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TCF7L2,LEF1 [nucleoplasm]
Stable Identifier
R-HSA-8853943
Type
Set [DefinedSet]
Species
Homo sapiens
Compartment
nucleoplasm
Synonyms
TCF4,LEF1
Locations in the PathwayBrowser
Expand all
Gene expression (Transcription) (Homo sapiens)
RNA Polymerase II Transcription (Homo sapiens)
Generic Transcription Pathway (Homo sapiens)
Transcriptional Regulation by VENTX (Homo sapiens)
Expression of CCND1 is stimulated by CTNNB1:TCF4,LEF1 and inhibited by VENTX:TCF4,LEF1 (Homo sapiens)
CTNNB1:TCF7L2,LEF1 [nucleoplasm] (Homo sapiens)
TCF7L2,LEF1 [nucleoplasm] (Homo sapiens)
CTNNB1:TCF7L2,LEF1:CCND1 Gene [nucleoplasm] (Homo sapiens)
CTNNB1:TCF7L2,LEF1 [nucleoplasm] (Homo sapiens)
TCF7L2,LEF1 [nucleoplasm] (Homo sapiens)
TCF7L2,LEF1 [nucleoplasm] (Homo sapiens)
VENTX:TCF4,LEF1:CCND1 Gene [nucleoplasm] (Homo sapiens)
TCF7L2,LEF1 [nucleoplasm] (Homo sapiens)
VENTX disrupts binding of CTNNB1 (beta-catenin) to TCF4 or LEF1 (Homo sapiens)
CTNNB1:TCF7L2,LEF1:CCND1 Gene [nucleoplasm] (Homo sapiens)
CTNNB1:TCF7L2,LEF1 [nucleoplasm] (Homo sapiens)
TCF7L2,LEF1 [nucleoplasm] (Homo sapiens)
VENTX:TCF4,LEF1:CCND1 Gene [nucleoplasm] (Homo sapiens)
TCF7L2,LEF1 [nucleoplasm] (Homo sapiens)
Transcriptional regulation by RUNX3 (Homo sapiens)
RUNX3 regulates WNT signaling (Homo sapiens)
CTNNB1:TCF7L2,LEF1 binds the CCND1 gene promoter (Homo sapiens)
CTNNB1:TCF7L2,LEF1 [nucleoplasm] (Homo sapiens)
TCF7L2,LEF1 [nucleoplasm] (Homo sapiens)
CTNNB1:TCF7L2,LEF1:CCND1 Gene [nucleoplasm] (Homo sapiens)
CTNNB1:TCF7L2,LEF1 [nucleoplasm] (Homo sapiens)
TCF7L2,LEF1 [nucleoplasm] (Homo sapiens)
Expression of CCND1 is stimulated by CTNNB1:TCF4,LEF1 (Homo sapiens)
CTNNB1:TCF7L2,LEF1 [nucleoplasm] (Homo sapiens)
TCF7L2,LEF1 [nucleoplasm] (Homo sapiens)
CTNNB1:TCF7L2,LEF1:CCND1 Gene [nucleoplasm] (Homo sapiens)
CTNNB1:TCF7L2,LEF1 [nucleoplasm] (Homo sapiens)
TCF7L2,LEF1 [nucleoplasm] (Homo sapiens)
Signal Transduction (Homo sapiens)
Signaling by WNT (Homo sapiens)
Beta-catenin independent WNT signaling (Homo sapiens)
Ca2+ pathway (Homo sapiens)
NLK phosphorylates TCF/LEF (Homo sapiens)
TCF/LEF:CTNNB1 [nucleoplasm] (Homo sapiens)
TCF7L2,LEF1 [nucleoplasm] (Homo sapiens)
Participants
members
LEF1 [nucleoplasm]
(Homo sapiens)
TCF7L2 [nucleoplasm]
(Homo sapiens)
Participates
as a component of
TCF/LEF:CTNNB1 [nucleoplasm] (Homo sapiens)
VENTX:TCF4,LEF1:CCND1 Gene [nucleoplasm] (Homo sapiens)
CTNNB1:TCF7L2,LEF1 [nucleoplasm] (Homo sapiens)
Inferred To
pan [nucleoplasm]
(Drosophila melanogaster)
lef1 [nucleoplasm]
(Danio rerio)
TCF/LEF [nucleoplasm]
(Bos taurus)
TCF/LEF [nucleoplasm]
(Canis familiaris)
TCF/LEF [nucleoplasm]
(Gallus gallus)
TCF/LEF [nucleoplasm]
(Mus musculus)
TCF/LEF [nucleoplasm]
(Rattus norvegicus)
TCF/LEF [nucleoplasm]
(Sus scrofa)
pop-1 [nucleoplasm]
(Caenorhabditis elegans)
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