RET can bind FRS2, via phosphotyrosine-1062 (p-Y1062) (Kurokawa et al. 2001, Meillo et al. 2001). FRS2 competes with SHC1 for p-Y1062 binding (Lundgren et al. 2006). RET has been reported to associate with FRS2, instead of SHC1, when associated with lipid rafts (Paratcha et al. 2001).
Kurokawa, K, Murakami, H, Takahashi, M, Kawai, K, Hayashi, H, Iwashita, T
Schlessinger, J, Hadari, YR, Melillo, RM, Ong, SH, Billaud, M, Santoro, M, Lax, I, Fusco, A
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