Reactome | UBE3D [cytosol]

UBE3D [cytosol]

Stable Identifier

R-HSA-8851647

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

cytosol

Synonyms

E3 ubiquitin-protein ligase E3D ecNumber6.3.2.-/ecNumber, UBE3D_HUMAN

Locations in the PathwayBrowser

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External Reference Information

External Reference

UniProt:Q7Z6J8 UBE3D

Gene Names

UBE3D, C6orf157, H10BH, UBE2CBP

Chain

initiator methionine:, chain:2-389

Reference Genes

BioGPS Gene:90025 UBE3D

COSMIC (genes):UBE3D UBE3D

CTD Gene:90025 UBE3D

dbSNP Gene:90025 UBE3D

ENSEMBL:ENSG00000118420 UBE3D

HGNC:21381 UBE3D

KEGG:hsa:90025 UBE3D

Monarch:90025 UBE3D

NCBI Gene:90025 UBE3D

OMIM:612495 UBE3D

UCSC:Q7Z6J8 UBE3D

Reference Transcript

Other Identifiers

11754207_a_at

11755983_a_at

1569262_3p_x_at

1569262_PM_x_at

1569262_x_at

17021167

227790_PM_at

227790_at

233327_PM_at

233327_at

2962689

2962690

2962691

2962697

2962712

2962713

2962714

2962715

2962716

2962720

2962721

2962722

2962725

2962726

2962727

2962729

2962731

2962732

2962733

2962734

2962738

2962739

2962740

2962741

2962742

47581_at

8127824

90025

A_23_P365327

A_24_P626931

A_33_P3369781

A_33_P3369786

GE85455

GE85456

GO:0000151

GO:0000209

GO:0003824

GO:0005515

GO:0005634

GO:0005737

GO:0005829

GO:0006513

GO:0016567

GO:0016740

GO:0030163

GO:0030332

GO:0031624

GO:0043161

GO:0043226

GO:0044390

GO:0051865

GO:0061630

GO:0140096

HMNXSV003019179

HMNXSV003040141

HMNXSV003047083

HMNXSV003050877

Hs.300141.2.A1_3p_at

Hs.326583.0.S1_3p_at

Hs2.367802.1.A1_3p_at

Hs2.367802.1.A1_3p_x_at

ILMN_1719103

ILMN_2127624

PH_hs_0038800

TC06001910.hg

TC06003739.hg

Participates

as a candidate of

E3 ligases in proteasomal degradation [cytosol] (Homo sapiens)

Inferred To

ube3d [cytosol] (Xenopus tropicalis)

UBE3D [cytosol] (Bos taurus)

UBE3D [cytosol] (Caenorhabditis elegans)

UBE3D [cytosol] (Canis familiaris)

UBE3D [cytosol] (Dictyostelium discoideum)

UBE3D [cytosol] (Gallus gallus)

UBE3D [cytosol] (Saccharomyces cerevisiae)

UBE3D [cytosol] (Schizosaccharomyces pombe)

UBE3D [cytosol] (Sus scrofa)

Ube3d [cytosol] (Mus musculus)

Ube3d [cytosol] (Rattus norvegicus)

Cross References

ENSEMBL

ENSP00000358762, ENSG00000118420, ENST00000369747

OpenTargets

ENSG00000118420

GeneCards

UBE3D

HPA

ENSG00000118420-UBE3D

PRO

Q7Z6J8

Pharos - Targets

Q7Z6J8

GlyGen

Q7Z6J8

Interactors (6)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:P59665 DEFA1	9	DEFA1(1-94) [Golgi lumen] (R-HSA-1467215) DEFA1(20-94) [Golgi lumen] (R-HSA-1467282) DEFA1(66-94) [Golgi lumen] (R-HSA-975663) DEFA1(20-65) [Golgi lumen] (R-HSA-8864970) DEFA1(66-94) [extracellular region] (R-HSA-1461998) DEFA1(66-94) [azurophil granule lumen] (R-HSA-1470038) DEFA1(65-94) [extracellular region] (R-HSA-1462022) omega-N-(ADP-ribosyl)-L-arginine-DEFA1(65-94) [extracellular region] (R-HSA-1972397) DEFA1(65-94) [azurophil granule lumen] (R-HSA-1470053)	0.527	2
UniProt:P31948 STIP1	1	STIP1 [cytosol] (R-HSA-443857)	0.527	3
UniProt:Q6PGQ7 BORA	3	p-7S,2T-BORA [cytosol] (R-HSA-4086411) p-8S,3T-BORA [cytosol] (R-HSA-3000330) BORA [cytosol] (R-HSA-2562607)	0.527	3
UniProt:P35813 PPM1A	2	PPM1A [nucleoplasm] (R-HSA-205813) PPM1A [cytosol] (R-HSA-380928)	0.527	2
UniProt:Q9UMX1 SUFU	3	SUFU [ciliary base] (R-HSA-5610424) SUFU [cytosol] (R-HSA-445455) SUFU [ciliary tip] (R-HSA-5610426)	0.527	2
UniProt:O75344 FKBP6	2	FKBP6 [nucleoplasm] (R-HSA-912512) FKBP6 [cytosol] (R-HSA-5601923)	0.527	2

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