Reactome | GYPA [plasma membrane]

GYPA [plasma membrane]

Stable Identifier

R-HSA-8867204

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

plasma membrane

Synonyms

Glycophorin-A, GLPA_HUMAN

Locations in the PathwayBrowser

Expand all

External Reference Information

External Reference

UniProt:P02724 GYPA

Gene Names

GYPA, GPA

Chain

signal peptide:1-19, chain:20-150

Reference Genes

BioGPS Gene:2993 GYPA

COSMIC (genes):GYPA GYPA

CTD Gene:2993 GYPA

dbSNP Gene:2993 GYPA

ENSEMBL:ENSG00000170180 GYPA

HGNC:4702 GYPA

KEGG:hsa:2993 GYPA

Monarch:2993 GYPA

NCBI Gene:2993 GYPA

OMIM:617922 GYPA

UCSC:P02724 GYPA

Reference Transcript

Other Identifiers

11732235_a_at

11732236_a_at

11732237_a_at

11745661_x_at

11751870_x_at

16980267

205837_PM_s_at

205837_s_at

205838_PM_at

205838_at

211820_PM_x_at

211820_x_at

211821_PM_x_at

211821_x_at

2787923

2787966

2787972

2787981

2787982

2788004

2788005

2788006

2788007

2788008

2788011

2788012

2788014

2788015

2788016

2788017

2788018

2788021

2788031

2788034

2788035

2993

38714_at

8102998

A_23_P45180

A_24_P12059

A_33_P3362915

A_33_P3362933

GE79929

GO:0001618

GO:0003674

GO:0005515

GO:0005575

GO:0005654

GO:0005829

GO:0005886

GO:0008150

GO:0016020

GO:0042802

GO:0046718

GO:0170014

HMNXSV003013048

HMNXSV003040374

Hs2.344709.1.S1_3p_at

ILMN_1799708

L31860_at

M71243_f_at

PH_hs_0039962

S77893_s_at

TC04002764.hg

TC04002927.hg

g13529076_3p_a_at

g392430_3p_a_at

g8051602_3p_at

Participates

as a member of

GYPA,GYPB,GYPC [plasma membrane] (Homo sapiens)

Cross References

OpenTargets

ENSG00000170180

ENSEMBL

ENST00000642713, ENSP00000324483, ENSP00000495922, ENSP00000494092, ENST00000324022, ENST00000646447

HPA

ENSG00000170180-GYPA

ZINC - Substances

GLPA_HUMAN

ZINC target

P02724

PRO

P02724

Pharos - Targets

P02724

GlyGen

P02724

PDB

8CTE, 7UZ3, 5EH4, 5EH6, 8CT3, 8CRQ, 7V19, 8CS9, 7V07, 8CRR, 8CSL, 1AFO, 7V0K, 2KPF, 8CRT, 2KPE

HMDB Protein

HMDBP14357

Interactors (9)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:Q14145 KEAP1	3	KEAP1 [cytosol] (R-HSA-976038) ub-KEAP1 [cytosol] (R-HSA-9766647) Ub-KEAP1 [cytosol] (R-HSA-6782766)	0.666	4
UniProt:Q13651 IL10RA	3	p-Y446-IL10RA [plasma membrane] (R-HSA-6784810) p-Y496-IL10RA [plasma membrane] (R-HSA-6784793) IL10RA [plasma membrane] (R-HSA-449841)	0.556	3
UniProt:Q15125 EBP	1	EBP [endoplasmic reticulum membrane] (R-HSA-195697)	0.556	3
UniProt:O15552 FFAR2	1	FFAR2 [plasma membrane] (R-HSA-443944)	0.556	3
UniProt:Q3KNW5 SLC10A6	1	SLC10A6 [plasma membrane] (R-HSA-433091)	0.556	3
UniProt:O00501 CLDN5	2	CLDN5 [cell junction] (R-HSA-421264) CLDN5 [plasma membrane] (R-HSA-419991)	0.556	3
UniProt:Q13535 ATR	1	ATR [nucleoplasm] (R-HSA-912443)	0.527	2
UniProt:P52630 STAT2	4	p-Y690-STAT2 [cytosol] (R-HSA-909683) STAT2 [cytosol] (R-HSA-882029) p-Y690-STAT2 [nucleoplasm] (R-HSA-909673) p-Y-STAT2 [cytosol] (R-HSA-8987235)	0.527	2
UniProt:Q96BI1 SLC22A18	3	SLC22A18 R286H [plasma membrane] (R-HSA-5625583) SLC22A18 S233F [plasma membrane] (R-HSA-5625564) SLC22A18 [plasma membrane] (R-HSA-561110)	0.527	2