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GTSE1 binds PLK1
Stable Identifier
R-HSA-8852324
Type
Reaction [binding]
Species
Homo sapiens
Compartment
cytosol
ReviewStatus
5/5
Locations in the PathwayBrowser
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Cell Cycle (Homo sapiens)
Cell Cycle, Mitotic (Homo sapiens)
Mitotic G2-G2/M phases (Homo sapiens)
G2/M Transition (Homo sapiens)
The role of GTSE1 in G2/M progression after G2 checkpoint (Homo sapiens)
GTSE1 binds PLK1 (Homo sapiens)
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The layout of this reaction may differ from that in the pathway view due to the constraints in pathway layout
GTSE1 binds PLK1. The two proteins co-localize on centrosomes from G2 phase to prophase, but not after metaphase (Liu et al. 2010).
Literature References
PubMed ID
Title
Journal
Year
20577264
Polo-like kinase 1 phosphorylation of G2 and S-phase-expressed 1 protein is essential for p53 inactivation during G2 checkpoint recovery
Liu, XS
,
Song, B
,
Li, H
,
Liu, X
EMBO Rep.
2010
Participants
Input
GTSE1 [cytosol]
(Homo sapiens)
p-T210-PLK1 [cytosol]
(Homo sapiens)
Output
GTSE1:p-T210-PLK1 [cytosol]
(Homo sapiens)
Participates
as an event of
The role of GTSE1 in G2/M progression after G2 checkpoint (Homo sapiens)
Orthologous Events
GTSE1 binds PLK1 (Bos taurus)
GTSE1 binds PLK1 (Canis familiaris)
GTSE1 binds PLK1 (Danio rerio)
GTSE1 binds PLK1 (Gallus gallus)
GTSE1 binds PLK1 (Mus musculus)
GTSE1 binds PLK1 (Rattus norvegicus)
GTSE1 binds PLK1 (Sus scrofa)
GTSE1 binds PLK1 (Xenopus tropicalis)
Authored
Orlic-Milacic, M (2016-01-15)
Reviewed
Bird, AW (2016-01-22)
Created
Orlic-Milacic, M (2016-01-15)
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