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GPKOW [nucleoplasm]
Stable Identifier
R-HSA-8850839
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
nucleoplasm
Synonyms
G patch domain and KOW motifs-containing protein, GPKOW_HUMAN
Locations in the PathwayBrowser for interactor UniProt:Q99961 SH3GL1
Expand all
Metabolism of RNA (Homo sapiens)
Processing of Capped Intron-Containing Pre-mRNA (Homo sapiens)
mRNA Splicing (Homo sapiens)
mRNA Splicing - Major Pathway (Homo sapiens)
Formation of the Spliceosomal B* complex (Homo sapiens)
GPKOW [nucleoplasm] (Homo sapiens)
Formation of the Spliceosomal Bact complex (Homo sapiens)
GPKOW [nucleoplasm] (Homo sapiens)
External Reference Information
External Reference
UniProt:Q92917 GPKOW
Gene Names
GPKOW, GPATC5, GPATCH5, T54
Chain
initiator methionine:, chain:2-476
Reference Genes
BioGPS Gene:27238 GPKOW
COSMIC (genes):GPKOW GPKOW
CTD Gene:27238 GPKOW
dbSNP Gene:27238 GPKOW
ENSEMBL:ENSG00000068394 GPKOW
ENSEMBL_homo_sapiens_GENE:ENSG00000068394.11 GPKOW
ENSEMBL_homo_sapiens_GENE:ENSG00000292204.1 GPKOW
HGNC:30677 GPKOW
KEGG Gene (Homo sapiens):27238 GPKOW
Monarch:27238 GPKOW
NCBI Gene:27238 GPKOW
OMIM:301003 GPKOW
UCSC:Q92917 GPKOW
Reference Transcript
RefSeq:NM_015698.5 GPKOW
Other Identifiers
11718412_at
17110800
203776_PM_at
203776_at
27238
4007818
4007819
4007820
4007821
4007822
4007823
4007824
4007825
4007826
4007827
4007829
4007830
4007831
41102_at
8172548
A_23_P114155
GE59332
GO:0000398
GO:0003676
GO:0003723
GO:0005515
GO:0005634
GO:0005654
GO:0005681
GO:0006397
GO:0008380
GO:0016071
GO:0043226
HMNXSV003021479
ILMN_1684197
PH_hs_0026555
PH_hs_0034177
TC0X001027.hg
U66359_at
g7662668_3p_at
Participates
as an output of
Formation of the Spliceosomal B* complex (Homo sapiens)
as a component of
Spliceosomal Bact complex [nucleoplasm] (Homo sapiens)
Spliceosomal Intermediate C Complex [nucleoplasm] (Homo sapiens)
as an input of
Formation of the Spliceosomal Bact complex (Homo sapiens)
Inferred To
gkow-1 [nucleoplasm]
(Caenorhabditis elegans)
Dmel\CG10324 [nucleoplasm]
(Drosophila melanogaster)
Gpkow [nucleoplasm]
(Mus musculus)
Gpkow [nucleoplasm]
(Rattus norvegicus)
GPKOW [nucleoplasm]
(Bos taurus)
GPKOW [nucleoplasm]
(Dictyostelium discoideum)
GPKOW [nucleoplasm]
(Gallus gallus)
GPKOW [nucleoplasm]
(Sus scrofa)
gpkow [nucleoplasm]
(Danio rerio)
gpkow [nucleoplasm]
(Xenopus tropicalis)
Ghost homologue of GPKOW [nucleoplasm]
(Canis familiaris)
cwf28 [nucleoplasm]
(Schizosaccharomyces pombe)
Cross References
RefSeq
NP_056513.2
OpenTargets
ENSG00000068394
HPA
ENSG00000068394-GPKOW
GeneCards
Q92917
Ensembl
ENSG00000068394
,
ENST00000156109
,
ENSP00000156109
PRO
Q92917
Pharos - Targets
Q92917
Orphanet
27522
PDB
7QTT
,
8CH6
,
7DVQ
Interactors (53)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:Q9BRD0 BUD13
1
BUD13 [nucleoplasm]
(R-HSA-9769522)
0.913
13
UniProt:Q08379 GOLGA2
3
p-S37-GOLGA2 [Golgi membrane]
(R-HSA-2172179)
GOLGA2 [endoplasmic reticulum-Golgi intermediate compartment membrane]
(R-HSA-2167933)
GOLGA2 [Golgi membrane]
(R-HSA-6808764)
0.781
9
UniProt:Q12933 TRAF2
5
TRAF2 [nucleoplasm]
(R-HSA-8862199)
K63polyUb-TRAF2 [nucleoplasm]
(R-HSA-8862194)
K63polyUb-TRAF2 [cytosol]
(R-HSA-8862193)
PolyUb-TRAF2 [cytosol]
(R-HSA-6782848)
TRAF2 [cytosol]
(R-HSA-66370)
0.781
7
UniProt:Q15560 TCEA2
0.781
7
UniProt:O60231 DHX16
1
DHX16 [nucleoplasm]
(R-HSA-8850837)
0.772
6
UniProt:Q9HAT0 ROPN1
1
ROPN1 [cytosol]
(R-HSA-5667048)
0.718
6
UniProt:P36406 TRI23
0.666
4
UniProt:Q99961 SH3GL1
1
SH3GL1 [cytosol]
(R-HSA-8867732)
0.666
8
UniProt:Q9Y250 LZTS1
0.556
3
UniProt:P31321 PRKAR1B
2
PRKAR1B [cytosol]
(R-HSA-57838)
PRKAR1B [ciliary base]
(R-HSA-5610409)
0.556
3
UniProt:Q96IJ6 GMPPA
1
GMPPA [cytosol]
(R-HSA-532565)
0.556
3
UniProt:Q96D03 DDT4L
0.556
3
UniProt:Q9UJV3-2 MID2
0.556
3
UniProt:Q9H0C1 ZMY12
0.556
3
UniProt:Q4G0R1 Q4G0R1
0.556
3
UniProt:Q5JR59-3 MTUS2
0.556
3
UniProt:O60504 SORBS3
1
SORBS3 [cytosol]
(R-HSA-445805)
0.556
3
UniProt:Q6FGM0 Q6FGM0
0.556
3
UniProt:Q9P2M1 LR2BP
0.556
3
UniProt:Q6P9H4 CNKR3
0.556
3
UniProt:Q96ED9-2 HOOK2
0.556
3
UniProt:O43189 PHF1
1
PHF1 [nucleoplasm]
(R-HSA-5084105)
0.556
3
UniProt:P62487 POLR2G
1
POLR2G [nucleoplasm]
(R-HSA-63517)
0.556
3
UniProt:O75031 HSF2B
0.556
3
UniProt:A6NLX3 SPDE4
0.556
3
UniProt:Q8N1B4 VPS52
1
VPS52 [trans-Golgi network membrane]
(R-HSA-6811029)
0.556
3
UniProt:P46439 GSTM5
1
GSTM5 [cytosol]
(R-HSA-176057)
0.556
3
UniProt:Q9P291 ARMX1
0.556
3
UniProt:Q9Y6D9 MAD1L1
1
MAD1L1 [cytosol]
(R-HSA-141433)
0.556
3
UniProt:Q63ZY3 KANK2
0.556
3
UniProt:Q04864-2 REL
0.556
3
UniProt:Q8TBB1 LNX1
1
LNX1 [cytosol]
(R-HSA-8851641)
0.556
5
UniProt:Q6FHY5 Q6FHY5
0.556
3
UniProt:Q5JST6 EFHC2
0.556
3
UniProt:Q9NRD5 PICK1
2
PICK1 [plasma membrane]
(R-HSA-416989)
PICK1 [endocytic vesicle membrane]
(R-HSA-417017)
0.556
3
UniProt:Q9UGI0 ZRANB1
1
ZRANB1 [cytosol]
(R-HSA-6781939)
0.556
3
UniProt:P23193 TCEA1
1
TCEA1 [nucleoplasm]
(R-HSA-65748)
0.556
3
UniProt:Q9Y6K9 IKBKG
12
IKBKG D406V [cytosol]
(R-HSA-5262943)
IKBKG L153R [cytosol]
(R-HSA-5262879)
IKBKG E391* [cytosol]
(R-HSA-5262924)
IKBKG C417R [cytosol]
(R-HSA-5262858)
IKBKG R173G [cytosol]
(R-HSA-5262966)
IKBKG R175P [cytosol]
(R-HSA-5262916)
IKBKG *420Wext*447 [cytosol]
(R-HSA-5262978)
monoSUMO1-K277,K309-IKBKG [nucleoplasm]
(R-HSA-4755449)
IKBKG [nucleoplasm]
(R-HSA-4755413)
K63polyUb-IKBKG [cytosol]
(R-HSA-202530)
Ub-285-IKBKG [cytosol]
(R-HSA-741397)
IKBKG [cytosol]
(R-HSA-168108)
0.556
3
UniProt:P14373 TRIM27
2
TRIM27 [nucleoplasm]
(R-HSA-2997690)
TRIM27 [cytosol]
(R-HSA-8851002)
0.556
3
UniProt:Q14696 MESD
0.556
3
UniProt:Q2TAC2 CCD57
0.556
3
UniProt:P07910 HNRNPC
3
HNRNPC [cytosol]
(R-HSA-9715136)
SUMO1-K250-HNRNPC [nucleoplasm]
(R-HSA-4570543)
HNRNPC [nucleoplasm]
(R-HSA-71933)
0.536
3
UniProt:Q8N128 F177A
0.527
2
UniProt:P02675 FGB
5
FGB(31-491) [platelet alpha granule lumen]
(R-HSA-140921)
FGB(31-491) [extracellular region]
(R-HSA-140846)
FGB [plasma membrane]
(R-HSA-140917)
FGB(31-44) [extracellular region]
(R-HSA-140876)
FGB [extracellular region]
(R-HSA-140584)
0.527
2
UniProt:P62136 PPP1CA
1
PPP1CA [cytosol]
(R-HSA-163525)
0.519
2
UniProt:P22694-2 PRKACB
0.508
4
UniProt:O43172 PRPF4
1
PRPF4 [nucleoplasm]
(R-HSA-71890)
0.508
2
UniProt:P98175 RBM10
1
RBM10 [nucleoplasm]
(R-HSA-9770262)
0.508
2
UniProt:Q9NYB0 TERF2IP
1
TERF2IP [nucleoplasm]
(R-HSA-174873)
0.508
2
UniProt:P51817 PRKX
1
PRKX [nucleoplasm]
(R-HSA-3222308)
0.508
2
UniProt:Q6P2Q9 PRPF8
1
PRPF8 [nucleoplasm]
(R-HSA-83810)
0.508
2
UniProt:Q92620 DHX38
1
DHX38 [nucleoplasm]
(R-HSA-72060)
0.508
2
UniProt:Q8NC51 SERB1
0.483
2
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