Reactome | FAM3C [platelet dense granule lumen]

FAM3C [platelet dense granule lumen]

Stable Identifier

R-HSA-8848884

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

platelet dense granule lumen

Synonyms

Protein FAM3C, FAM3C_HUMAN

Locations in the PathwayBrowser

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External Reference Information

External Reference

UniProt:Q92520 FAM3C

Gene Names

FAM3C, ILEI, GS3786

Chain

signal peptide:1-24, chain:25-227

Reference Genes

BioGPS Gene:10447 FAM3C

COSMIC (genes):FAM3C FAM3C

CTD Gene:10447 FAM3C

dbSNP Gene:10447 FAM3C

ENSEMBL:ENSG00000196937 FAM3C

HGNC:18664 FAM3C

Monarch:10447 FAM3C

NCBI Gene:10447 FAM3C

OMIM:608618 FAM3C

UCSC:Q92520 FAM3C

Reference Transcript

Other Identifiers

10447

11742232_s_at

11743608_s_at

11743609_a_at

11748094_a_at

201889_PM_at

201889_at

240062_PM_at

240062_at

3070048

3070049

3070050

3070051

3070052

3070053

3070054

3070055

3070062

3070066

3070067

3070068

3070069

3070070

3070071

3070072

3070075

3070080

3070081

34321_i_at

34322_r_at

3971625

3971626

3971627

3971628

3971629

3971630

3971631

3971632

3971633

52627_at

80949_at

8142540

8166442

A_21_P0013755

A_23_P157365

A_23_P157371

A_32_P101689

D87120_at

GE57390

GE63221

GO:0005125

GO:0005515

GO:0005576

GO:0005615

GO:0005794

GO:0007165

GO:0008150

GO:0030246

GO:0031089

GO:0031410

GO:0043226

GO:0048018

GO:0070062

GO:0098772

HMNXSV003052407

Hs.153027.0.A1_3p_at

ILMN_1777261

ILMN_2368773

PH_hs_0027460

PH_hs_0033330

TC07001808.hg

TC0X001623.hg

g7661713_3p_at

Participates

as a member of

Platelet dense granule content [platelet dense granule lumen] (Homo sapiens)

Other forms of this molecule

FAM3C [extracellular region]

Inferred To

Fam3c [platelet dense granule lumen] (Mus musculus)

Fam3c [platelet dense granule lumen] (Rattus norvegicus)

FAM3C [platelet dense granule lumen] (Bos taurus)

FAM3C [platelet dense granule lumen] (Canis familiaris)

FAM3C [platelet dense granule lumen] (Gallus gallus)

FAM3C [platelet dense granule lumen] (Sus scrofa)

fam3c [platelet dense granule lumen] (Danio rerio)

fam3c [platelet dense granule lumen] (Xenopus tropicalis)

famp-1 [platelet dense granule lumen] (Caenorhabditis elegans)

Cross References

ENSEMBL

ENSP00000353025, ENST00000359943

OpenTargets

ENSG00000196937

HPA

ENSG00000196937-FAM3C

PRO

Q92520

Pharos - Targets

Q92520

PDB

5LC2

Interactors (11)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:Q96BA8 CREB3L1	7	CREB3L1 [Golgi membrane] (R-HSA-8874155) CREB3L1(427-519) [Golgi membrane] (R-HSA-8874139) CREB3L1(1-426) [Golgi membrane] (R-HSA-8874153) CREB3L1 [endoplasmic reticulum membrane] (R-HSA-8874157) CREB3L1(1-375) [cytosol] (R-HSA-8874215) CREB3L1(376-426) [Golgi membrane] (R-HSA-8874213) CREB3L1(1-375) [nucleoplasm] (R-HSA-8874222)	0.666	4
UniProt:P78310 CXADR	1	CXADR [plasma membrane] (R-HSA-197912)	0.556	3
UniProt:P16871 IL7R	3	IL7R [clathrin-coated endocytic vesicle membrane] (R-HSA-9028500) IL7R [plasma membrane] (R-HSA-449945) p-Y449-IL7R [plasma membrane] (R-HSA-1295531)	0.556	3
UniProt:Q15223 NECTIN1	1	PVRL1 [plasma membrane] (R-HSA-3008842)	0.556	3
UniProt:Q3KNW5 SLC10A6	1	SLC10A6 [plasma membrane] (R-HSA-433091)	0.556	3
UniProt:O15552 FFAR2	1	FFAR2 [plasma membrane] (R-HSA-443944)	0.556	3
UniProt:Q16623 STX1A	5	STX1A [plasma membrane] (R-HSA-449128) STX1A(?-288) [plasma membrane] (R-HSA-5246518) STX1A(1-?) [cytosol] (R-HSA-3065964) STX1A [cytosol] (R-HSA-9609866) STX1A [endoplasmic reticulum membrane] (R-HSA-9609878)	0.556	3
UniProt:Q12982 BNIP2	1	BNIP2 [cytosol] (R-HSA-200792)	0.556	3
UniProt:Q15116 PDCD1	2	PDCD1 [plasma membrane] (R-HSA-197604) p-Y223,Y248-PDCD1 [plasma membrane] (R-HSA-389736)	0.527	2
UniProt:Q9H2A9 CHST8	1	CHST8 [Golgi membrane] (R-HSA-6786024)	0.527	2
UniProt:Q9UNA3 A4GNT	1	A4GNT [Golgi membrane] (R-HSA-5694499)	0.527	2

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