Reactome | F- and N- BAR domain proteins bind the clathrin-coated pit

F- and N- BAR domain proteins bind the clathrin-coated pit

Stable Identifier

R-HSA-8867754

Type

Reaction [binding]

Species

Homo sapiens

Compartment

plasma membrane

ReviewStatus

5/5

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F- and N- BAR domain proteins bind the clathrin-coated pit

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BAR (BIN/amphiphysin/Rvs) domain proteins sense and contribute to membrane curvature. BAR domain proteins generally form long, coiled-coil homo- or hetero-dimers with a concave inner surface that interacts with membranes (reviewed in Gallop and McMahon, 2005; Daumke et al, 2014). F-BAR domain proteins such as FCHo 1 and 2 recognize shallow membrane curvature and are generally recruited early in the formation of clathrin-coated pit (Itoh et al, 2005; Kamioka et al, 2004; Henne et al, 2007; Shimada et al, 2007; Henne et al, 2010). FNBP proteins and N-BAR containing endocytic proteins such as SNX9 and 18, amphiphysin (AMPH) and endophilins recognize regions of membrane with greater curvature, interact with dynamin and likely play a later role in CCP formation with spatiotemporal coupling to vesicle scission (Kamioka et al, 2004; Itoh et al, 2005; Soulet et al, 2005; Shimada et al, 2007; Shin et al, 2008; Taylor et al, 2011; reveiwed in McMahon and Boucrot, 2011). These proteins are recruited to the complex through interactions with core components of the clathrin-coated pit, and in the case of SNX9, also through interaction with PI(3,4)P2, which is generated at late stages by clathrin-associated PIK3C2A (Lundmark and Carlson, 2003; Schmid et al, 2006; Dergai et al, 2010; Brett et al, 2002 : Posor et al, 2013; reviewed in Daumke et al, 2014). Early BAR domain containing proteins such as FCHo1 and 2 are not present in either late stage clathrin-coated pits or in free clathrin-coated vesicles. Although the precise timing of their dissociation is not known, in this pathway, they are shown leaving the clathrin-coated pit upon recruitment of the more highly curved N-BAR proteins (Taylor et al, 2011).

Literature References

PubMed ID	Title	Journal	Year
17512409	Curved EFC/F-BAR-domain dimers are joined end to end into a filament for membrane invagination in endocytosis Shimada, A, Niwa, H, Tsujita, K, Suetsugu, S, Nitta, K, Hanawa-Suetsugu, K, Akasaka, R, Nishino, Y, Toyama, M, Chen, L, Liu, ZJ, Wang, BC, Yamamoto, M, Terada, T, Miyazawa, A, Tanaka, A, Sugano, S, Shirouzu, M, Nagayama, K, Takenawa, T, Yokoyama, S	Cell	2007
17540576	Structure and analysis of FCHo2 F-BAR domain: a dimerizing and membrane recruitment module that effects membrane curvature Henne, WM, Kent, HM, Ford, MG, Hegde, BG, Daumke, O, Butler, PJ, Mittal, R, Langen, R, Evans, PR, McMahon, HT	Structure	2007
21779028	Molecular mechanism and physiological functions of clathrin-mediated endocytosis McMahon, HT, Boucrot, E	Nat. Rev. Mol. Cell Biol.	2011
15703209	SNX9 regulates dynamin assembly and is required for efficient clathrin-mediated endocytosis Soulet, F, Yarar, D, Leonard, M, Schmid, SL	Mol. Biol. Cell	2005
23823722	Spatiotemporal control of endocytosis by phosphatidylinositol-3,4-bisphosphate Posor, Y, Eichhorn-Gruenig, M, Puchkov, D, Schöneberg, J, Ullrich, A, Lampe, A, Müller, R, Zarbakhsh, S, Gulluni, F, Hirsch, E, Krauss, M, Schultz, C, Schmoranzer, J, Noé, F, Haucke, V	Nature	2013
16903783	Role of the AP2 beta-appendage hub in recruiting partners for clathrin-coated vesicle assembly Schmid, EM, Ford, MG, Burtey, A, Praefcke, GJ, Peak-Chew, SY, Mills, IG, Benmerah, A, McMahon, HT	PLoS Biol.	2006
20448150	FCHo proteins are nucleators of clathrin-mediated endocytosis Henne, WM, Boucrot, E, Meinecke, M, Evergren, E, Vallis, Y, Mittal, R, McMahon, HT	Science	2010
16326391	Dynamin and the actin cytoskeleton cooperatively regulate plasma membrane invagination by BAR and F-BAR proteins Itoh, T, Erdmann, KS, Roux, A, Habermann, B, Werner, H, De Camilli, P	Dev. Cell	2005
12057195	Accessory protein recruitment motifs in clathrin-mediated endocytosis Brett, TJ, Traub, LM, Fremont, DH	Structure	2002
15649145	BAR domains and membrane curvature: bringing your curves to the BAR Gallop, JL, McMahon, HT	Biochem. Soc. Symp.	2005
12952949	Sorting nexin 9 participates in clathrin-mediated endocytosis through interactions with the core components Lundmark, R, Carlsson, SR	J. Biol. Chem.	2003
20946875	Intersectin 1 forms complexes with SGIP1 and Reps1 in clathrin-coated pits Dergai, O, Novokhatska, O, Dergai, M, Skrypkina, I, Tsyba, L, Moreau, J, Rynditch, A	Biochem. Biophys. Res. Commun.	2010
24581490	BAR domain scaffolds in dynamin-mediated membrane fission Daumke, O, Roux, A, Haucke, V	Cell	2014
21445324	A high precision survey of the molecular dynamics of mammalian clathrin-mediated endocytosis Taylor, MJ, Perrais, D, Merrifield, CJ	PLoS Biol.	2011
15252009	A novel dynamin-associating molecule, formin-binding protein 17, induces tubular membrane invaginations and participates in endocytosis Kamioka, Y, Fukuhara, S, Sawa, H, Nagashima, K, Masuda, M, Matsuda, M, Mochizuki, N	J. Biol. Chem.	2004
18388313	SNX9 regulates tubular invagination of the plasma membrane through interaction with actin cytoskeleton and dynamin 2 Shin, N, Ahn, N, Chang-Ileto, B, Park, J, Takei, K, Ahn, SG, Kim, SA, Di Paolo, G, Chang, S	J. Cell. Sci.	2008