RUNX1:CBFB binds FOXP3 gene

Stable Identifier
R-HSA-8865547
Type
Reaction [binding]
Species
Homo sapiens
Compartment
ReviewStatus
5/5
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RUNX1, in complex with CBFB, binds to at least two regulatory elements in the promoter of the FOXP3 gene (Kitoh et al. 2009).
Literature References
PubMed ID Title Journal Year
19800266 Indispensable role of the Runx1-Cbfbeta transcription complex for in vivo-suppressive function of FoxP3+ regulatory T cells

Yamaguchi, T, Miyachi, Y, Yaguchi, H, Nomura, T, Sakaguchi, S, Naoe, Y, Kitoh, A, Taniuchi, I, Ohkura, N, Tsukada, T, Kitabayashi, I, Ono, M

Immunity 2009
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