Reactome | FKBPL [cytosol]

FKBPL [cytosol]

Stable Identifier

R-HSA-8852374

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

cytosol

Synonyms

FK506-binding protein-like, WAF-1/CIP1 stabilizing protein 39, WISp39, DIR1, NG7

Locations in the PathwayBrowser for interactor UniProt:Q96EP0 RNF31

Expand all

Cell Cycle (Homo sapiens)

- Cell Cycle, Mitotic (Homo sapiens)
  - Mitotic G2-G2/M phases (Homo sapiens)
    - G2/M Transition (Homo sapiens)
      - The role of GTSE1 in G2/M progression after G2 checkpoint (Homo sapiens)
        
        GTSE1 binds CDKN1A (Homo sapiens)
        
        FKBPL [cytosol] (Homo sapiens)

External Reference Information

External Reference

UniProt:Q9UIM3 FKBPL

Gene Names

FKBPL, DIR1, NG7

Chain

chain:1-349

Reference Genes

BioGPS Gene:63943 FKBPL

COSMIC (genes):FKBPL FKBPL

CTD Gene:63943 FKBPL

dbSNP Gene:63943 FKBPL

ENSEMBL:ENSG00000204315 FKBPL

HGNC:13949 FKBPL

KEGG:hsa:63943 FKBPL

Monarch:63943 FKBPL

NCBI Gene:63943 FKBPL

UCSC:Q9UIM3 FKBPL

Reference Transcript

RefSeq:NM_022110.3 FKBPL

Other Identifiers

11720164_at

11757996_s_at

17017720

17029555

17032343

17037047

219187_PM_at

219187_at

2949761

2949762

2949763

2949764

2949765

2949766

2949768

52880_at

63943

8125316

8178749

A_23_P70566

GE61881

GO:0003755

GO:0003824

GO:0005515

GO:0005576

GO:0005829

GO:0009314

GO:0016853

GO:0045765

GO:0140096

GO:1905553

HMNXSV003011144

ILMN_1791052

PH_hs_0005507

TC06001559.hg

TC6_cox_hap2000184.hg

TC6_dbb_hap3000175.hg

TC6_mcf_hap5000159.hg

g11545822_3p_at

Participates

as a component of

GTSE1:CDKN1A:FKBPL:HSP90 [cytosol] (Homo sapiens)

as an input of

GTSE1 binds CDKN1A (Homo sapiens)

Inferred To

AIP [cytosol] (Gallus gallus)

FKBPL [cytosol] (Sus scrofa)

Fkbpl [cytosol] (Mus musculus)

Fkbpl [cytosol] (Rattus norvegicus)

Cross References

RefSeq

NP_071393.2

Guide to Pharmacology - Targets

3178

ENSEMBL

ENST00000425378, ENST00000443350, ENST00000375156, ENSP00000397530, ENST00000456854, ENSP00000364298, ENSP00000412439, ENSP00000398812

OpenTargets

ENSG00000204315

HPA

ENSG00000204315-FKBPL

PRO

Q9UIM3

Pharos - Targets

Q9UIM3

Interactors (9)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:Q8WVL7 ANR49			0.821	8
UniProt:P49674 CSNK1E	2	CSNK1E [cytosol] (R-HSA-205877) CSNK1E [nucleoplasm] (R-HSA-421306)	0.643	4
UniProt:Q13137 CACO2			0.556	3
UniProt:P48730 CSNK1D	3	CSNK1D [nucleoplasm] (R-HSA-421305) CSNK1D [endoplasmic reticulum-Golgi intermediate compartment membrane] (R-HSA-5685717) CSNK1D [cytosol] (R-HSA-380315)	0.527	2
UniProt:P15056 BRAF	20	p-S,T-BRAF [cytosol] (R-HSA-169856) BRAF(1-380)-MACF1(600-7388)fusion [cytosol] (R-HSA-6802402) p-BRAF(1-380)-MACF1(600-7388) fusion [cytosol] (R-HSA-6802536) BRAF E501G [cytosol] (R-HSA-9651132) BRAF D594N [cytosol] (R-HSA-6802299) BRAF D638E [cytosol] (R-HSA-9651125) BRAF G596R [cytosol] (R-HSA-6802385) BRAF D594V [cytosol] (R-HSA-6802305) BRAF G596V [cytosol] (R-HSA-9651138) BRAF G466E [cytosol] (R-HSA-6802374) BRAF D594G [cytosol] (R-HSA-6802295) BRAF L505H [cytosol] (R-HSA-9648845) BRAF F595L [cytosol] (R-HSA-6802316) BRAF L597V [cytosol] (R-HSA-6802397) BRAF G464E [cytosol] (R-HSA-6802369) BRAF N581D [cytosol] (R-HSA-9651152) BRAF E586K [cytosol] (R-HSA-6802308) BRAF V600K [cytosol] (R-HSA-6802502) BRAF A246P [cytosol] (R-HSA-9651123) BRAF G469V [cytosol] (R-HSA-9648620)	0.527	2
UniProt:Q96EP0 RNF31	1	RNF31 [cytosol] (R-HSA-5212660)	0.527	2
UniProt:Q3B7T1 EDRF1			0.527	2
UniProt:Q14651 PLS1	1	PLS1 [cytosol] (R-HSA-9662403)	0.527	2
UniProt:Q9BYM8 RBCK1	1	RBCK1 [cytosol] (R-HSA-976018)	0.527	2

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