UBA1 [nucleoplasm]

Stable Identifier
R-HSA-8852116
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
Synonyms
Ubiquitin-like modifier-activating enzyme 1, UBA1_HUMAN
UBA1 [nucleoplasm] icon
Locations in the PathwayBrowser for interactor UniProt:Q13489 BIRC3
Literature References
PubMed ID Title Journal Year
21816346 Alternative ubiquitin activation/conjugation cascades interact with N-end rule ubiquitin ligases to control degradation of RGS proteins

Gygi, SP, Sowa, ME, Harper, JW, Lee, PC

Mol. Cell 2011
8010951 Nuclear localization of the ubiquitin-activating enzyme, E1, is cell-cycle-dependent

Schwartz, AL, Ciechanover, A, Grenfell, SJ, Handley-Gearhart, PM, Trausch-Azar, JS

Biochem. J. 1994
External Reference Information
External Reference
Gene Names
UBA1, A1S9T, UBE1
Chain
initiator methionine:, chain:2-1058, initiator methionine:
Other Identifiers
11715371_a_at
1268_at
17103024
200964_PM_at
200964_at
3976064
3976068
3976069
3976079
3976080
3976081
3976082
3976083
3976084
3976085
3976086
3976087
3976088
3976090
3976091
3976092
3976093
3976094
3976095
3976097
3976100
3976101
3976103
3976104
3976106
3976108
3976109
3976114
3976116
3976117
3976118
3976119
7317
8167069
A_23_P137209
A_24_P237374
GE57988
GO:0000166
GO:0000792
GO:0003723
GO:0003824
GO:0004839
GO:0005515
GO:0005524
GO:0005576
GO:0005615
GO:0005634
GO:0005654
GO:0005694
GO:0005737
GO:0005739
GO:0005764
GO:0005765
GO:0005768
GO:0005773
GO:0005783
GO:0005829
GO:0006511
GO:0006974
GO:0008641
GO:0010008
GO:0016567
GO:0016874
GO:0030057
GO:0030163
GO:0030867
GO:0031410
GO:0032446
GO:0036211
GO:0043226
GO:0070062
GO:0140096
GO:0140657
HMNXSV003003863
ILMN_1683609
ILMN_1720764
M58028_at
PH_hs_0024681
TC0X000228.hg
g4507762_3p_at
Participates
Other forms of this molecule
Inferred To
Cross References
OpenTargets
GeneCards
ZINC - Substances
ZINC target
PRO
Pharos - Targets
Orphanet
PDB
HMDB Protein
Interactors (14)
Accession #Entities Entities Confidence Score Evidence (IntAct)
 UniProt:Q9UNE7 STUB1  1 0.73 4
 IntAct:EBI-4399559 UBIQ      0.667 4
 UniProt:Q96FW1 OTUB1  2 0.666 4
 UniProt:Q13489 BIRC3  3 0.59 2
 UniProt:P42858 HTT  1 0.556 3
 UniProt:O00308 WWP2  1 0.556 3
 UniProt:Q9BUZ4 TRAF4      0.556 3
 UniProt:Q9H2C0 GAN  1 0.527 3
 UniProt:Q13618 CUL3  3 0.527 2
 UniProt:P57078 RIPK4      0.527 2
 UniProt:Q9UBF1 MAGC2      0.525 2
 UniProt:P61088 UBE2N  5 0.508 2
 UniProt:Q76353 Q76353      0.499 2
 UniProt:P13569 CFTR  17 0.483 8
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