TFAP2C homodimer binds MYC and KDM5B

Stable Identifier
R-HSA-8865265
Type
Reaction [binding]
Species
Homo sapiens
Compartment
nucleoplasm
ReviewStatus
5/5
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TFAP2C homodimer binds MYC and KDM5B
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TFAP2C (AP-2 gamma) transcription factor homodimer can form a complex with MYC transcription factor and histone demethylase KDM5B (Wong et al. 2012).
Literature References
PubMed ID Title Journal Year
22371483 Histone demethylase KDM5B collaborates with TFAP2C and Myc to repress the cell cycle inhibitor p21(cip) (CDKN1A)

Berlato, C, Hurst, HC, Miranda, F, Wong, PP, Scibetta, AG, Chan, KV

Mol. Cell. Biol. 2012
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Orthologous Events
TFAP2C homodimer binds MYC and KDM5B (Bos taurus)
TFAP2C homodimer binds MYC and KDM5B (Canis familiaris)
TFAP2C homodimer binds MYC and KDM5B (Danio rerio)
TFAP2C homodimer binds MYC and KDM5B (Drosophila melanogaster)
TFAP2C homodimer binds MYC and KDM5B (Gallus gallus)
TFAP2C homodimer binds MYC and KDM5B (Mus musculus)
TFAP2C homodimer binds MYC and KDM5B (Rattus norvegicus)
TFAP2C homodimer binds MYC and KDM5B (Sus scrofa)
Authored
Orlic-Milacic, M  (2016-03-14)
Reviewed
Zarelli, VE  (2016-05-04)
Bogachek, MV  (2016-05-17)
Dawid, IB  (2016-05-04)
Weigel, RJ  (2016-05-17)
Created
Orlic-Milacic, M  (2016-03-21)
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