Reactome | CYTH1 [Golgi membrane]

CYTH1 [Golgi membrane]

Stable Identifier

R-HSA-8847825

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

Golgi membrane

Synonyms

Cytohesin-1, PH, SEC7 and coiled-coil domain-containing protein 1, SEC7 homolog B2-1

Locations in the PathwayBrowser

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External Reference Information

External Reference

UniProt:Q15438 CYTH1

Gene Names

CYTH1, D17S811E, PSCD1

Chain

chain:1-398

Reference Genes

BioGPS Gene:9267 CYTH1

COSMIC (genes):CYTH1 CYTH1

CTD Gene:9267 CYTH1

dbSNP Gene:9267 CYTH1

ENSEMBL:ENSG00000108669 CYTH1

ENSEMBL:ENSG00000108669.17 CYTH1

HGNC:9501 CYTH1

KEGG Gene (Homo sapiens):9267 CYTH1

Monarch:9267 CYTH1

NCBI Gene:9267 CYTH1

OMIM:182115 CYTH1

UCSC:Q15438 CYTH1

Reference Transcript

Other Identifiers

11744293_a_at

11749337_a_at

11754351_a_at

16849501

202879_PM_s_at

202879_s_at

202880_PM_s_at

202880_s_at

3772526

3772527

3772528

3772540

3772541

3772542

3772543

3772547

3772549

3772552

3772554

3772555

3772556

3772557

3772558

3772560

3772561

3772564

3772580

38666_at

8018922

9267

A_23_P83781

A_33_P3332744

GE80345

GO:0000139

GO:0005085

GO:0005515

GO:0005737

GO:0005794

GO:0005829

GO:0005886

GO:0005912

GO:0005923

GO:0007155

GO:0007163

GO:0008289

GO:0009898

GO:0016020

GO:0016192

GO:0023052

GO:0030155

GO:0032012

GO:0043226

GO:0070161

GO:0090162

GO:0098772

HMNXSV003000455

Hs.1050.0.S1_3p_a_at

ILMN_1694084

ILMN_2403852

M85169_at

PH_hs_0000137

TC17001920.hg

g4758963_3p_a_at

Participates

as a member of

CYTH1,2,3,4 [Golgi membrane] (Homo sapiens)

Other forms of this molecule

CYTH1 [cytosol]

Inferred To

YEL1 [Golgi membrane] (Saccharomyces cerevisiae)

grp-1 [Golgi membrane] (Caenorhabditis elegans)

SYT1 [Golgi membrane] (Saccharomyces cerevisiae)

step [Golgi membrane] (Drosophila melanogaster)

cyth2 [Golgi membrane] (Xenopus tropicalis)

CYTH1 [Golgi membrane] (Bos taurus)

CYTH1 [Golgi membrane] (Canis familiaris)

CYTH1 [Golgi membrane] (Gallus gallus)

CYTH1 [Golgi membrane] (Mus musculus)

CYTH1 [Golgi membrane] (Plasmodium falciparum)

CYTH1 [Golgi membrane] (Rattus norvegicus)

CYTH1 [Golgi membrane] (Schizosaccharomyces pombe)

CYTH1 [Golgi membrane] (Sus scrofa)

sec73 [Golgi membrane] (Schizosaccharomyces pombe)

cyth1 [Golgi membrane] (Danio rerio)

Homologues of CYTH1 [Golgi membrane] (Saccharomyces cerevisiae)

Homologues of CYTH1 [Golgi membrane] (Schizosaccharomyces pombe)

Cross References

RefSeq

XP_011523779.1, NP_001278948.1, NP_059430.2, NP_004753.1, NP_001278947.1

OpenTargets

ENSG00000108669

GeneCards

Q15438

HPA

ENSG00000108669-CYTH1

Ensembl

ENSG00000108669, ENSP00000466512, ENSP00000465665, ENSP00000465940, ENST00000591455, ENST00000589297, ENSP00000389095, ENST00000585509, ENST00000446868

PRO

Q15438

Pharos - Targets

Q15438

HMDB Protein

HMDBP08338

PDB

1BC9, 4A4P

Interactors (3)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:Q9UNE7 STUB1	1	STUB1 [cytosol] (R-HSA-975970)	0.556	3
UniProt:P31749 AKT1	13	p-T308,S473-AKT1 E17K [nucleoplasm] (R-HSA-2399994) p-T308,S473-AKT1 E17K [cytosol] (R-HSA-2243935) AKT1 E17K [cytosol] (R-HSA-2219526) p-S473-AKT1 E17K [plasma membrane] (R-HSA-2243944) AKT1 E17K [plasma membrane] (R-HSA-1500573) p-Y315,Y326-AKT1 [cytosol] (R-HSA-8848757) p-T308,S473-AKT1 [plasma membrane] (R-HSA-199430) p-T308-AKT1 [cytosol] (R-HSA-198634) AKT1 [cytosol] (R-HSA-58252) AKT1 [plasma membrane] (R-HSA-199416) p-S473-AKT1 [plasma membrane] (R-HSA-377265) p-T308,S473-AKT1 [cytosol] (R-HSA-198356) p-T308,S473-AKT1 [nucleoplasm] (R-HSA-198357)	0.556	3
UniProt:P07900 HSP90AA1	8	HSP90AA1 [endocytic vesicle lumen] (R-HSA-3221912) HSP90AA1 [secretory granule lumen] (R-HSA-6801515) HSP90AA1 [extracellular region] (R-HSA-3221946) HSP90AA1 [ficolin-1-rich granule lumen] (R-HSA-6801470) HSP90AA1 [plasma membrane] (R-HSA-534996) HSP90AA1 [nucleoplasm] (R-HSA-5082401) HSP90AA1 [cytosol] (R-HSA-192864) HSP90AA1 [lysosomal lumen] (R-HSA-9622850)	0.556	3

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