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SYTL4 [platelet alpha granule membrane]
Stable Identifier
R-HSA-8862959
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
platelet alpha granule membrane
Synonyms
Synaptotagmin-like protein 4, SYTL4_HUMAN
Locations in the PathwayBrowser
Expand all
Hemostasis (Homo sapiens)
Platelet activation, signaling and aggregation (Homo sapiens)
Response to elevated platelet cytosolic Ca2+ (Homo sapiens)
Platelet degranulation (Homo sapiens)
Surface deployment of platelet alpha granule membrane components (Homo sapiens)
Platelet alpha granule membrane components that are released on degranulation [platelet alpha granule membrane] (Homo sapiens)
SYTL4 [platelet alpha granule membrane] (Homo sapiens)
External Reference Information
External Reference
UniProt:Q96C24 SYTL4
Gene Names
SYTL4
Chain
chain:1-671
Reference Genes
BioGPS Gene:94121 SYTL4
COSMIC (genes):SYTL4 SYTL4
CTD Gene:94121 SYTL4
dbSNP Gene:94121 SYTL4
ENSEMBL:ENSG00000102362 SYTL4
ENSEMBL_homo_sapiens_GENE:ENSG00000102362.16 SYTL4
HGNC:15588 SYTL4
KEGG Gene (Homo sapiens):94121 SYTL4
Monarch:94121 SYTL4
NCBI Gene:94121 SYTL4
OMIM:300723 SYTL4
UCSC:Q96C24 SYTL4
Reference Transcript
RefSeq:XM_011531068.2 SYTL4
RefSeq:XM_017029971.1 SYTL4
RefSeq:NM_001129896.2 SYTL4
RefSeq:NM_001174068.1 SYTL4
RefSeq:NM_080737.2 SYTL4
RefSeq:XM_005262229.2 SYTL4
Other Identifiers
11730651_a_at
11730652_a_at
1563513_3p_at
1563513_PM_at
1563513_at
17112623
227703_PM_s_at
227703_s_at
4015437
4015439
4015441
4015442
4015444
4015447
4015449
4015450
4015451
4015452
4015453
4015454
4015455
4015456
4015457
4015458
4015459
4015460
4015461
4015462
4015463
4015464
4015465
4015466
4015467
4015468
4015469
4015470
4015473
4015474
58702_at
8173955
94121
A_24_P122337
A_33_P3241651
A_33_P3266730
GE88388
GO:0001778
GO:0005515
GO:0005543
GO:0005768
GO:0005886
GO:0006886
GO:0006887
GO:0008289
GO:0016020
GO:0016192
GO:0023052
GO:0030073
GO:0030141
GO:0030658
GO:0031092
GO:0031267
GO:0031410
GO:0032418
GO:0042043
GO:0042060
GO:0043226
GO:0045921
GO:0046676
GO:0046872
GO:0050714
GO:0061024
GO:0070382
GO:0071985
GO:1905684
HMNXSV003013649
HMNXSV003042113
Hs.247525.1.A1_3p_a_at
Hs2.376981.1.S1_3p_at
Hs2.376981.1.S1_3p_x_at
ILMN_1719599
PH_hs_0024273
PH_hs_0039973
TC0X001209.hg
Participates
as a member of
Platelet alpha granule membrane components that are released on degranulation [platelet alpha granule membrane] (Homo sapiens)
Other forms of this molecule
SYTL4 [plasma membrane]
Inferred To
sytl4 [platelet alpha granule membrane]
(Danio rerio)
sytl4 [platelet alpha granule membrane]
(Xenopus tropicalis)
Sytl4 [platelet alpha granule membrane]
(Mus musculus)
Sytl4 [platelet alpha granule membrane]
(Rattus norvegicus)
SYTL4 [platelet alpha granule membrane]
(Bos taurus)
SYTL4 [platelet alpha granule membrane]
(Canis familiaris)
SYTL4 [platelet alpha granule membrane]
(Dictyostelium discoideum)
SYTL4 [platelet alpha granule membrane]
(Gallus gallus)
SYTL4 [platelet alpha granule membrane]
(Sus scrofa)
btsz [platelet alpha granule membrane]
(Drosophila melanogaster)
Cross References
RefSeq
NP_001167539.1
,
XP_005262286.1
,
NP_542775.2
,
NP_001123368.1
,
XP_016885460.1
,
XP_011529370.1
OpenTargets
ENSG00000102362
GeneCards
Q96C24
HPA
ENSG00000102362-SYTL4
Ensembl
ENSP00000362072
,
ENSP00000362080
,
ENST00000263033
,
ENST00000372981
,
ENST00000685623
,
ENSG00000102362
,
ENSP00000276141
,
ENST00000276141
,
ENSP00000263033
,
ENST00000372989
,
ENSP00000509693
PRO
Q96C24
Pharos - Targets
Q96C24
PDB
5X6T
,
2CSZ
,
3FDW
Interactors (5)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:P51159 RAB27A
5
GGC-RAB27A [cytosol]
(R-HSA-8870427)
RAB27A [cytosol]
(R-HSA-3008674)
GGC-RAB27A [melanosome membrane]
(R-HSA-8877281)
RAB27A [extracellular region]
(R-HSA-6799682)
RAB27A [specific granule lumen]
(R-HSA-6799609)
0.666
5
UniProt:Q86TI0 TBC1D1
2
TBC1D1 [cytoplasmic vesicle membrane]
(R-HSA-1454718)
p-S237-TBC1D1 [cytosol]
(R-HSA-1454673)
0.556
3
UniProt:Q9UGI0 ZRANB1
1
ZRANB1 [cytosol]
(R-HSA-6781939)
0.556
3
UniProt:P61764 STXBP1
2
STXBP1 [cytosol]
(R-HSA-6794256)
STXBP1 [plasma membrane]
(R-HSA-2980862)
0.556
3
UniProt:P20336 RAB3A
9
RAB3A [clathrin-sculpted monoamine transport vesicle membrane]
(R-HSA-372512)
RAB3A [plasma membrane]
(R-HSA-210461)
RAB3A [clathrin-sculpted gamma-aminobutyric acid transport vesicle membrane]
(R-HSA-917743)
RAB3A [clathrin-sculpted glutamate transport vesicle membrane]
(R-HSA-210466)
RAB3A [secretory granule membrane]
(R-HSA-6804968)
RAB3A [clathrin-sculpted acetylcholine transport vesicle membrane]
(R-HSA-379365)
RAB3A [cytosol]
(R-HSA-8870410)
GGC-RAB3A [cytosol]
(R-HSA-8870429)
GGC-RAB3A [secretory granule membrane]
(R-HSA-8875319)
0.527
3
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