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U2SURP [nucleoplasm]
Stable Identifier
R-HSA-8865950
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
nucleoplasm
Synonyms
U2 snRNP-associated SURP motif-containing protein, SR140_HUMAN
Locations in the PathwayBrowser
Expand all
Metabolism of RNA (Homo sapiens)
Processing of Capped Intron-Containing Pre-mRNA (Homo sapiens)
mRNA Splicing (Homo sapiens)
mRNA Splicing - Major Pathway (Homo sapiens)
Disassembly of the Intron Lariat Spliceosome (new) (Homo sapiens)
Intron Lariat Spliceosome (ILS) [nucleoplasm] (Homo sapiens)
U2 12S snRNP [nucleoplasm] (Homo sapiens)
U2SURP [nucleoplasm] (Homo sapiens)
U2 12S snRNP [nucleoplasm] (Homo sapiens)
U2SURP [nucleoplasm] (Homo sapiens)
Formation of the Spliceosomal A complex (Homo sapiens)
Spliceosomal A complex [nucleoplasm] (Homo sapiens)
U2 snRNP [nucleoplasm] (Homo sapiens)
U2SURP [nucleoplasm] (Homo sapiens)
U2 snRNP [nucleoplasm] (Homo sapiens)
U2SURP [nucleoplasm] (Homo sapiens)
Formation of the Spliceosomal B complex (Homo sapiens)
Spliceosomal B complex [nucleoplasm] (Homo sapiens)
U2 snRNP [nucleoplasm] (Homo sapiens)
U2SURP [nucleoplasm] (Homo sapiens)
Spliceosomal Pre-B complex [nucleoplasm] (Homo sapiens)
U2 snRNP [nucleoplasm] (Homo sapiens)
U2SURP [nucleoplasm] (Homo sapiens)
Formation of the Spliceosomal B* complex (Homo sapiens)
Spliceosomal B* complex [nucleoplasm] (Homo sapiens)
U2 12S snRNP [nucleoplasm] (Homo sapiens)
U2SURP [nucleoplasm] (Homo sapiens)
Spliceosomal Bact complex [nucleoplasm] (Homo sapiens)
U2 snRNP [nucleoplasm] (Homo sapiens)
U2SURP [nucleoplasm] (Homo sapiens)
Formation of the Spliceosomal Bact complex (Homo sapiens)
Spliceosomal B complex [nucleoplasm] (Homo sapiens)
U2 snRNP [nucleoplasm] (Homo sapiens)
U2SURP [nucleoplasm] (Homo sapiens)
Spliceosomal Bact complex [nucleoplasm] (Homo sapiens)
U2 snRNP [nucleoplasm] (Homo sapiens)
U2SURP [nucleoplasm] (Homo sapiens)
Formation of the Spliceosomal C* complex (Homo sapiens)
Spliceosomal C complex [nucleoplasm] (Homo sapiens)
U2 12S snRNP [nucleoplasm] (Homo sapiens)
U2SURP [nucleoplasm] (Homo sapiens)
Spliceosomal C* complex [nucleoplasm] (Homo sapiens)
U2 12S snRNP [nucleoplasm] (Homo sapiens)
U2SURP [nucleoplasm] (Homo sapiens)
Formation of the Spliceosomal P complex and exon ligation (Homo sapiens)
Spliceosomal C* complex [nucleoplasm] (Homo sapiens)
U2 12S snRNP [nucleoplasm] (Homo sapiens)
U2SURP [nucleoplasm] (Homo sapiens)
Spliceosomal P complex [nucleoplasm] (Homo sapiens)
U2 12S snRNP [nucleoplasm] (Homo sapiens)
U2SURP [nucleoplasm] (Homo sapiens)
Formation of the Spliceosomal Pre-B complex (Homo sapiens)
Spliceosomal A complex [nucleoplasm] (Homo sapiens)
U2 snRNP [nucleoplasm] (Homo sapiens)
U2SURP [nucleoplasm] (Homo sapiens)
Spliceosomal Pre-B complex [nucleoplasm] (Homo sapiens)
U2 snRNP [nucleoplasm] (Homo sapiens)
U2SURP [nucleoplasm] (Homo sapiens)
Spliceosomal P complex dissociates yielding the intron-containing complex (ILS) and the spliced mRNP (new) (Homo sapiens)
Intron Lariat Spliceosome (ILS) [nucleoplasm] (Homo sapiens)
U2 12S snRNP [nucleoplasm] (Homo sapiens)
U2SURP [nucleoplasm] (Homo sapiens)
Spliceosomal P complex [nucleoplasm] (Homo sapiens)
U2 12S snRNP [nucleoplasm] (Homo sapiens)
U2SURP [nucleoplasm] (Homo sapiens)
External Reference Information
External Reference
UniProt:O15042 U2SURP
Gene Names
U2SURP, KIAA0332, SR140
Chain
initiator methionine:, chain:2-1029
Reference Genes
BioGPS Gene:23350 U2SURP
COSMIC (genes):U2SURP U2SURP
CTD Gene:23350 U2SURP
dbSNP Gene:23350 U2SURP
ENSEMBL:ENSG00000163714 U2SURP
ENSEMBL_homo_sapiens_GENE:ENSG00000163714.18 U2SURP
HGNC:30855 U2SURP
KEGG Gene (Homo sapiens):23350 U2SURP
Monarch:23350 U2SURP
NCBI Gene:23350 U2SURP
OMIM:617849 U2SURP
UCSC:O15042 U2SURP
Reference Transcript
RefSeq:XM_017006038.1 U2SURP
RefSeq:NM_001320220.1 U2SURP
RefSeq:NM_001080415.1 U2SURP
RefSeq:XM_017006039.1 U2SURP
RefSeq:NM_001320222.1 U2SURP
RefSeq:NM_001320219.1 U2SURP
Other Identifiers
11743562_a_at
11747164_a_at
11747485_a_at
16946553
212058_3p_at
212058_PM_at
212058_at
212060_PM_at
212060_at
212061_PM_at
212061_at
23350
2629674
2629678
2646051
2646052
2646054
2646055
2646056
2646058
2646059
2646061
2646062
2646063
2646064
2646065
2646066
2646068
2646074
2646075
2646076
2646078
2646079
2646080
2646081
2646083
2646084
2646085
2646086
2646090
2646095
2646098
2646099
2646102
2646103
2646104
2646105
2646106
2646107
2646108
2646109
2646110
38030_at
52605_at
8083183
A_24_P323932
GE53061
GO:0003676
GO:0003723
GO:0005515
GO:0005634
GO:0005654
GO:0006396
GO:0043226
HMNXSV003006296
Hs.7976.0.A1_3p_at
Hs.7976.0.A1_3p_s_at
Hs.7976.0.A2_3p_at
Hs.7976.0.A3_3p_at
ILMN_2286334
PH_hs_0024164
TC03000774.hg
Participates
as a component of
U2 snRNP [nucleoplasm] (Homo sapiens)
U2 12S snRNP [nucleoplasm] (Homo sapiens)
Inferred To
u2surp [nucleoplasm]
(Xenopus tropicalis)
Ghost homologue of U2SURP [nucleoplasm]
(Bos taurus)
sap-140 [nucleoplasm]
(Caenorhabditis elegans)
U2SURP [nucleoplasm]
(Canis familiaris)
U2SURP [nucleoplasm]
(Danio rerio)
U2SURP [nucleoplasm]
(Dictyostelium discoideum)
U2SURP [nucleoplasm]
(Gallus gallus)
U2SURP [nucleoplasm]
(Plasmodium falciparum)
U2SURP [nucleoplasm]
(Schizosaccharomyces pombe)
U2SURP [nucleoplasm]
(Sus scrofa)
cg9346 [nucleoplasm]
(Drosophila melanogaster)
U2surp [nucleoplasm]
(Mus musculus)
U2surp [nucleoplasm]
(Rattus norvegicus)
Cross References
RefSeq
NP_001307148.1
,
NP_001073884.1
,
XP_016861528.1
,
XP_016861527.1
,
NP_001307151.1
,
NP_001307149.1
OpenTargets
ENSG00000163714
HPA
ENSG00000163714-U2SURP
GeneCards
O15042
Ensembl
ENST00000473835
,
ENSP00000418563
,
ENSG00000163714
PRO
O15042
Pharos - Targets
O15042
Interactors (3)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:Q9H9Z2 LIN28A
1
LIN28A [cytosol]
(R-HSA-500391)
0.527
3
UniProt:P09661 SNRPA1
1
SNRPA1 [nucleoplasm]
(R-HSA-71958)
0.527
2
UniProt:P52756 RBM5
1
RBM5 [nucleoplasm]
(R-HSA-72049)
0.508
2
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