Reactome | SEPP1 [extracellular region]

SEPP1 [extracellular region]

Stable Identifier

R-HSA-8848887

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

extracellular region

Synonyms

Selenoprotein P, SEPP1_HUMAN

Locations in the PathwayBrowser

Expand all

External Reference Information

External Reference

UniProt:P49908 SELENOP

Gene Names

SELENOP, SELP, SEPP1

Chain

signal peptide:1-19, chain:20-381

Reference Genes

BioGPS Gene:6414 SELENOP

COSMIC (genes):SELENOP SELENOP

CTD Gene:6414 SELENOP

dbSNP Gene:6414 SELENOP

ENSEMBL:ENSG00000250722 SELENOP

ENSEMBL_homo_sapiens_GENE:ENSG00000250722.6 SELENOP

HGNC:10751 SELENOP

KEGG Gene (Homo sapiens):6414 SELENOP

Monarch:6414 SELENOP

NCBI Gene:6414 SELENOP

OMIM:601484 SELENOP

UCSC:P49908 SELENOP

Reference Transcript

Other Identifiers

11731433_a_at

11741874_x_at

201427_PM_s_at

201427_s_at

2855286

2855287

2855288

2855289

2855290

2855291

2855292

2855293

2855295

2855296

2855299

2855300

2855303

2855304

2855305

2855306

2855308

2855309

2855313

34363_at

6414

8111915

A_33_P3358745

GE81505

GO:0001887

GO:0005576

GO:0005615

GO:0006979

GO:0007420

GO:0007626

GO:0008430

GO:0009791

GO:0019953

GO:0031089

GO:0031410

GO:0040008

GO:0043226

GO:0048856

GO:0070062

HMNXSV003027241

ILMN_1785071

ILMN_2204826

PH_hs_0028072

Z11793_at

g4885590_3p_a_at

Participates

as a member of

Platelet dense granule content [extracellular region] (Homo sapiens)

Other forms of this molecule

SEPP1 [platelet dense granule lumen]

Inferred To

Selenop [extracellular region] (Mus musculus)

Selenop [extracellular region] (Rattus norvegicus)

sepp1a [extracellular region] (Danio rerio)

SELENOP [extracellular region] (Bos taurus)

SELENOP [extracellular region] (Canis familiaris)

SEPP1 [extracellular region] (Gallus gallus)

Cross References

RefSeq

NP_005401.3, NP_001078955.1, NP_001087195.1

OpenTargets

ENSG00000250722

GeneCards

P49908

HPA

ENSG00000250722-SELENOP

Ensembl

ENST00000511224, ENST00000514985, ENSP00000425915, ENST00000506577, ENSP00000427671, ENSP00000420939, ENSG00000250722

PRO

P49908

Pharos - Targets

P49908

HMDB Protein

HMDBP10716

Interactors (1)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:P00533 EGFR	20	p-6Y-EGFR [clathrin-coated endocytic vesicle membrane] (R-HSA-8869138) p-5Y-EGFRvIII [plasma membrane] (R-HSA-1248649) EGFRvIII [plasma membrane] (R-HSA-1214162) p-6Y-EGFR E746_A750del;T790M [plasma membrane] (R-HSA-1182985) p-6Y-EGFR L858R;T790M [plasma membrane] (R-HSA-1182984) p-6Y-EGFR A767_V769dup [plasma membrane] (R-HSA-1996343) p-6Y-EGFR N771_H773dup [plasma membrane] (R-HSA-1996342) p-6Y-EGFR K739_I744dup [plasma membrane] (R-HSA-1996346) p-6Y-EGFR D770_N771insNPG [plasma membrane] (R-HSA-1996335) p-6Y-EGFR E746_A750del [plasma membrane] (R-HSA-1181214) p-6Y-EGFR L858R [plasma membrane] (R-HSA-1173211) p-6Y-EGFR G719S [plasma membrane] (R-HSA-1169417) p-6Y-EGFR L747_P753delinsS [plasma membrane] (R-HSA-1228038) p-6Y-EGFR L747_A750delinsP [plasma membrane] (R-HSA-1228044) p-6Y-EGFR L747_T751del [plasma membrane] (R-HSA-1228041) p-6Y-EGFR L747_S752del [plasma membrane] (R-HSA-1228040) p-6Y-EGFR L747_T751delinsP [plasma membrane] (R-HSA-1228042) p-6Y-EGFR E746_T751delinsA [plasma membrane] (R-HSA-1228037) p-6Y-EGFR E746_S752delinsV [plasma membrane] (R-HSA-1228039) p-6Y-EGFR L861Q [plasma membrane] (R-HSA-1177541)	0.553	2

Cite Us!