ZRSR2 [nucleoplasm]

Stable Identifier
R-HSA-8865914
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
Synonyms
U2 small nuclear ribonucleoprotein auxiliary factor 35 kDa subunit-related protein 2, U2AFM_HUMAN
Locations in the PathwayBrowser for interactor UniProt:Q9Y2D8 ADIP
Literature References
PubMed ID Title Journal Year
21041408 The U2AF35-related protein Urp contacts the 3' splice site to promote U12-type intron splicing and the second step of U2-type intron splicing

Zheng, X, Shen, H, Luecke, S, Green, MR

Genes Dev. 2010
25586593 Aberrant splicing of U12-type introns is the hallmark of ZRSR2 mutant myelodysplastic syndrome

Kohlmann, A, Miyano, S, Grossmann, V, Sundaresan, J, Ganser, A, Thol, F, Li, J, Yang, H, Madan, V, Haferlach, T, Shiraishi, Y, Ogawa, S, Sanada, M, Sato-Otsubo, A, Koeffler, HP, Okamoto, R, Kanojia, D

Nat Commun 2015
External Reference Information
External Reference
Gene Names
ZRSR2, U2AF1-RS2, U2AF1L2, U2AF1RS2, URP
Chain
chain:1-482
Reference Transcript
Other Identifiers
11758542_x_at
208174_3p_x_at
208174_PM_x_at
208174_x_at
213876_3p_x_at
213876_PM_x_at
213876_x_at
2824319
2824320
2824321
2824322
2824324
35060_at
38523_f_at
3969948
3969950
3969953
3969956
3969957
3969960
3969963
3969968
3969969
3969970
3969971
3969973
3969974
3969975
3969976
8166195
8233
D49677_at
GE57231
GO:0000245
GO:0000398
GO:0003676
GO:0003723
GO:0005515
GO:0005634
GO:0005654
GO:0005681
GO:0005689
GO:0006397
GO:0008380
GO:0016071
GO:0030628
GO:0042802
GO:0043226
GO:0046872
GO:0065003
GO:0089701
GO:1990904
HMNXSV003034635
Hs.171909.1.S1_3p_a_at
ILMN_1773868
TC0X000072.hg
g13186299_3p_s_at
g4827045_3p_a_at
Participates
Inferred To
Cross References
RefSeq
OpenTargets
GeneCards
PRO
Pharos - Targets
Orphanet
Interactors (40)
Accession #Entities Entities Confidence Score Evidence (IntAct)
 UniProt:P78362 SRPK2  1 0.837 8
 UniProt:Q9H190 SDCB2      0.781 7
 UniProt:Q15695 U2AFL      0.742 6
 UniProt:P49760 CLK2      0.718 8
 UniProt:Q96SB4 SRPK1  2 0.688 3
 UniProt:Q9Y2D8 ADIP      0.666 4
 UniProt:P62306 SNRPF  2 0.643 3
 UniProt:O75533 SF3B1  1 0.643 5
 UniProt:Q13243 SRSF5  1 0.556 3
 UniProt:Q92997 DVL3  4 0.556 3
 UniProt:Q6BDI9 REP15      0.556 3
 UniProt:Q96N21 AP4AT      0.556 3
 UniProt:Q7Z7F0-4 KHDC4      0.556 3
 UniProt:Q9UK58 CCNL1      0.556 3
 UniProt:Q9Y383 LC7L2      0.556 3
 UniProt:Q15696 ZRSR2  1 0.556 3
 UniProt:A7MD48 SRRM4      0.556 3
 UniProt:Q8WVP5 TNFAIP8L1  1 0.556 3
 UniProt:P62304 SNRPE  2 0.527 3
 UniProt:Q6IEG0 SNRNP48  1 0.527 4
 UniProt:Q9BWU0 NADAP      0.527 2
 UniProt:Q96LT9 RNPC3  1 0.527 4
 UniProt:P30414 NKTR      0.527 2
 UniProt:Q9UDW3 ZMAT5  1 0.527 2
 UniProt:P52756 RBM5  1 0.527 2
 UniProt:Q07021 C1QBP  3 0.527 3
 UniProt:P50452 SERPINB8  1 0.527 2
 UniProt:Q96F63 CCD97      0.527 2
 UniProt:Q13435 SF3B2  1 0.527 4
 UniProt:Q6PID6 TTC33      0.527 2
 UniProt:Q8N954 GPT11      0.527 2
 UniProt:Q15459 SF3A1  1 0.527 2
 UniProt:Q8IWX8 CHERP  1 0.527 3
 UniProt:P14678 SNRPB  4 0.527 2
 UniProt:Q8N8D1 PDCD7  1 0.527 4
 UniProt:Q8TBF4 ZCRB1  2 0.527 3
 UniProt:P42357 HAL  1 0.527 2
 UniProt:Q12874 SF3A3  1 0.527 2
 UniProt:P63162 SNRPN  1 0.527 2
 UniProt:Q96I25 RBM17  1 0.527 3
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