
(R-HSA-3221946)
HSP90AA1 [nucleoplasm]
(R-HSA-5082401)
HSP90AA1 [cytosol]
(R-HSA-192864)
HSP90AA1 [lysosomal lumen]
(R-HSA-9622850)
0.556
3
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