Reactome | BTN2A1 [plasma membrane]

BTN2A1 [plasma membrane]

Stable Identifier

R-HSA-8851994

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

plasma membrane

Synonyms

Butyrophilin subfamily 2 member A1, BT2A1_HUMAN

Locations in the PathwayBrowser for interactor UniProt:P20036 HLA-DPA1

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External Reference Information

External Reference

UniProt:Q7KYR7 BTN2A1

Gene Names

BTN2A1, BT2.1, BTF1

Chain

signal peptide:1-28, chain:29-527

Reference Genes

COSMIC (genes):BTN2A1 Q7KYR74

dbSNP Gene:11120 Q7KYR74

ENSEMBL:ENSG00000112763 BTN2A1

Participates

as a component of

BTN2A1:CD209 [plasma membrane] (Homo sapiens)

as an input of

BTN2A1 binds DC-SIGN (Homo sapiens)

Inferred To

Homologues of BTN2A1 [plasma membrane] (Xenopus tropicalis)

LOC101731445 [plasma membrane] (Xenopus tropicalis)

BTN2A1 [plasma membrane] (Gallus gallus)

LOC100495695 [plasma membrane] (Xenopus tropicalis)

LOC100486763 [plasma membrane] (Xenopus tropicalis)

Btn2a2 [plasma membrane] (Mus musculus)

Btn2a2 [plasma membrane] (Rattus norvegicus)

LOC100493151 [plasma membrane] (Xenopus tropicalis)

LOC100492877 [plasma membrane] (Xenopus tropicalis)

LOC100855640 [plasma membrane] (Canis familiaris)

btn1a1l [plasma membrane] (Xenopus tropicalis)

XB5949738 [plasma membrane] (Xenopus tropicalis)

BTN2A2 [plasma membrane] (Bos taurus)

BTN2A2 [plasma membrane] (Sus scrofa)

LOC100496169 [plasma membrane] (Xenopus tropicalis)

LOC100485074 [plasma membrane] (Xenopus tropicalis)

btn2a2 [plasma membrane] (Xenopus tropicalis)

Interactors (18)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:A8MVW0 F1712			0.527	2
UniProt:Q9NZ56 FMN2			0.527	2
UniProt:B0FP48 UPK3L			0.527	2
UniProt:Q8NEN9 PDZD8			0.527	3
UniProt:Q8WVV5 BTN2A2	1	BTN2A2 [plasma membrane] (R-HSA-8851047)	0.527	2
UniProt:Q15042 RAB3GAP1	2	RAB3GAP1 [endoplasmic reticulum membrane] (R-HSA-508581) RAB3GAP1 [cytosol] (R-HSA-8877982)	0.527	2
UniProt:O95470 SGPL1	1	PXLP-SGPL1 [endoplasmic reticulum membrane] (R-HSA-428661)	0.527	2
UniProt:Q5SVS4 KMCP1			0.527	2
UniProt:Q9NV66 TYW1	1	TYW1 [cytoplasm] (R-HSA-6782884)	0.527	3
UniProt:Q8IWF6 DENND6A	1	DENND6A [cytosol] (R-HSA-8876587)	0.527	2
UniProt:Q9H1E5 TMX4			0.527	3
UniProt:P03886 MT-ND1	1	MT-ND1 [mitochondrial inner membrane] (R-HSA-60551)	0.527	2
UniProt:Q9H2G9 BLZF1	1	BLZF1 [Golgi membrane] (R-HSA-2422372)	0.527	2
UniProt:P22059 OSBP	1	OSBP [cytosol] (R-HSA-429725)	0.527	3
UniProt:P29016 CD1B	1	CD1B [plasma membrane] (R-HSA-197793)	0.527	2
UniProt:Q969R8 ITFG2	1	ITFG2 [lysosomal membrane] (R-HSA-9638231)	0.527	2
UniProt:P20036 HLA-DPA1	9	HLA class II histocompatibility antigen, DP alpha chain precursor [plasma membrane] (R-HSA-197586) HLA class II histocompatibility antigen, DP alpha chain precursor [lysosomal membrane] (R-HSA-2130639) HLA class II histocompatibility antigen, DP alpha chain precursor [endocytic vesicle membrane] (R-HSA-2130435) HLA class II histocompatibility antigen, DP alpha chain precursor [clathrin-coated endocytic vesicle membrane] (R-HSA-2130485) HLA class II histocompatibility antigen, DP alpha chain precursor [transport vesicle membrane] (R-HSA-2130648) HLA class II histocompatibility antigen, DP alpha chain precursor [trans-Golgi network membrane] (R-HSA-2130337) HLA class II histocompatibility antigen, DP alpha chain precursor [Golgi membrane] (R-HSA-2214387) HLA class II histocompatibility antigen, DP alpha chain precursor [ER to Golgi transport vesicle membrane] (R-HSA-2130739) HLA class II histocompatibility antigen, DP alpha chain precursor [lumenal side of endoplasmic reticulum membrane] (R-HSA-2130667)	0.527	2
UniProt:A5A3E0 POTEF			0.527	2