Reactome | KHDRSB3 [nucleoplasm]

KHDRSB3 [nucleoplasm]

Stable Identifier

R-HSA-8849040

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

nucleoplasm

Synonyms

KH domain-containing, RNA-binding, signal transduction-associated protein 3 GeneKHDRBS3, SLM2, Sam68-like mammalian protein 2, RNA-binding protein T-Star, Sam68-like phosphotyrosine protein, SALP

Locations in the PathwayBrowser for interactor UniProt:P38340 NTM1

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External Reference Information

External Reference

UniProt:O75525 KHDRBS3

Gene Names

KHDRBS3, SALP, SLM2

Chain

chain:1-346

Reference Genes

BioGPS Gene:10656 KHDRBS3

COSMIC (genes):KHDRBS3 KHDRBS3

CTD Gene:10656 KHDRBS3

dbSNP Gene:10656 KHDRBS3

ENSEMBL:ENSG00000131773 KHDRBS3

HGNC:18117 KHDRBS3

KEGG:hsa:10656 KHDRBS3

Monarch:10656 KHDRBS3

NCBI Gene:10656 KHDRBS3

OMIM:610421 KHDRBS3

UCSC:O75525 KHDRBS3

Reference Transcript

RefSeq:NM_006558.3 KHDRBS3

Other Identifiers

10656

11732318_a_at

11744581_a_at

17072979

209781_PM_s_at

209781_s_at

230249_PM_at

230249_at

3117383

3117385

3117386

3117387

3117388

3117389

3117390

3117399

3117400

3117402

3117403

3117404

3117405

3117406

3117412

3117416

3117420

3117431

3117432

3117433

3117434

3117435

3117436

3117437

3117438

3117441

31786_at

50742_at

8148448

A_14_P114504

A_14_P115968

A_14_P121384

A_23_P257335

A_33_P3332081

A_33_P3394727

GE54435

GO:0000381

GO:0003676

GO:0003723

GO:0003729

GO:0005515

GO:0005634

GO:0005654

GO:0006397

GO:0016071

GO:0017124

GO:0019904

GO:0032991

GO:0042802

GO:0048024

HMNXSV003024155

HMNXSV003045031

Hs.13565.1.A1_3p_at

ILMN_1691747

ILMN_1727790

PH_hs_0001310

PH_hs_0040513

TC08000778.hg

g3273831_3p_a_at

Participates

as an input of

PTK6 phosphorylates KHDRBS3 (Homo sapiens)

Other forms of this molecule

p-Y-KHDRSB3 [nucleoplasm]

Inferred To

KHDRSB3 [nucleoplasm] (Caenorhabditis elegans)

khdrbs3 [nucleoplasm] (Xenopus tropicalis)

Khdrbs3 [nucleoplasm] (Mus musculus)

Khdrbs3 [nucleoplasm] (Rattus norvegicus)

KHDRBS3 [nucleoplasm] (Bos taurus)

KHDRBS3 [nucleoplasm] (Canis familiaris)

KHDRBS3 [nucleoplasm] (Gallus gallus)

KHDRBS3 [nucleoplasm] (Sus scrofa)

qkr54B [nucleoplasm] (Drosophila melanogaster)

Cross References

RefSeq

NP_006549.1

OpenTargets

ENSG00000131773

ENSEMBL

ENSG00000131773, ENSP00000348108, ENST00000355849

GeneCards

KHDRBS3

HPA

ENSG00000131773-KHDRBS3

PRO

O75525

Pharos - Targets

O75525

GlyGen

O75525

PDB

5EMO, 5ELT, 5ELS, 5ELR, 5EL3

Interactors (43)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:Q5VWX1 KHDRBS2	2	KHDRBS2 [nucleoplasm] (R-HSA-8849028) p-Y-KHDRBS2 [nucleoplasm] (R-HSA-8849031)	0.801	7
UniProt:Q8WWY3 PRPF31	1	PRPF31 [nucleoplasm] (R-HSA-6806772)	0.718	6
UniProt:Q96MU7 YTHDC1	1	YTHDC1 [nucleoplasm] (R-HSA-9935812)	0.718	6
UniProt:Q07666 KHDRBS1	3	p-Y435,Y440,Y443-KHDRBS1 [nucleoplasm] (R-HSA-8848970) p-Y435,Y440,Y443-KHDRBS1 [cytosol] (R-HSA-8848995) KHDRBS1 [nucleoplasm] (R-HSA-8848941)	0.667	3
UniProt:P79522 PRR3			0.666	4
UniProt:Q9H9D4 ZN408			0.666	4
UniProt:Q8TBE0 BAHD1			0.666	4
UniProt:P38159 RBMX	2	RBMX [cytosol] (R-HSA-9715135) RBMX [nucleoplasm] (R-HSA-71939)	0.666	4
UniProt:P40938 RFC3	1	RFC3 [nucleoplasm] (R-HSA-68431)	0.556	3
UniProt:Q92835 INPP5D	2	INPP5D [cytosol] (R-HSA-197940) p-Y-INPP5D [cytosol] (R-HSA-9680730)	0.556	3
UniProt:Q92608 DOCK2	3	DOCK2 [specific granule lumen] (R-HSA-6799558) DOCK2 [extracellular region] (R-HSA-6806310) DOCK2 [cytosol] (R-HSA-200938)	0.556	3
UniProt:P02008 HBAZ			0.556	3
UniProt:Q5BKZ1 ZN326			0.556	3
UniProt:Q86YV0 RASAL3	1	RASAL3 [cytosol] (R-HSA-5658226)	0.556	3
UniProt:Q92835-2 INPP5D			0.556	3
UniProt:Q8IXW0 LMTD2			0.556	3
UniProt:P25786 PSMA1	2	PSMA1 [cytosol] (R-HSA-68724) PSMA1 [nucleoplasm] (R-HSA-174333)	0.556	3
UniProt:Q3SY00 T10IP			0.556	3
UniProt:Q9UNE2 RPH3L			0.556	3
UniProt:P29597 TYK2	5	p-Y1054-TYK2 [cytosol] (R-HSA-1112598) p-Y1054,Y1055-TYK2 [cytosol] (R-HSA-909682) TYK2 [cytosol] (R-HSA-877348) p-TYK2 [cytosol] (R-HSA-8950424) p-Y-TYK2 [cytosol] (R-HSA-6784366)	0.556	3
UniProt:Q6IPE9 Q6IPE9			0.556	3
UniProt:Q9NQL9 DMRT3			0.556	3
UniProt:Q86XF7 ZN575			0.556	3
UniProt:P61978-2 HNRNPK			0.556	3
UniProt:P98179 RBM3			0.556	3
UniProt:Q96RF0 SNX18	1	SNX18 [cytosol] (R-HSA-8868038)	0.556	3
UniProt:Q9UK33 ZN580			0.556	3
UniProt:P38340 NTM1			0.556	3
UniProt:P29972 AQP1	1	AQP1 [plasma membrane] (R-HSA-431700)	0.556	3
UniProt:Q8IVT4 Q8IVT4			0.556	3
UniProt:Q8NE01 CNNM3			0.556	3
UniProt:Q86VE0 MYPOP			0.556	3
UniProt:Q9Y5E9 PCDBE			0.556	3
IntAct:EBI-10188384 57727			0.556	3
UniProt:Q9Y272 RASD1			0.556	3
UniProt:A0A0S2Z5X4 A0A0S2Z5X4			0.556	3
UniProt:Q8N5R6 CCD33			0.553	2
UniProt:P61978 HNRNPK	2	HNRNPK [nucleoplasm] (R-HSA-71945) polySUMO2-K422-HNRNPK [nucleoplasm] (R-HSA-4570532)	0.553	2
UniProt:Q8TBB1 LNX1	1	LNX1 [cytosol] (R-HSA-8851641)	0.553	2
UniProt:O75525 KHDRBS3	2	KHDRSB3 [nucleoplasm] (R-HSA-8849040) p-Y-KHDRSB3 [nucleoplasm] (R-HSA-8849035)	0.553	2
UniProt:Q9Y580 RBM7	1	RBM7 [nucleoplasm] (R-HSA-8985564)	0.553	2
UniProt:Q8WX92 NELFB	3	NELFB [nucleoplasm] (R-HSA-112427) NELFB [cytosol] (R-HSA-9603526) NELFB [mitochondrial outer membrane] (R-HSA-9603553)	0.524	2
UniProt:Q9BYB0 SHANK3	1	SHANK3 [cytosol] (R-HSA-6794277)	0.508	3

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