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RBM17 [nucleoplasm]
Stable Identifier
R-HSA-8865891
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
nucleoplasm
Synonyms
Splicing factor 45, SPF45_HUMAN
Locations in the PathwayBrowser
Expand all
Metabolism of RNA (Homo sapiens)
Processing of Capped Intron-Containing Pre-mRNA (Homo sapiens)
mRNA Splicing (Homo sapiens)
mRNA Splicing - Major Pathway (Homo sapiens)
Disassembly of the Intron Lariat Spliceosome (new) (Homo sapiens)
Intron Lariat Spliceosome (ILS) [nucleoplasm] (Homo sapiens)
U2 12S snRNP [nucleoplasm] (Homo sapiens)
RBM17 [nucleoplasm] (Homo sapiens)
U2 12S snRNP [nucleoplasm] (Homo sapiens)
RBM17 [nucleoplasm] (Homo sapiens)
Formation of the Spliceosomal A complex (Homo sapiens)
Spliceosomal A complex [nucleoplasm] (Homo sapiens)
U2 snRNP [nucleoplasm] (Homo sapiens)
RBM17 [nucleoplasm] (Homo sapiens)
U2 snRNP [nucleoplasm] (Homo sapiens)
RBM17 [nucleoplasm] (Homo sapiens)
Formation of the Spliceosomal B complex (Homo sapiens)
Spliceosomal B complex [nucleoplasm] (Homo sapiens)
U2 snRNP [nucleoplasm] (Homo sapiens)
RBM17 [nucleoplasm] (Homo sapiens)
Spliceosomal Pre-B complex [nucleoplasm] (Homo sapiens)
U2 snRNP [nucleoplasm] (Homo sapiens)
RBM17 [nucleoplasm] (Homo sapiens)
Formation of the Spliceosomal B* complex (Homo sapiens)
Spliceosomal B* complex [nucleoplasm] (Homo sapiens)
U2 12S snRNP [nucleoplasm] (Homo sapiens)
RBM17 [nucleoplasm] (Homo sapiens)
Spliceosomal Bact complex [nucleoplasm] (Homo sapiens)
U2 snRNP [nucleoplasm] (Homo sapiens)
RBM17 [nucleoplasm] (Homo sapiens)
Formation of the Spliceosomal Bact complex (Homo sapiens)
Spliceosomal B complex [nucleoplasm] (Homo sapiens)
U2 snRNP [nucleoplasm] (Homo sapiens)
RBM17 [nucleoplasm] (Homo sapiens)
Spliceosomal Bact complex [nucleoplasm] (Homo sapiens)
U2 snRNP [nucleoplasm] (Homo sapiens)
RBM17 [nucleoplasm] (Homo sapiens)
Formation of the Spliceosomal C* complex (Homo sapiens)
Spliceosomal C complex [nucleoplasm] (Homo sapiens)
U2 12S snRNP [nucleoplasm] (Homo sapiens)
RBM17 [nucleoplasm] (Homo sapiens)
Spliceosomal C* complex [nucleoplasm] (Homo sapiens)
U2 12S snRNP [nucleoplasm] (Homo sapiens)
RBM17 [nucleoplasm] (Homo sapiens)
Formation of the Spliceosomal P complex and exon ligation (Homo sapiens)
Spliceosomal C* complex [nucleoplasm] (Homo sapiens)
U2 12S snRNP [nucleoplasm] (Homo sapiens)
RBM17 [nucleoplasm] (Homo sapiens)
Spliceosomal P complex [nucleoplasm] (Homo sapiens)
U2 12S snRNP [nucleoplasm] (Homo sapiens)
RBM17 [nucleoplasm] (Homo sapiens)
Formation of the Spliceosomal Pre-B complex (Homo sapiens)
Spliceosomal A complex [nucleoplasm] (Homo sapiens)
U2 snRNP [nucleoplasm] (Homo sapiens)
RBM17 [nucleoplasm] (Homo sapiens)
Spliceosomal Pre-B complex [nucleoplasm] (Homo sapiens)
U2 snRNP [nucleoplasm] (Homo sapiens)
RBM17 [nucleoplasm] (Homo sapiens)
Spliceosomal P complex dissociates yielding the intron-containing complex (ILS) and the spliced mRNP (new) (Homo sapiens)
Intron Lariat Spliceosome (ILS) [nucleoplasm] (Homo sapiens)
U2 12S snRNP [nucleoplasm] (Homo sapiens)
RBM17 [nucleoplasm] (Homo sapiens)
Spliceosomal P complex [nucleoplasm] (Homo sapiens)
U2 12S snRNP [nucleoplasm] (Homo sapiens)
RBM17 [nucleoplasm] (Homo sapiens)
External Reference Information
External Reference
UniProt:Q96I25 RBM17
Gene Names
RBM17, SPF45
Chain
initiator methionine:, chain:2-401
Reference Genes
BioGPS Gene:84991 RBM17
COSMIC (genes):RBM17 RBM17
CTD Gene:84991 RBM17
dbSNP Gene:84991 RBM17
ENSEMBL:ENSG00000134453 RBM17
ENSEMBL_homo_sapiens_GENE:ENSG00000134453.16 RBM17
HGNC:16944 RBM17
KEGG Gene (Homo sapiens):84991 RBM17
Monarch:84991 RBM17
NCBI Gene:84991 RBM17
OMIM:606935 RBM17
UCSC:Q96I25 RBM17
Reference Transcript
RefSeq:NM_032905.4 RBM17
RefSeq:NM_001145547.1 RBM17
Other Identifiers
11721677_a_at
11721678_a_at
11721679_a_at
11733843_a_at
16702147
224780_PM_at
224780_at
224781_PM_s_at
224781_s_at
225751_PM_at
225751_at
3233548
3233549
3233550
3233551
3233552
3233553
3233558
3233559
3233560
3233561
3233564
3233567
3233570
3233573
3233577
3233579
3233581
3233582
3233583
3233584
3233585
3233586
3233587
3233588
3233589
3617985
3617990
3617991
49221_s_at
56356_at
7926021
84991
A_23_P35645
A_23_P35650
A_23_P423315
GE80333
GE86522
GO:0000380
GO:0000398
GO:0003676
GO:0003723
GO:0005515
GO:0005634
GO:0005654
GO:0005681
GO:0006397
GO:0008380
GO:0016071
GO:0032991
GO:0043226
GO:0045292
HMNXSV003034450
Hs.107001.0.S1_3p_a_at
Hs.107001.0.S2_3p_at
Hs.107001.1.S1_3p_at
ILMN_1781906
PH_hs_0005949
TC10000052.hg
Participates
as a component of
U2 snRNP [nucleoplasm] (Homo sapiens)
U2 12S snRNP [nucleoplasm] (Homo sapiens)
Inferred To
rbm-17 [nucleoplasm]
(Caenorhabditis elegans)
Rbm17 [nucleoplasm]
(Mus musculus)
Rbm17 [nucleoplasm]
(Rattus norvegicus)
rbm17 [nucleoplasm]
(Xenopus tropicalis)
Ghost homologue of RBM17 [nucleoplasm]
(Danio rerio)
Ghost homologue of RBM17 [nucleoplasm]
(Schizosaccharomyces pombe)
RBM17 [nucleoplasm]
(Bos taurus)
RBM17 [nucleoplasm]
(Canis familiaris)
RBM17 [nucleoplasm]
(Dictyostelium discoideum)
RBM17 [nucleoplasm]
(Gallus gallus)
RBM17 [nucleoplasm]
(Plasmodium falciparum)
RBM17 [nucleoplasm]
(Sus scrofa)
Spf45 [nucleoplasm]
(Drosophila melanogaster)
Cross References
RefSeq
NP_001139019.1
,
NP_116294.1
OpenTargets
ENSG00000134453
HPA
ENSG00000134453-RBM17
GeneCards
Q96I25
Ensembl
ENSP00000369218
,
ENSG00000134453
,
ENSP00000388638
,
ENST00000379888
,
ENST00000446108
PRO
Q96I25
Pharos - Targets
Q96I25
PDB
5LSO
,
2PEH
,
2PE8
,
6HIP
Interactors (16)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:O43143 DHX15
1
DHX15 [nucleoplasm]
(R-HSA-5688097)
0.882
12
UniProt:P21673 SAT1
1
SAT1 [cytosol]
(R-HSA-351236)
0.87
13
UniProt:O75533 SF3B1
1
SF3B1 [nucleoplasm]
(R-HSA-71968)
0.842
7
UniProt:Q08379 GOLGA2
3
p-S37-GOLGA2 [Golgi membrane]
(R-HSA-2172179)
GOLGA2 [endoplasmic reticulum-Golgi intermediate compartment membrane]
(R-HSA-2167933)
GOLGA2 [Golgi membrane]
(R-HSA-6808764)
0.83
8
UniProt:Q15637 SF1
1
SF1 [nucleoplasm]
(R-HSA-8865928)
0.73
8
UniProt:Q8IWZ8 SUGP1
1
SUGP1 [nucleoplasm]
(R-HSA-72043)
0.632
3
UniProt:O76024 WFS1
3
WFS1 [endoplasmic reticulum lumen]
(R-HSA-8956747)
p-WFS1 [endoplasmic reticulum lumen]
(R-HSA-8956998)
WFS1 [endoplasmic reticulum membrane]
(R-HSA-535474)
0.556
3
UniProt:P36957 DLST
5
Lipo-K110-DLST [mitochondrial matrix]
(R-HSA-69993)
SuccinyllipoH2-K110-DLST [mitochondrial matrix]
(R-HSA-9853502)
LipoH2-K110-DLST [mitochondrial matrix]
(R-HSA-9853485)
GlutaryllipoH2-K110-DLST [mitochondrial matrix]
(R-HSA-9858581)
DLST [mitochondrial matrix]
(R-HSA-6792574)
0.556
3
UniProt:P27797 CALR
6
CALR [lumenal side of endoplasmic reticulum membrane]
(R-HSA-985502)
CALR [extracellular region]
(R-HSA-2197641)
CALR [endocytic vesicle lumen]
(R-HSA-2239448)
CALR [endoplasmic reticulum lumen]
(R-HSA-195905)
CALR [endoplasmic reticulum-Golgi intermediate compartment membrane]
(R-HSA-8863866)
CALR [phagocytic vesicle membrane]
(R-HSA-1236879)
0.556
3
UniProt:P16284 PECAM1
5
PECAM1 [platelet alpha granule membrane]
(R-HSA-61489)
PECAM1 [plasma membrane]
(R-HSA-114686)
PECAM1 [secretory granule membrane]
(R-HSA-6804778)
p-Y663,Y686-PECAM1(27-?) [plasma membrane]
(R-HSA-210007)
p-Y713-PECAM1 [plasma membrane]
(R-HSA-9860772)
0.556
3
UniProt:P09661 SNRPA1
1
SNRPA1 [nucleoplasm]
(R-HSA-71958)
0.527
2
UniProt:P52756 RBM5
1
RBM5 [nucleoplasm]
(R-HSA-72049)
0.527
3
UniProt:Q15696 ZRSR2
1
ZRSR2 [nucleoplasm]
(R-HSA-8865914)
0.527
3
UniProt:P62736 ACTA2
1
ACTA2 [cytosol]
(R-HSA-445792)
0.527
2
UniProt:Q9H9Z2 LIN28A
1
LIN28A [cytosol]
(R-HSA-500391)
0.527
2
UniProt:P62306 SNRPF
2
SNRPF [nucleoplasm]
(R-HSA-71907)
SNRPF [cytosol]
(R-HSA-191852)
0.527
2
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