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P2RX3 [plasma membrane]
Stable Identifier
R-HSA-8861879
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
plasma membrane
Synonyms
P2X purinoceptor 3, P2RX3_HUMAN
Locations in the PathwayBrowser
Expand all
Hemostasis (Homo sapiens)
Platelet homeostasis (Homo sapiens)
Binding of ATP to P2X receptors (Homo sapiens)
P2RX receptors [plasma membrane] (Homo sapiens)
P2RX3 [plasma membrane] (Homo sapiens)
P2X purinoreceptors:ATP [plasma membrane] (Homo sapiens)
P2RX receptors [plasma membrane] (Homo sapiens)
P2RX3 [plasma membrane] (Homo sapiens)
Platelet calcium homeostasis (Homo sapiens)
Elevation of cytosolic Ca2+ levels (Homo sapiens)
P2X1-mediated entry of Ca++ from plasma (Homo sapiens)
P2X purinoreceptors:ATP [plasma membrane] (Homo sapiens)
P2RX receptors [plasma membrane] (Homo sapiens)
P2RX3 [plasma membrane] (Homo sapiens)
External Reference Information
External Reference
UniProt:P56373 P2RX3
Gene Names
P2RX3
Chain
chain:1-397
Reference Genes
BioGPS Gene:5024 P2RX3
COSMIC (genes):P2RX3 P2RX3
CTD Gene:5024 P2RX3
dbSNP Gene:5024 P2RX3
ENSEMBL:ENSG00000109991 P2RX3
ENSEMBL_homo_sapiens_GENE:ENSG00000109991.10 P2RX3
HGNC:8534 P2RX3
KEGG Gene (Homo sapiens):5024 P2RX3
Monarch:5024 P2RX3
NCBI Gene:5024 P2RX3
OMIM:600843 P2RX3
UCSC:P56373 P2RX3
Reference Transcript
RefSeq:XM_011545070.2 P2RX3
RefSeq:NM_002559.3 P2RX3
RefSeq:XM_011545069.2 P2RX3
Other Identifiers
11735800_at
16724818
208338_PM_at
208338_at
31733_at
3331218
3331219
3331227
3331229
3331230
3331231
3331233
3331234
3331236
3331240
3331241
3331243
3331244
3331245
3331247
3331248
3331250
3331251
3331252
3331253
44227_at
5024
7940005
A_23_P127721
GE60244
GO:0000166
GO:0001614
GO:0001666
GO:0003012
GO:0004931
GO:0005215
GO:0005216
GO:0005524
GO:0005886
GO:0006811
GO:0006812
GO:0007165
GO:0007268
GO:0007274
GO:0009266
GO:0009408
GO:0009409
GO:0009612
GO:0009743
GO:0010033
GO:0010524
GO:0014832
GO:0015267
GO:0016020
GO:0023052
GO:0030424
GO:0030432
GO:0033198
GO:0034220
GO:0035590
GO:0043005
GO:0043235
GO:0048167
GO:0048266
GO:0050804
GO:0050850
GO:0050877
GO:0050909
GO:0051649
GO:0055085
GO:0060079
GO:0060089
GO:0065003
GO:0070207
GO:0070588
GO:0071318
GO:0098655
GO:0098662
GO:0098685
GO:0098686
GO:0098794
HMNXSV003030910
ILMN_1654997
ILMN_1740263
ILMN_1806186
PH_hs_0022621
TC11000461.hg
Y07683_at
g4505546_3p_at
Participates
as a member of
P2RX receptors [plasma membrane] (Homo sapiens)
Inferred To
p2xC [plasma membrane]
(Dictyostelium discoideum)
Homologues of P2RX3 [plasma membrane]
(Dictyostelium discoideum)
p2xB [plasma membrane]
(Dictyostelium discoideum)
p2xD [plasma membrane]
(Dictyostelium discoideum)
P2RX3 [plasma membrane]
(Bos taurus)
P2RX3 [plasma membrane]
(Canis familiaris)
P2RX3 [plasma membrane]
(Danio rerio)
P2RX3 [plasma membrane]
(Mus musculus)
P2RX3 [plasma membrane]
(Rattus norvegicus)
P2RX3 [plasma membrane]
(Sus scrofa)
p2xA [plasma membrane]
(Dictyostelium discoideum)
p2xE [plasma membrane]
(Dictyostelium discoideum)
Cross References
RefSeq
NP_002550.2
,
XP_011543372.1
,
XP_011543371.1
ZINC - World Drugs
P2RX3_HUMAN
Guide to Pharmacology - Targets
480
OpenTargets
ENSG00000109991
ZINC - Substances
P2RX3_HUMAN
ZINC target
P56373
ZINC - Biogenic
P2RX3_HUMAN
PRO
P56373
PDB
5SVT
,
5SVL
,
5SVK
,
6AH5
,
5YVE
,
5SVJ
,
5SVP
,
5SVR
,
5SVS
,
6AH4
,
5SVM
,
5SVQ
ZINC - Investigational
P2RX3_HUMAN
ZINC - Metabolites
P2RX3_HUMAN
HPA
ENSG00000109991-P2RX3
GeneCards
P56373
Ensembl
ENSP00000263314
,
ENSG00000109991
,
ENST00000263314
Pharos - Targets
P56373
ZINC - Predictions - Purchasable
P2RX3_HUMAN
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