Reactome | SEPP1 [platelet dense granule lumen]

SEPP1 [platelet dense granule lumen]

Stable Identifier

R-HSA-8848897

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

platelet dense granule lumen

Synonyms

Selenoprotein P, SEPP1_HUMAN

Locations in the PathwayBrowser

Expand all

External Reference Information

External Reference

UniProt:P49908 SELENOP

Gene Names

SELENOP, SELP, SEPP1

Chain

signal peptide:1-19, chain:20-381

Reference Genes

BioGPS Gene:6414 SELENOP

COSMIC (genes):SELENOP SELENOP

COSMIC (genes):SELP SELENOP

CTD Gene:6414 SELENOP

dbSNP Gene:6414 SELENOP

ENSEMBL:ENSG00000250722 SELENOP

HGNC:10751 SELENOP

KEGG:hsa:6414 SELENOP

Monarch:6414 SELENOP

NCBI Gene:6414 SELENOP

OMIM:601484 SELENOP

UCSC:P49908 SELENOP

Reference Transcript

Other Identifiers

11731433_a_at

11741874_x_at

16995848

201427_PM_s_at

201427_s_at

229620_PM_at

229620_at

2855286

2855287

2855288

2855289

2855290

2855291

2855292

2855293

2855295

2855296

2855297

2855298

2855299

2855300

2855301

2855302

2855303

2855304

2855305

2855306

2855307

2855308

2855309

2855313

2855316

34363_at

45411_r_at

6414

8111915

A_33_P3358745

GE81505

GO:0001887

GO:0005576

GO:0005615

GO:0006979

GO:0007420

GO:0007626

GO:0008430

GO:0009791

GO:0010269

GO:0016020

GO:0019953

GO:0022414

GO:0031089

GO:0040008

GO:0043226

GO:0048856

GO:0070062

HMNXSV003027241

Hs.24172.0.A1_3p_at

ILMN_1785071

ILMN_2204826

PH_hs_0028072

TC05001310.hg

Z11793_at

g4885590_3p_a_at

Participates

as a member of

Platelet dense granule content [platelet dense granule lumen] (Homo sapiens)

Other forms of this molecule

SEPP1 [extracellular region]

Inferred To

Selenop [platelet dense granule lumen] (Mus musculus)

Selenop [platelet dense granule lumen] (Rattus norvegicus)

SELENOP [platelet dense granule lumen] (Bos taurus)

SELENOP [platelet dense granule lumen] (Canis familiaris)

sepp1a [platelet dense granule lumen] (Danio rerio)

SEPP1 [platelet dense granule lumen] (Gallus gallus)

Cross References

ENSEMBL

ENST00000514985, ENST00000511224, ENST00000506577, ENSP00000427671, ENSP00000425915, ENSP00000420939, ENSG00000250722

OpenTargets

ENSG00000250722

GeneCards

SELENOP

HPA

ENSG00000250722-SELENOP

PRO

P49908

Pharos - Targets

P49908

HMDB Protein

HMDBP10716

Interactors (1)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:P00533 EGFR	20	p-6Y-EGFR [clathrin-coated endocytic vesicle membrane] (R-HSA-8869138) p-5Y-EGFRvIII [plasma membrane] (R-HSA-1248649) EGFRvIII [plasma membrane] (R-HSA-1214162) p-6Y-EGFR E746_A750del;T790M [plasma membrane] (R-HSA-1182985) p-6Y-EGFR L858R;T790M [plasma membrane] (R-HSA-1182984) p-6Y-EGFR A767_V769dup [plasma membrane] (R-HSA-1996343) p-6Y-EGFR N771_H773dup [plasma membrane] (R-HSA-1996342) p-6Y-EGFR K739_I744dup [plasma membrane] (R-HSA-1996346) p-6Y-EGFR D770_N771insNPG [plasma membrane] (R-HSA-1996335) p-6Y-EGFR E746_A750del [plasma membrane] (R-HSA-1181214) p-6Y-EGFR L858R [plasma membrane] (R-HSA-1173211) p-6Y-EGFR G719S [plasma membrane] (R-HSA-1169417) p-6Y-EGFR L747_P753delinsS [plasma membrane] (R-HSA-1228038) p-6Y-EGFR L747_A750delinsP [plasma membrane] (R-HSA-1228044) p-6Y-EGFR L747_T751del [plasma membrane] (R-HSA-1228041) p-6Y-EGFR L747_S752del [plasma membrane] (R-HSA-1228040) p-6Y-EGFR L747_T751delinsP [plasma membrane] (R-HSA-1228042) p-6Y-EGFR E746_T751delinsA [plasma membrane] (R-HSA-1228037) p-6Y-EGFR E746_S752delinsV [plasma membrane] (R-HSA-1228039) p-6Y-EGFR L861Q [plasma membrane] (R-HSA-1177541)	0.553	2

Cite Us!