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TRAIP [cytosol]
Stable Identifier
R-HSA-8851652
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
cytosol
Synonyms
E3 ubiquitin-protein ligase TRAIP ecNumber6.3.2.-/ecNumber, TRAIP_HUMAN
Locations in the PathwayBrowser
Expand all
Immune System (Homo sapiens)
Adaptive Immune System (Homo sapiens)
Class I MHC mediated antigen processing & presentation (Homo sapiens)
Antigen processing: Ubiquitination & Proteasome degradation (Homo sapiens)
Interaction of E3 with substrate and E2-Ub complex (Homo sapiens)
Ag-substrate:E3:E2:Ub [cytosol] (Homo sapiens)
E3 ligases in proteasomal degradation [cytosol] (Homo sapiens)
TRAIP [cytosol] (Homo sapiens)
E3 ligases in proteasomal degradation [cytosol] (Homo sapiens)
TRAIP [cytosol] (Homo sapiens)
Polyubiquitination of substrate (Homo sapiens)
E3 ligases in proteasomal degradation [cytosol] (Homo sapiens)
TRAIP [cytosol] (Homo sapiens)
E3:K48-polyubiquitinated substrate [cytosol] (Homo sapiens)
E3 ligases in proteasomal degradation [cytosol] (Homo sapiens)
TRAIP [cytosol] (Homo sapiens)
E3:Ub:substrate [cytosol] (Homo sapiens)
E3 ligases in proteasomal degradation [cytosol] (Homo sapiens)
TRAIP [cytosol] (Homo sapiens)
Release of E3 from polyubiquitinated substrate (Homo sapiens)
E3 ligases in proteasomal degradation [cytosol] (Homo sapiens)
TRAIP [cytosol] (Homo sapiens)
E3:K48-polyubiquitinated substrate [cytosol] (Homo sapiens)
E3 ligases in proteasomal degradation [cytosol] (Homo sapiens)
TRAIP [cytosol] (Homo sapiens)
Transfer of Ub from E2 to substrate and release of E2 (Homo sapiens)
Ag-substrate:E3:E2:Ub [cytosol] (Homo sapiens)
E3 ligases in proteasomal degradation [cytosol] (Homo sapiens)
TRAIP [cytosol] (Homo sapiens)
E3 ligases in proteasomal degradation [cytosol] (Homo sapiens)
TRAIP [cytosol] (Homo sapiens)
E3:Ub:substrate [cytosol] (Homo sapiens)
E3 ligases in proteasomal degradation [cytosol] (Homo sapiens)
TRAIP [cytosol] (Homo sapiens)
External Reference Information
External Reference
UniProt:Q9BWF2 TRAIP
Gene Names
TRAIP, RNF206, TRIP
Chain
chain:1-469
Reference Genes
BioGPS Gene:10293 TRAIP
COSMIC (genes):TRAIP TRAIP
CTD Gene:10293 TRAIP
dbSNP Gene:10293 TRAIP
ENSEMBL:ENSG00000183763 TRAIP
HGNC:30764 TRAIP
KEGG:hsa:10293 TRAIP
Monarch:10293 TRAIP
NCBI Gene:10293 TRAIP
OMIM:605958 TRAIP
UCSC:Q9BWF2 TRAIP
Reference Transcript
RefSeq:NM_005879.2 TRAIP
Other Identifiers
10293
11755941_a_at
11762212_at
16954251
205598_PM_at
205598_at
2674809
2674810
2674811
2674812
2674813
2674814
2674815
2674816
2674818
2674820
2674821
2674823
2674824
2674825
2674827
2674828
2674829
2674830
2674831
2674832
2674833
2674834
2674835
2674836
2674838
2674839
2674840
2674841
38953_at
8087513
A_23_P170491
GE81571
GO:0003824
GO:0004842
GO:0005515
GO:0005634
GO:0005654
GO:0005694
GO:0005730
GO:0005737
GO:0006281
GO:0006915
GO:0006974
GO:0007165
GO:0010804
GO:0012501
GO:0016567
GO:0016740
GO:0031297
GO:0032688
GO:0042802
GO:0043226
GO:0046872
GO:0048471
GO:0061630
GO:0090734
GO:0106300
GO:0140096
HMNXSV003003933
ILMN_1715540
TC03001419.hg
U77845_at
g5032194_3p_at
Participates
as a candidate of
E3 ligases in proteasomal degradation [cytosol] (Homo sapiens)
Inferred To
nopo [cytosol]
(Drosophila melanogaster)
TRAIP [cytosol]
(Bos taurus)
TRAIP [cytosol]
(Canis familiaris)
TRAIP [cytosol]
(Gallus gallus)
TRAIP [cytosol]
(Sus scrofa)
Traip [cytosol]
(Mus musculus)
Traip [cytosol]
(Rattus norvegicus)
trul-1 [cytosol]
(Caenorhabditis elegans)
traip [cytosol]
(Danio rerio)
traip [cytosol]
(Xenopus tropicalis)
Cross References
RefSeq
NP_005870.2
ENSEMBL
ENSP00000328203
,
ENST00000331456
OpenTargets
ENSG00000183763
HPA
ENSG00000183763-TRAIP
PRO
Q9BWF2
Pharos - Targets
Q9BWF2
GlyGen
Q9BWF2
Orphanet
TRAIP
PDB
4ZTD
Interactors (1)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:O15160 POLR1C
2
POLR1C [cytosol]
(R-HSA-1964454)
POLR1C [nucleoplasm]
(R-HSA-63498)
0.556
3
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