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VENTX [nucleoplasm]
Stable Identifier
R-HSA-8853887
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
nucleoplasm
Synonyms
Homeobox protein VENTX, VENT homeobox homolog, VENT-like homeobox protein 2, VENTX2, HPX42B
Locations in the PathwayBrowser for interactor UniProt:Q9C004 SPY4
Expand all
Gene expression (Transcription) (Homo sapiens)
RNA Polymerase II Transcription (Homo sapiens)
Generic Transcription Pathway (Homo sapiens)
Transcriptional Regulation by VENTX (Homo sapiens)
VENTX binds the CDKN2A gene (Homo sapiens)
VENTX [nucleoplasm] (Homo sapiens)
VENTX binds the CSF1R (M-CSF-R) gene promoter (Homo sapiens)
VENTX [nucleoplasm] (Homo sapiens)
VENTX binds the IL6 gene promoter (Homo sapiens)
VENTX [nucleoplasm] (Homo sapiens)
VENTX binds the TP53 gene promoter (Homo sapiens)
VENTX [nucleoplasm] (Homo sapiens)
VENTX disrupts binding of CTNNB1 (beta-catenin) to TCF4 or LEF1 (Homo sapiens)
VENTX [nucleoplasm] (Homo sapiens)
External Reference Information
External Reference
UniProt:O95231 VENTX
Gene Names
VENTX, HPX42B, VENTX2
Chain
chain:1-258
Reference Genes
BioGPS Gene:27287 VENTX
COSMIC (genes):VENTX VENTX
CTD Gene:27287 VENTX
dbSNP Gene:27287 VENTX
ENSEMBL:ENSG00000151650 VENTX
ENSEMBL_homo_sapiens_GENE:ENSG00000151650.8 VENTX
HGNC:13639 VENTX
KEGG Gene (Homo sapiens):27287 VENTX
Monarch:27287 VENTX
NCBI Gene:27287 VENTX
OMIM:607158 VENTX
UCSC:O95231 VENTX
Reference Transcript
RefSeq:NM_014468.3 VENTX
Other Identifiers
11732886_at
11732887_x_at
11732888_at
16710900
207376_PM_at
207376_at
27287
3272708
3272709
3272711
3272712
3272713
3272714
3272715
37790_at
7931556
A_23_P419150
GE54602
GO:0000785
GO:0000978
GO:0000981
GO:0001228
GO:0003677
GO:0005515
GO:0005634
GO:0005654
GO:0005694
GO:0006351
GO:0006355
GO:0006357
GO:0043226
GO:0043565
GO:0045944
GO:0140110
GO:1990837
HMNXSV003006876
ILMN_1782352
TC10000951.hg
g7657179_3p_at
Participates
as an input of
VENTX binds the TP53 gene promoter (Homo sapiens)
VENTX binds the CSF1R (M-CSF-R) gene promoter (Homo sapiens)
VENTX binds the IL6 gene promoter (Homo sapiens)
VENTX binds the CDKN2A gene (Homo sapiens)
VENTX disrupts binding of CTNNB1 (beta-catenin) to TCF4 or LEF1 (Homo sapiens)
as a component of
VENTX:TP53 Gene [nucleoplasm] (Homo sapiens)
VENTX:CSF1R Gene [nucleoplasm] (Homo sapiens)
VENTX:IL6 Gene [nucleoplasm] (Homo sapiens)
VENTX:CDKN2A Gene [nucleoplasm] (Homo sapiens)
VENTX:TCF4,LEF1:CCND1 Gene [nucleoplasm] (Homo sapiens)
Inferred To
tab-1 [nucleoplasm]
(Caenorhabditis elegans)
VENTX [nucleoplasm]
(Canis familiaris)
vox [nucleoplasm]
(Danio rerio)
bsh [nucleoplasm]
(Drosophila melanogaster)
hbx2 [nucleoplasm]
(Dictyostelium discoideum)
Cross References
RefSeq
NP_055283.1
OpenTargets
ENSG00000151650
GeneCards
O95231
HPA
ENSG00000151650-VENTX
Ensembl
ENSG00000151650
,
ENSP00000357556
,
ENST00000325980
PRO
O95231
Pharos - Targets
O95231
Interactors (89)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:P59991 KRTAP12-2
1
KRTAP12-2 [cytosol]
(R-HSA-6810271)
0.718
6
UniProt:Q9Y458 TBX22
0.718
6
UniProt:O75553 DAB1
2
DAB1 [cytosol]
(R-HSA-8855236)
p-Y198,220,232-DAB1 [cytosol]
(R-HSA-8855227)
0.666
4
UniProt:Q6P1W5 CA094
0.666
4
UniProt:Q93062 RBPMS
0.666
4
UniProt:P60329 KRTAP12-4
1
KRTAP12-4 [cytosol]
(R-HSA-6810278)
0.666
4
UniProt:Q96SF7 TBX15
0.666
4
UniProt:O76011 KRT34
1
KRT34 [cytosol]
(R-HSA-6809608)
0.601
4
UniProt:Q3LI66 KRTAP6-2
1
KRTAP6-2 [cytosol]
(R-HSA-6810261)
0.556
5
UniProt:Q3LI67 KRTAP6-3
1
KRTAP6-3 [cytosol]
(R-HSA-6810281)
0.556
3
UniProt:Q3LI64 KRTAP6-1
1
KRTAP6-1 [cytosol]
(R-HSA-6810298)
0.556
3
UniProt:P07498 CSN3
1
hC-CSN3 [extracellular region]
(R-HSA-5340152)
0.556
3
UniProt:P40199 CEACAM6
2
GPI-CEACAM6 [plasma membrane]
(R-HSA-204085)
GPI-CEACAM6 [azurophil granule membrane]
(R-HSA-6799133)
0.556
3
UniProt:Q9UHD9 UBQLN2
1
UBQLN2 [cytosol]
(R-HSA-8866007)
0.556
3
UniProt:Q5SWW7 CJ055
0.556
3
UniProt:Q9UF11-2 PLEKHB1
0.556
3
UniProt:Q03060-25 CREM
0.556
3
UniProt:Q8N1L9 BATF2
0.556
3
UniProt:Q9BYR6 KRTAP3-3
1
KRTAP3-3 [cytosol]
(R-HSA-6809859)
0.556
3
UniProt:Q70EL1-9 USP54
0.556
3
IntAct:EBI-22616457 CCSB ORF ID
0.556
5
UniProt:Q5TA45 CPSF3L
1
CPSF3L [nucleoplasm]
(R-HSA-6807411)
0.556
3
UniProt:Q15038 DAZP2
0.556
3
UniProt:Q3LI70 KRTAP19-6
1
KRTAP19-6 [cytosol]
(R-HSA-6810286)
0.556
3
UniProt:Q9NWB1-5 RBFOX1
0.556
3
UniProt:Q9BYR8 KRTAP3-1
1
KRTAP3-1 [cytosol]
(R-HSA-6809868)
0.556
3
UniProt:Q3SYF9 KRTAP19-7
1
KRTAP19-7 [cytosol]
(R-HSA-6810305)
0.556
3
UniProt:Q08AM6 VAC14
3
VAC14 [Golgi membrane]
(R-HSA-1806235)
VAC14 [early endosome membrane]
(R-HSA-1806207)
VAC14 [late endosome membrane]
(R-HSA-1806219)
0.556
3
UniProt:Q7Z782 Q7Z782
0.556
3
UniProt:Q96M29 TEKT5
0.556
3
UniProt:Q03989 ARI5A
0.556
5
UniProt:Q3LHN2 KRTAP19-2
1
KRTAP19-2 [cytosol]
(R-HSA-6810262)
0.556
3
UniProt:P86480 PR20D
0.556
3
UniProt:Q8IUB9 KRTAP19-1
1
KRTAP19-1 [cytosol]
(R-HSA-6810285)
0.556
5
UniProt:Q6UXA7 CF015
0.556
3
UniProt:Q96PV0 SYNGAP1
1
SYNGAP1 [cytosol]
(R-HSA-5658217)
0.556
3
UniProt:P23141-3 CES1
0.556
3
UniProt:O95416 SOX14
0.556
3
UniProt:Q8N1E2 LYG1
0.556
3
UniProt:Q6UY14-3 ADAMTSL4
0.556
3
UniProt:P78358 CTG1B
0.556
5
UniProt:Q5T4B2 GT253
0.556
3
UniProt:Q69YG0 TMM42
0.556
3
UniProt:Q6PEX3 KRTAP26-1
1
KRTAP26-1 [cytosol]
(R-HSA-6810244)
0.556
3
UniProt:P78317 RNF4
2
RNF4 [nucleoplasm]
(R-HSA-5684076)
RNF4 [cytosol]
(R-HSA-975974)
0.556
3
UniProt:Q5T6F2 UBAP2
0.556
3
UniProt:A4D0Q3 A4D0Q3
0.556
3
UniProt:Q9BZE0 GLIS2
0.556
3
UniProt:A8MQ03 CRTP1
0.556
3
UniProt:Q15645 PCH2
0.556
3
UniProt:Q8IUC2 KRTAP8-1
1
KRTAP8-1 [cytosol]
(R-HSA-6810288)
0.556
3
UniProt:Q8IUC1 KRTAP11-1
1
KRTAP11-1 [cytosol]
(R-HSA-6810294)
0.556
3
UniProt:Q99732 LITAF
0.556
3
IntAct:EBI-22384931 CCSB ORF ID
0.556
3
UniProt:Q9BQY4 RHXF2
0.556
3
UniProt:Q01974 ROR2
2
ROR2 [plasma membrane]
(R-HSA-197731)
ROR2 [clathrin-coated endocytic vesicle membrane]
(R-HSA-5140729)
0.556
3
UniProt:Q9NZC7-5 WWOX
0.556
5
UniProt:Q9C004 SPY4
0.556
3
UniProt:Q7KZS0 Q7KZS0
0.556
3
UniProt:hCG_2003792 A0A024R5S0
0.556
3
UniProt:Q96LW2 KS6R
0.556
3
UniProt:Q5BKX5-3 ACTMAP
0.556
3
UniProt:P78424 PO6F2
0.556
3
UniProt:Q6RSH7 VHLL
0.556
3
UniProt:Q16348 S15A2
0.556
3
UniProt:P27918 CFP
6
CFP [extracellular region]
(R-HSA-173751)
CFP [tertiary granule lumen]
(R-HSA-6800993)
CFP [specific granule lumen]
(R-HSA-6799522)
O-fuc-CFP [endoplasmic reticulum lumen]
(R-HSA-5173204)
glc-fuc-CFP [endoplasmic reticulum lumen]
(R-HSA-5173137)
CFP [endoplasmic reticulum lumen]
(R-HSA-5173244)
0.556
5
IntAct:EBI-23202138 CCSB ORF ID
0.556
5
UniProt:A1E959 ODAM
1
ODAM [extracellular region]
(R-HSA-977149)
0.556
3
IntAct:EBI-22461217 CCSB ORF ID
0.556
3
UniProt:Q8NFV4-4 ABHD11
0.556
3
UniProt:P31273 HOXC8
1
HOXC8 [nucleoplasm]
(R-HSA-3222311)
0.556
3
UniProt:Q53HV7-2 SMUG1
0.556
3
UniProt:Q6UXX5 ITIH6
0.556
3
UniProt:A0A0C4DGF1 A0A0C4DGF1
0.556
5
UniProt:O14503 BHLHE40
1
BHLHE40 [nucleoplasm]
(R-HSA-879741)
0.556
3
UniProt:Q9Y5V3 MAGED1
1
MAGED1 [cytosol]
(R-HSA-196002)
0.556
3
IntAct:EBI-16435576 CCSB ORF ID
0.556
3
UniProt:Q9NVL1-2 FAM86C1P
0.556
3
UniProt:Q86WV8 Q86WV8
0.556
3
UniProt:O60806 TBX19
0.556
3
UniProt:A1KXE4-2 FAM168B
0.556
3
UniProt:Q9BZM2-2 PLA2G2F
0.556
3
UniProt:Q9BRT3 MIEN1
0.556
3
UniProt:P60410 KRTAP10-8
1
KRTAP10-8 [cytosol]
(R-HSA-6810301)
0.556
3
UniProt:Q3LI59 KRTAP21-2
1
KRTAP21-2 [cytosol]
(R-HSA-6810245)
0.556
3
UniProt:P15289 ARSA
9
ARSA(19-444) [extracellular region]
(R-HSA-6806192)
ARSA(448-507) [extracellular region]
(R-HSA-6806249)
ARSA(19-444) [azurophil granule lumen]
(R-HSA-6798776)
ARSA(448-507) [azurophil granule lumen]
(R-HSA-6798775)
ARSA(448-507) [lysosomal lumen]
(R-HSA-1606798)
OxA-ARSA(19-444) [lysosomal lumen]
(R-HSA-508497)
OxA-ARSA(19-444) [endoplasmic reticulum lumen]
(R-HSA-1614359)
ARSA(19-444) [endoplasmic reticulum lumen]
(R-HSA-1614334)
ARSA(448-507) [endoplasmic reticulum lumen]
(R-HSA-1614307)
0.556
3
UniProt:Q04724 TLE1
2
Ub-TLE1 [nucleoplasm]
(R-HSA-3322369)
TLE1 [nucleoplasm]
(R-HSA-212327)
0.547
2
UniProt:Q08117 TLE5
1
AES [nucleoplasm]
(R-HSA-4648963)
0.527
2
UniProt:Q93062-3 RBPMS
0.488
2
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