TFAP2A,TFAP2C homodimers stimulate CGA gene expression

Stable Identifier
R-HSA-8864433
Type
Reaction [omitted]
Species
Homo sapiens
Compartment
ReviewStatus
5/5
Locations in the PathwayBrowser
General
SVG |   | PPTX  | SBGN
Click the image above or here to open this reaction in the Pathway Browser
The layout of this reaction may differ from that in the pathway view due to the constraints in pathway layout
Homodimers of AP-2 family transcription factors TFAP2A (AP-2 alpha) and TFAP2C (AP-2 gamma) directly stimulate CGA (chorionic gonadotropin alpha) transcription by binding to the CGA promoter (Johnson et al. 1997, LiCalsi et al. 2000).
Literature References
PubMed ID Title Journal Year
9182571 Regulation of the human chorionic gonadotropin alpha- and beta-subunit promoters by AP-2

Johnson, W, Albanese, C, Jameson, JL, Pestell, RG, Williams, T, Handwerger, S

J. Biol. Chem. 1997
10648798 AP-2 family members regulate basal and cAMP-induced expression of human chorionic gonadotropin

LiCalsi, C, Fischer, W, Buescher, M, Mellon, PL, Christophe, S, Steger, DJ

Nucleic Acids Res. 2000
Participants
Participates
This event is regulated
Authored
Reviewed
Created
Cite Us!