Reactome | RBM17 [nucleoplasm]

RBM17 [nucleoplasm]

Stable Identifier

R-HSA-8865891

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

nucleoplasm

Synonyms

Splicing factor 45, SPF45_HUMAN

Locations in the PathwayBrowser

Expand all

Disease (Homo sapiens)

- Infectious disease (Homo sapiens)
  - Viral Infection Pathways (Homo sapiens)
    - Dengue Virus Infection (Homo sapiens)
      - Dengue Virus-Host Interactions (Homo sapiens)
        
        NS5 interacts with Spliceosome (Homo sapiens)
        
        NS5:Spliceosomal Intermediate C Complex [nucleoplasm] (Homo sapiens)
        
        Spliceosomal Intermediate C Complex [nucleoplasm] (Homo sapiens)
        
        U2 snRNP [nucleoplasm] (Homo sapiens)
        
        RBM17 [nucleoplasm] (Homo sapiens)
        
        Spliceosomal Intermediate C Complex [nucleoplasm] (Homo sapiens)
        
        U2 snRNP [nucleoplasm] (Homo sapiens)
        
        RBM17 [nucleoplasm] (Homo sapiens)

External Reference Information

External Reference

UniProt:Q96I25 RBM17

Gene Names

RBM17, SPF45

Chain

initiator methionine:1, chain:2-401

Reference Genes

BioGPS Gene:84991 RBM17

COSMIC (genes):RBM17 RBM17

CTD Gene:84991 RBM17

dbSNP Gene:84991 RBM17

ENSEMBL:ENSG00000134453 RBM17

HGNC:16944 RBM17

KEGG:hsa:84991 RBM17

Monarch:84991 RBM17

NCBI Gene:84991 RBM17

OMIM:606935 RBM17

UCSC:Q96I25 RBM17

Reference Transcript

Other Identifiers

11721677_a_at

11721678_a_at

11721679_a_at

11733843_a_at

16702147

224780_PM_at

224780_at

224781_PM_s_at

224781_s_at

225751_PM_at

225751_at

3233548

3233549

3233550

3233551

3233552

3233553

3233557

3233558

3233559

3233560

3233561

3233562

3233563

3233564

3233567

3233568

3233570

3233571

3233572

3233573

3233575

3233576

3233577

3233578

3233579

3233580

3233581

3233582

3233583

3233584

3233585

3233586

3233587

3233588

3233589

3617985

3617990

3617991

49221_s_at

56356_at

7926021

84991

A_23_P35645

A_23_P35650

A_23_P423315

GE80333

GE85300

GE86522

GO:0000375

GO:0000380

GO:0000398

GO:0003676

GO:0003723

GO:0005515

GO:0005634

GO:0005654

GO:0005681

GO:0006397

GO:0008380

GO:0016071

GO:0032991

GO:0045292

HMNXSV003034450

Hs.107001.0.S1_3p_a_at

Hs.107001.0.S2_3p_at

Hs.107001.1.S1_3p_at

ILMN_1781906

PH_hs_0005949

TC10000052.hg

Participates

as a component of

Inferred To

rbm-17 [nucleoplasm] (Caenorhabditis elegans)

Rbm17 [nucleoplasm] (Mus musculus)

Rbm17 [nucleoplasm] (Rattus norvegicus)

rbm17 [nucleoplasm] (Xenopus tropicalis)

Ghost homologue of RBM17 [nucleoplasm] (Danio rerio)

Ghost homologue of RBM17 [nucleoplasm] (Schizosaccharomyces pombe)

RBM17 [nucleoplasm] (Bos taurus)

RBM17 [nucleoplasm] (Canis familiaris)

RBM17 [nucleoplasm] (Dictyostelium discoideum)

RBM17 [nucleoplasm] (Gallus gallus)

RBM17 [nucleoplasm] (Plasmodium falciparum)

RBM17 [nucleoplasm] (Sus scrofa)

Spf45 [nucleoplasm] (Drosophila melanogaster)

Cross References

RefSeq

NP_001139019.1, NP_116294.1

OpenTargets

ENSG00000134453

ENSEMBL

ENSP00000388638, ENST00000379888, ENSG00000134453, ENSP00000369218, ENST00000446108

HPA

ENSG00000134453-RBM17

GeneCards

RBM17

PRO

Q96I25

Pharos - Targets

Q96I25

GlyGen

Q96I25

PDB

6HIP, 5LSO, 2PEH, 2PE8

Interactors (17)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:O75533 SF3B1	1	SF3B1 [nucleoplasm] (R-HSA-71968)	0.912	10
UniProt:O43143 DHX15	1	DHX15 [nucleoplasm] (R-HSA-5688097)	0.882	12
UniProt:P21673 SAT1	1	SAT1 [cytosol] (R-HSA-351236)	0.87	13
UniProt:Q08379 GOLGA2	3	p-S37-GOLGA2 [Golgi membrane] (R-HSA-2172179) GOLGA2 [endoplasmic reticulum-Golgi intermediate compartment membrane] (R-HSA-2167933) GOLGA2 [Golgi membrane] (R-HSA-6808764)	0.83	8
UniProt:Q15637 SF1	1	SF1 [nucleoplasm] (R-HSA-8865928)	0.73	8
UniProt:Q15696 ZRSR2	1	ZRSR2 [nucleoplasm] (R-HSA-8865914)	0.643	4
UniProt:P52756 RBM5	1	RBM5 [nucleoplasm] (R-HSA-72049)	0.643	4
UniProt:P09661 SNRPA1	1	SNRPA1 [nucleoplasm] (R-HSA-71958)	0.643	3
UniProt:Q8IWZ8 SUGP1	1	SUGP1 [nucleoplasm] (R-HSA-72043)	0.632	3
UniProt:P16284 PECAM1	5	PECAM1 [plasma membrane] (R-HSA-114686) p-Y663,Y686-PECAM1(27-?) [plasma membrane] (R-HSA-210007) PECAM1 [secretory granule membrane] (R-HSA-6804778) p-Y713-PECAM1 [plasma membrane] (R-HSA-9860772) PECAM1 [platelet alpha granule membrane] (R-HSA-61489)	0.556	3
UniProt:P36957 DLST	5	Lipo-K110-DLST [mitochondrial matrix] (R-HSA-69993) SuccinyllipoH2-K110-DLST [mitochondrial matrix] (R-HSA-9853502) LipoH2-K110-DLST [mitochondrial matrix] (R-HSA-9853485) GlutaryllipoH2-K110-DLST [mitochondrial matrix] (R-HSA-9858581) DLST [mitochondrial matrix] (R-HSA-6792574)	0.556	3
UniProt:O76024 WFS1	3	WFS1 [endoplasmic reticulum lumen] (R-HSA-8956747) p-WFS1 [endoplasmic reticulum lumen] (R-HSA-8956998) WFS1 [endoplasmic reticulum membrane] (R-HSA-535474)	0.556	3
UniProt:P27797 CALR	6	CALR [lumenal side of endoplasmic reticulum membrane] (R-HSA-985502) CALR [endoplasmic reticulum lumen] (R-HSA-195905) CALR [extracellular region] (R-HSA-2197641) CALR [endocytic vesicle lumen] (R-HSA-2239448) CALR [endoplasmic reticulum-Golgi intermediate compartment membrane] (R-HSA-8863866) CALR [phagocytic vesicle membrane] (R-HSA-1236879)	0.556	3
UniProt:P62736 ACTA2	1	ACTA2 [cytosol] (R-HSA-445792)	0.527	2
UniProt:P62306 SNRPF	2	SNRPF [cytosol] (R-HSA-191852) SNRPF [nucleoplasm] (R-HSA-71907)	0.527	2
UniProt:Q8IX12 CCAR1	1	CCAR1 [nucleoplasm] (R-HSA-72048)	0.527	2
UniProt:Q9H9Z2 LIN28A	1	LIN28A [cytosol] (R-HSA-500391)	0.527	2

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