Reactome | HMMR [cytosol]

HMMR [cytosol]

Stable Identifier

R-HSA-8861624

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

cytosol

Synonyms

Hyaluronan mediated motility receptor, HMMR_HUMAN, RHAMM

Locations in the PathwayBrowser

Expand all

External Reference Information

External Reference

UniProt:O75330 HMMR

Gene Names

HMMR, IHABP, RHAMM

Chain

chain:1-724

Reference Genes

BioGPS Gene:3161 HMMR

COSMIC (genes):HMMR HMMR

CTD Gene:3161 HMMR

dbSNP Gene:3161 HMMR

ENSEMBL:ENSG00000072571 HMMR

ENSEMBL_homo_sapiens_GENE:ENSG00000072571.20 HMMR

HGNC:5012 HMMR

KEGG Gene (Homo sapiens):3161 HMMR

Monarch:3161 HMMR

NCBI Gene:3161 HMMR

OMIM:600936 HMMR

UCSC:O75330 HMMR

Reference Transcript

Other Identifiers

11720141_a_at

11737174_a_at

11741032_a_at

11758089_s_at

16991859

207165_PM_at

207165_at

209709_PM_s_at

209709_s_at

2838658

2838659

2838660

2838661

2838662

2838664

2838666

2838667

2838668

2838671

2838672

2838673

2838674

2838675

2838676

2838677

2838678

2838679

2838680

2838681

2838682

2838683

2838684

2838685

3161

36863_at

8109712

A_14_P117078

A_14_P134101

A_23_P70007

GE81805

GO:0005515

GO:0005540

GO:0005737

GO:0005813

GO:0005815

GO:0005819

GO:0005829

GO:0005856

GO:0005886

GO:0006898

GO:0009986

GO:0015630

GO:0016020

GO:0016192

GO:0030214

GO:0038024

GO:0043226

GO:1901135

HMNXSV003027124

ILMN_1781942

ILMN_2409220

PH_hs_0004174

TC05000907.hg

U29343_at

g2959555_3p_a_at

Participates

as a component of

as an input of

TPX2 binds AURKA at centrosomes (Homo sapiens)

Other forms of this molecule

HMMR [plasma membrane]

Inferred To

Hmmr [cytosol] (Mus musculus)

Ghost homologue of HMMR [cytosol] (Rattus norvegicus)

HMMR [cytosol] (Bos taurus)

HMMR [cytosol] (Canis familiaris)

HMMR [cytosol] (Gallus gallus)

HMMR [cytosol] (Sus scrofa)

hmmr [cytosol] (Xenopus tropicalis)

Cross References

RefSeq

NP_001136029.1, NP_036616.2, NP_001136028.1, NP_036617.2

OpenTargets

ENSG00000072571

GeneCards

O75330

HPA

ENSG00000072571-HMMR

Ensembl

ENST00000432118, ENST00000393915, ENSG00000072571, ENSP00000402673, ENSP00000351554, ENST00000358715, ENST00000353866, ENSP00000185942, ENSP00000377492

PRO

O75330

Pharos - Targets

O75330

HMDB Protein

HMDBP10894

Interactors (9)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:P48729 CSNK1A1	2	CSNK1A1 [cytosol] (R-HSA-195263) CSNK1A1 [cilium] (R-HSA-5632507)	0.725	4
UniProt:Q8NDC4 MORN4			0.666	4
UniProt:Q9H4H8 FAM83D	1	FAM83D [cytosol] (R-HSA-9852722)	0.564	3
UniProt:P63167 DYNLL1	6	DYNLL1 [ciliary tip] (R-HSA-5625335) DYNLL1 [cilium] (R-HSA-5624863) DYNLL1 [ficolin-1-rich granule membrane] (R-HSA-6801518) DYNLL1 [tertiary granule membrane] (R-HSA-6801482) DYNLL1 [plasma membrane] (R-HSA-54017) DYNLL1 [cytosol] (R-HSA-387105)	0.527	2
UniProt:Q96FJ2 DYNLL2	4	DYNLL2 [cytosol] (R-HSA-2029024) DYNLL2 [plasma membrane] (R-HSA-140527) DYNLL2 [cilium] (R-HSA-5624865) DYNLL2 [ciliary tip] (R-HSA-5625337)	0.527	2
UniProt:P28482 MAPK1	18	MAPK1 [endoplasmic reticulum lumen] (R-HSA-9636293) MAPK1 [ficolin-1-rich granule lumen] (R-HSA-6800964) MAPK1 [extracellular region] (R-HSA-6806250) MAPK1 [azurophil granule lumen] (R-HSA-6799225) p-T185,Y187 MAPK1 E322V [cytosol] (R-HSA-9652797) p-T185,Y187 MAPK1 E322K [cytosol] (R-HSA-9652175) p-T185,Y187 MAPK1 E81K [cytosol] (R-HSA-9652799) p-T185,Y187 MAPK1 S142L [cytosol] (R-HSA-9652808) p-T185,Y187 MAPK1 P58L [cytosol] (R-HSA-9652806) p-T185,Y187 MAPK1 D321V [cytosol] (R-HSA-9652791) p-T185,Y187 MAPK1 D321N [cytosol] (R-HSA-9652785) p-T185,Y187 MAPK1 E322A [cytosol] (R-HSA-9652794) p-T185,Y187 MAPK1 P58G [cytosol] (R-HSA-9652802) p-T185-MAPK1 [cytosol] (R-HSA-9635773) MAPK1 [nucleoplasm] (R-HSA-199960) MAPK1 [cytosol] (R-HSA-59282) p-T185,Y187-MAPK1 [cytosol] (R-HSA-109853) p-T185,Y187-MAPK1 [nucleoplasm] (R-HSA-112354)	0.527	2
UniProt:P13569 CFTR	17	PolyUb-CFTR [clathrin-coated endocytic vesicle membrane] (R-HSA-8869104) PolyUb-CFTR [plasma membrane] (R-HSA-8867595) CFTR [lysosomal membrane] (R-HSA-5627279) CFTR [Golgi-associated vesicle membrane] (R-HSA-5627079) CFTR [endosome membrane] (R-HSA-6782965) PolyUb-CFTR [endosome membrane] (R-HSA-6782976) CFTR F508del [endoplasmic reticulum membrane] (R-HSA-8866834) ub-CFTR F508del [cytosol] (R-HSA-8866838) ub-CFTR F508del [endoplasmic reticulum membrane] (R-HSA-8866842) CFTR G542* [plasma membrane] (R-HSA-5678986) CFTR G551D [plasma membrane] (R-HSA-5678977) CFTR W1282* [plasma membrane] (R-HSA-5678976) CFTR F508del [plasma membrane] (R-HSA-5678978) CFTR N1303K [plasma membrane] (R-HSA-5678983) CFTR [plasma membrane] (R-HSA-383188) CFTR [endoplasmic reticulum membrane] (R-HSA-8866837) misfolded CFTR [endoplasmic reticulum membrane] (R-HSA-8868730)	0.519	7
UniProt:Q9ULW0 TPX2	2	TPX2 [cytosol] (R-HSA-8853407) TPX2 [nucleoplasm] (R-HSA-2564700)	0.499	5
UniProt:P38398 BRCA1	20	polySUMO2,3-BRCA1 [nucleoplasm] (R-HSA-2997624) monoSUMO1-K109-BRCA1 [nucleoplasm] (R-HSA-2997644) BRCA1 M1411T [nucleoplasm] (R-HSA-9702140) BRCA1 M1400V [nucleoplasm] (R-HSA-9701202) BRCA1 L1407P [nucleoplasm] (R-HSA-9702135) BRCA1 Y777* [nucleoplasm] (R-HSA-9702765) BRCA1 S1009* [nucleoplasm] (R-HSA-9702755) BRCA1 P724Lfs12 [nucleoplasm] (R-HSA-9703778) BRCA1 S451 [nucleoplasm] (R-HSA-9702754) BRCA1 S864* [nucleoplasm] (R-HSA-9702752) BRCA1 P897Kfs5 [nucleoplasm] (R-HSA-9703782) BRCA1 N555Kfs17 [nucleoplasm] (R-HSA-9703781) BRCA1 Y1127Sfs6 [nucleoplasm] (R-HSA-9703780) BRCA1 S886Cfs16 [nucleoplasm] (R-HSA-9703802) BRCA1 V83Cfs2 [nucleoplasm] (R-HSA-9703800) BRCA1 T464Pfs11 [nucleoplasm] (R-HSA-9703807) BRCA1 G813Dfs2 [nucleoplasm] (R-HSA-9703549) BRCA1 V340Gfs6 [nucleoplasm] (R-HSA-9703804) BRCA1 Y655* [nucleoplasm] (R-HSA-9702769) BRCA1 W372* [nucleoplasm] (R-HSA-9702768)	0.499	4

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