CDK5 [nucleoplasm]

Stable Identifier
R-HSA-8863586
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
nucleoplasm
Locations in the PathwayBrowser for interactor UniProt:P50991 CCT4
Expand all
Literature References
PubMed ID Title Journal Year
10500146 Regulation of cyclin-dependent kinase 5 catalytic activity by phosphorylation

Albers, RW, Sharma, M, Sharma, P, Pant, HC, Amin, ND

Proc. Natl. Acad. Sci. U.S.A. 1999
External Reference Information
External Reference
UniProt:Q00535 CDK5
Gene Names
CDK5, CDKN5, PSSALRE
Chain
chain:1-292
Reference Genes
BioGPS Gene:1020 CDK5
COSMIC (genes):CDK5 CDK5
CTD Gene:1020 CDK5
dbSNP Gene:1020 CDK5
ENSEMBL:ENSG00000164885 CDK5
ENSEMBL_homo_sapiens_GENE:ENSG00000164885.13 CDK5
HGNC:1774 CDK5
KEGG Gene (Homo sapiens):1020 CDK5
Monarch:1020 CDK5
NCBI Gene:1020 CDK5
OMIM:123831 CDK5
UCSC:Q00535 CDK5
Reference Transcript
Other Identifiers
1020
11751815_a_at
11754938_a_at
1206_at
17064360
204247_PM_s_at
204247_s_at
3079312
3079314
3079315
3079316
3079317
3079319
3079320
3079321
3079322
3079323
3079324
3079325
3079326
3079328
3079329
3079330
3113884
40549_at
8143850
A_23_P8400
GE57557
GE86263
GO:0000166
GO:0000226
GO:0000307
GO:0001764
GO:0001963
GO:0002039
GO:0003824
GO:0004672
GO:0004674
GO:0004693
GO:0005176
GO:0005515
GO:0005524
GO:0005634
GO:0005654
GO:0005737
GO:0005829
GO:0005856
GO:0005874
GO:0005886
GO:0006351
GO:0006355
GO:0006468
GO:0006886
GO:0006913
GO:0006914
GO:0006915
GO:0007010
GO:0007049
GO:0007155
GO:0007160
GO:0007268
GO:0007399
GO:0007409
GO:0007416
GO:0007519
GO:0008045
GO:0008092
GO:0008306
GO:0008542
GO:0012501
GO:0014044
GO:0014069
GO:0016020
GO:0016079
GO:0016192
GO:0016241
GO:0016301
GO:0016310
GO:0016477
GO:0016533
GO:0016740
GO:0018105
GO:0018107
GO:0019233
GO:0021537
GO:0021549
GO:0021695
GO:0021697
GO:0021766
GO:0021819
GO:0021954
GO:0021987
GO:0022038
GO:0023052
GO:0030027
GO:0030054
GO:0030154
GO:0030175
GO:0030182
GO:0030334
GO:0030424
GO:0030425
GO:0030426
GO:0030517
GO:0030549
GO:0030900
GO:0031175
GO:0031397
GO:0031594
GO:0031914
GO:0032801
GO:0034330
GO:0035249
GO:0035418
GO:0036211
GO:0042220
GO:0042981
GO:0042995
GO:0043005
GO:0043025
GO:0043113
GO:0043125
GO:0043204
GO:0043226
GO:0043525
GO:0045202
GO:0045786
GO:0045861
GO:0045892
GO:0045956
GO:0046826
GO:0048148
GO:0048156
GO:0048167
GO:0048488
GO:0048489
GO:0048511
GO:0048675
GO:0048709
GO:0048813
GO:0048856
GO:0048870
GO:0050321
GO:0050877
GO:0051301
GO:0051402
GO:0051649
GO:0051726
GO:0051879
GO:0051966
GO:0060078
GO:0060079
GO:0061001
GO:0070509
GO:0072659
GO:0090314
GO:0098772
GO:0098793
GO:0106310
GO:0140096
GO:1903076
GO:1903421
GO:1904646
HMNXSV003006567
ILMN_1781987
PH_hs_0029292
PH_hs_0031953
TC07002027.hg
X66364_at
g4826674_3p_at
Participates
as a component of
This entity regulates
Negatively
Positively
Other forms of this molecule
p-Y15,S159-CDK5 [nucleoplasm]
CDK5 [cytosol]
p-Y15-CDK5 [cytosol]
Inferred To
CDK5 [nucleoplasm] (Bos taurus)
CDK5 [nucleoplasm] (Canis familiaris)
CDK5 [nucleoplasm] (Drosophila melanogaster)
CDK5 [nucleoplasm] (Gallus gallus)
CDK5 [nucleoplasm] (Rattus norvegicus)
CDK5 [nucleoplasm] (Sus scrofa)
Cross References
RefSeq
ZINC - World Drugs
Guide to Pharmacology - Targets
OpenTargets
ZINC - FDA approved
ZINC - Substances
ZINC - Biogenic
ZINC target
PRO
PDB
ZINC - Investigational
ZINC - Metabolites
GeneCards
HPA
Ensembl
Pharos - Targets
ZINC - Predictions - Purchasable
HMDB Protein
Interactors (43)
Accession #Entities Entities Confidence Score Evidence (IntAct)
 UniProt:P30279 CCND2  2 0.959 18
 UniProt:Q15078 CDK5R1  4 0.94 15
 UniProt:P46527 CDKN1B  8 0.94 14
 UniProt:Q8TDN4 CABLES1  2 0.886 8
 UniProt:P14635 CCNB1  4 0.886 8
 UniProt:P30281 CCND3  2 0.882 12
 UniProt:P38936 CDKN1A  5 0.839 7
 UniProt:Q86YS7 C2CD5  2 0.837 7
 UniProt:O43427 FIBP      0.788 8
 UniProt:Q14094 CCNI      0.75 6
 UniProt:Q00526 CDK3      0.725 5
 UniProt:Q12767 ERMA      0.725 4
 UniProt:Q9BTV7 CABLES2  1 0.725 4
 UniProt:A6NLX3 SPDE4      0.666 4
 UniProt:Q99832 CCT7  1 0.643 3
 UniProt:P49368 CCT3  1 0.643 3
 UniProt:P50990 CCT8  5 0.643 3
 UniProt:P50991 CCT4  1 0.643 3
 UniProt:P24385 CCND1  4 0.643 4
 UniProt:P20248 CCNA2  3 0.643 4
 UniProt:P61158 ACTR3  1 0.556 3
 UniProt:O60260-5 PRKN      0.556 3
 UniProt:P20226 TBP  1 0.556 3
 UniProt:Q5MJ70 SPDYA      0.556 3
 UniProt:P05067 APP  20 0.556 3
 UniProt:P23560-2 BDNF      0.556 3
 UniProt:Q9UJC3 HOOK1      0.556 3
 UniProt:Q6FHY5 Q6FHY5      0.556 3
 UniProt:Q9Y6R0 NUMBL      0.556 3
 UniProt:P62937 PPIA  5 0.556 3
 UniProt:Q16543 CDC37  1 0.547 2
 UniProt:P78371 CCT2  3 0.527 2
 UniProt:Q9BV87 CNPD1      0.527 3
 UniProt:P24864 CCNE1  3 0.527 2
 UniProt:Q6ZMN8 CCNI2      0.527 2
 UniProt:P40227 CCT6A  1 0.527 2
 UniProt:P17987 TCP1  1 0.527 2
 UniProt:Q9C098 DCLK3      0.527 2
 UniProt:P10636-8 MAPT  3 0.527 4
 UniProt:Q8IZL9 CDK20      0.527 2
 UniProt:P48643 CCT5  1 0.527 2
 UniProt:P37231-2 PPARG  1 0.508 2
 UniProt:P09936 UCHL1  1 0.499 2
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