Reactome | KHDRBS2 [nucleoplasm]

KHDRBS2 [nucleoplasm]

Stable Identifier

R-HSA-8849028

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

nucleoplasm

Synonyms

KH domain-containing, RNA-binding, signal transduction-associated protein 2, Sam68-like mammalian protein 1, SLM1, SLM-1

Locations in the PathwayBrowser for interactor UniProt:Q9P0T4 ZN581

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External Reference Information

External Reference

UniProt:Q5VWX1 KHDRBS2

Gene Names

KHDRBS2, SLM1

Chain

chain:1-349

Reference Genes

BioGPS Gene:202559 KHDRBS2

COSMIC (genes):KHDRBS2 KHDRBS2

CTD Gene:202559 KHDRBS2

dbSNP Gene:202559 KHDRBS2

ENSEMBL:ENSG00000112232 KHDRBS2

ENSEMBL:ENSG00000112232.10 KHDRBS2

HGNC:18114 KHDRBS2

KEGG Gene (Homo sapiens):202559 KHDRBS2

Monarch:202559 KHDRBS2

NCBI Gene:202559 KHDRBS2

OMIM:610487 KHDRBS2

UCSC:Q5VWX1 KHDRBS2

Reference Transcript

RefSeq:NM_152688.3 KHDRBS2

Other Identifiers

11735663_at

11747846_s_at

17020499

202559

215527_PM_at

215527_at

2959052

2959053

2959054

2959055

2959059

2959069

2959086

2959087

2959091

2959097

2959104

2959110

2959111

2959112

2959120

32024_at

8127370

A_23_P366453

GO:0000381

GO:0003676

GO:0003723

GO:0003729

GO:0005515

GO:0005634

GO:0005654

GO:0006397

GO:0008143

GO:0008266

GO:0016071

GO:0017124

GO:0042169

GO:0043226

GO:0048024

Hs.226014.0.S1_3p_at

PH_hs_0032115

TC06001842.hg

Participates

as an input of

PTK6 phosphorylates KHDRBS2 (Homo sapiens)

Other forms of this molecule

p-Y-KHDRBS2 [nucleoplasm]

Inferred To

khdrbs2 [nucleoplasm] (Danio rerio)

khdrbs2 [nucleoplasm] (Xenopus tropicalis)

Khdrbs2 [nucleoplasm] (Mus musculus)

Khdrbs2 [nucleoplasm] (Rattus norvegicus)

KHDRBS2 [nucleoplasm] (Bos taurus)

KHDRBS2 [nucleoplasm] (Canis familiaris)

KHDRBS2 [nucleoplasm] (Gallus gallus)

KHDRBS2 [nucleoplasm] (Sus scrofa)

qkr54B [nucleoplasm] (Drosophila melanogaster)

Cross References

RefSeq

NP_689901.2

OpenTargets

ENSG00000112232

HPA

ENSG00000112232-KHDRBS2

GeneCards

Q5VWX1

Ensembl

ENSG00000112232, ENSP00000281156, ENST00000281156

PRO

Q5VWX1

Pharos - Targets

Q5VWX1

Interactors (51)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:P38159 RBMX	2	RBMX [cytosol] (R-HSA-9715135) RBMX [nucleoplasm] (R-HSA-71939)	0.852	10
UniProt:P98179 RBM3			0.83	8
UniProt:Q8WWY3 PRPF31	1	PRPF31 [nucleoplasm] (R-HSA-6806772)	0.795	8
UniProt:P29597 TYK2	5	p-Y-TYK2 [cytosol] (R-HSA-6784366) p-TYK2 [cytosol] (R-HSA-8950424) TYK2 [cytosol] (R-HSA-877348) p-Y1054,Y1055-TYK2 [cytosol] (R-HSA-909682) p-Y1054-TYK2 [cytosol] (R-HSA-1112598)	0.781	7
UniProt:Q96MU7 YTDC1			0.718	6
UniProt:P79522 PRR3			0.718	6
UniProt:Q9NQX5 NPDC1	1	NPDC1 [plasma membrane] (R-HSA-8959647)	0.718	6
UniProt:O00560 SDCBP	3	SDCBP [extracellular region] (R-HSA-6806206) SDCBP [azurophil granule lumen] (R-HSA-6799372) SDCBP [cytosol] (R-HSA-373639)	0.718	6
UniProt:Q92608 DOCK2	3	DOCK2 [specific granule lumen] (R-HSA-6799558) DOCK2 [extracellular region] (R-HSA-6806310) DOCK2 [cytosol] (R-HSA-200938)	0.718	6
UniProt:Q8NEC5 CATSPER1	1	CATSPER1 [plasma membrane] (R-HSA-2534335)	0.718	6
UniProt:Q13882 PTK6	5	p-Y342-PTK6 [nucleoplasm] (R-HSA-8848937) p-Y342,Y447-PTK6 [cytosol] (R-HSA-8849103) p-Y351-PTK6 [cytosol] (R-HSA-8857570) p-Y342-PTK6 [cytosol] (R-HSA-8848007) PTK6 [cytosol] (R-HSA-8848000)	0.666	4
UniProt:O75525 KHDRBS3	2	KHDRSB3 [nucleoplasm] (R-HSA-8849040) p-Y-KHDRSB3 [nucleoplasm] (R-HSA-8849035)	0.666	4
UniProt:P61978-2 HNRNPK			0.666	4
UniProt:Q14011 CIRBP			0.666	4
UniProt:P02008 HBAZ			0.666	4
UniProt:Q6VB84 FX4L3			0.556	3
UniProt:Q03014 HHEX			0.556	3
UniProt:P18075 BMP7	1	BMP7(30-292) [extracellular region] (R-HSA-206223)	0.556	3
UniProt:Q9P0T4 ZN581			0.556	3
UniProt:Q13330 MTA1	2	MTA1 [nucleoplasm] (R-HSA-3465550) polySUMO2,3-K509-MTA1 [nucleoplasm] (R-HSA-3465537)	0.556	3
UniProt:Q6ZNH5 ZN497			0.556	3
UniProt:P98175 RBM10	1	RBM10 [nucleoplasm] (R-HSA-9770262)	0.556	3
IntAct:EBI-16428938 CCSB ISOFORM ID			0.556	3
UniProt:Q9Y3Y2 CHTOP	1	CHTOP [nucleoplasm] (R-HSA-8849147)	0.556	3
UniProt:Q9Y3Y2-3 CHTOP			0.556	3
UniProt:O43390 HNRNPR	1	HNRNPR [nucleoplasm] (R-HSA-71951)	0.556	3
UniProt:Q96EG3 ZN837			0.556	3
UniProt:Q96AH0 NABP1	1	NABP1 [nucleoplasm] (R-HSA-6814919)	0.556	3
UniProt:Q8WTP8 AEN			0.556	3
UniProt:A0A0S2Z5X4 A0A0S2Z5X4			0.556	3
IntAct:EBI-10188384 57727			0.556	3
UniProt:Q8NE01 CNNM3			0.556	3
UniProt:Q5D0E6-2 DALRD3			0.556	3
UniProt:Q8TBE0 BAHD1			0.556	3
UniProt:P38340 NTM1			0.556	3
UniProt:P40938 RFC3	1	RFC3 [nucleoplasm] (R-HSA-68431)	0.556	3
IntAct:EBI-10207182 255167			0.556	3
UniProt:P36084	2	MUD2 [nucleoplasm] (R-SCE-9630011) MUD2 [nucleoplasm] (R-SCE-71987)	0.556	3
UniProt:Q9UQ90 SPG7	1	SPG7 [mitochondrial inner membrane] (R-HSA-8953712)	0.556	3
UniProt:Q8TBB1 LNX1	1	LNX1 [cytosol] (R-HSA-8851641)	0.556	3
UniProt:Q8TAI1 TYMOS			0.556	3
UniProt:P0DMM9 SULT1A3	1	SULT1A3 [cytosol] (R-HSA-5634741)	0.556	3
UniProt:Q96PK6 RBM14	1	RBM14 [nucleoplasm] (R-HSA-8938345)	0.556	3
UniProt:P40507 AIR1			0.556	3
UniProt:Q8IXW0 LMTD2			0.556	3
UniProt:G3V1X1 G3V1X1			0.556	3
IntAct:EBI-22318346 CCSB ORF ID			0.556	3
UniProt:Q01844 EWS			0.553	2
UniProt:Q5VWX1 KHDRBS2	2	KHDRBS2 [nucleoplasm] (R-HSA-8849028) p-Y-KHDRBS2 [nucleoplasm] (R-HSA-8849031)	0.553	2
UniProt:Q92530 PSMF1	2	PSMF1 [nucleoplasm] (R-HSA-174308) PSMF1 [cytosol] (R-HSA-68818)	0.488	2
UniProt:O75791 GRAP2	1	GRAP2 [cytosol] (R-HSA-202367)	0.488	2

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