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OSBPL8 [cytosol]
Stable Identifier
R-HSA-8867870
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
cytosol
Synonyms
Oxysterol-binding protein-related protein 8, OSBL8_HUMAN
Locations in the PathwayBrowser
Expand all
Metabolism (Homo sapiens)
Metabolism of lipids (Homo sapiens)
Phospholipid metabolism (Homo sapiens)
Glycerophospholipid biosynthesis (Homo sapiens)
Acyl chain remodelling of PS (Homo sapiens)
OSBPL5,8,10 exchange PS with PI4P from ER membrane to plasma membrane (Homo sapiens)
OSBPL5,8,10 [cytosol] (Homo sapiens)
OSBPL8 [cytosol] (Homo sapiens)
External Reference Information
External Reference
UniProt:Q9BZF1 OSBPL8
Gene Names
OSBPL8, KIAA1451, ORP8, OSBP10
Chain
chain:1-889
Reference Genes
BioGPS Gene:114882 OSBPL8
COSMIC (genes):OSBPL8 OSBPL8
CTD Gene:114882 OSBPL8
dbSNP Gene:114882 OSBPL8
ENSEMBL:ENSG00000091039 OSBPL8
ENSEMBL_homo_sapiens_GENE:ENSG00000091039.17 OSBPL8
HGNC:16396 OSBPL8
KEGG Gene (Homo sapiens):114882 OSBPL8
Monarch:114882 OSBPL8
NCBI Gene:114882 OSBPL8
OMIM:606736 OSBPL8
UCSC:Q9BZF1 OSBPL8
Reference Transcript
RefSeq:XM_005268621.4 OSBPL8
RefSeq:NM_001319655.1 OSBPL8
RefSeq:XM_006719224.2 OSBPL8
RefSeq:NM_001003712.1 OSBPL8
RefSeq:NM_020841.4 OSBPL8
RefSeq:NM_001319652.1 OSBPL8
Other Identifiers
114882
11718642_s_at
11718643_a_at
11718644_x_at
11718645_a_at
11718646_s_at
11755548_a_at
16767788
16767794
212582_PM_at
212582_at
212585_PM_at
212585_at
228986_PM_at
228986_at
3462942
3462943
3462944
3462945
3462946
3462948
3462950
3462951
3462952
3462953
3462954
3462955
3462958
3462959
3462960
3462962
3462966
3462969
3462970
3462971
3462974
3462976
3462977
3462978
3462979
3462982
3462983
3462984
3462985
3462986
3462988
3462990
3462998
3462999
3463000
3463005
3463006
3463016
3463017
3463018
3463019
3463020
3463022
41438_at
50409_at
7965064
80340_at
A_23_P204810
A_24_P153511
A_33_P3254191
GE56201
GO:0001786
GO:0005215
GO:0005515
GO:0005548
GO:0005634
GO:0005635
GO:0005783
GO:0005789
GO:0005829
GO:0006575
GO:0006629
GO:0006869
GO:0008289
GO:0010891
GO:0015248
GO:0015485
GO:0015914
GO:0015918
GO:0016020
GO:0023052
GO:0030154
GO:0030336
GO:0031965
GO:0032541
GO:0036150
GO:0043226
GO:0043231
GO:0045444
GO:0046326
GO:0046628
GO:0048870
GO:0051897
GO:0055085
GO:0061024
GO:0070273
GO:0090204
GO:0120009
GO:0140343
HMNXSV003002452
Hs.109694.0.A1_3p_at
Hs.109694.0.A2_3p_at
Hs.321129.0.S1_3p_s_at
ILMN_1782459
ILMN_2405078
PH_hs_0031521
TC12001754.hg
Participates
as a member of
OSBPL5,8,10 [cytosol] (Homo sapiens)
Inferred To
OSBPL8 [cytosol]
(Bos taurus)
OSBPL8 [cytosol]
(Canis familiaris)
OSBPL8 [cytosol]
(Gallus gallus)
OSBPL8 [cytosol]
(Mus musculus)
OSBPL8 [cytosol]
(Saccharomyces cerevisiae)
OSBPL8 [cytosol]
(Schizosaccharomyces pombe)
OSBPL8 [cytosol]
(Sus scrofa)
osbG [cytosol]
(Dictyostelium discoideum)
Osbpl8 [cytosol]
(Rattus norvegicus)
Homologues of OSBPL8 [cytosol]
(Dictyostelium discoideum)
Homologues of OSBPL8 [cytosol]
(Saccharomyces cerevisiae)
obr-3 [cytosol]
(Caenorhabditis elegans)
osbJ [cytosol]
(Dictyostelium discoideum)
osbD [cytosol]
(Dictyostelium discoideum)
osbC [cytosol]
(Dictyostelium discoideum)
Orp8 [cytosol]
(Drosophila melanogaster)
osbB [cytosol]
(Dictyostelium discoideum)
osbE [cytosol]
(Dictyostelium discoideum)
osbA [cytosol]
(Dictyostelium discoideum)
osbL [cytosol]
(Dictyostelium discoideum)
Cross References
RefSeq
XP_006719287.1
,
NP_001003712.1
,
NP_001306584.1
,
NP_065892.1
,
NP_001306581.1
,
XP_005268678.1
OpenTargets
ENSG00000091039
GeneCards
Q9BZF1
HPA
ENSG00000091039-OSBPL8
Ensembl
ENST00000393249
,
ENSP00000261183
,
ENST00000393250
,
ENST00000261183
,
ENSP00000478240
,
ENSP00000376939
,
ENSP00000376940
,
ENST00000611266
,
ENSG00000091039
PRO
Q9BZF1
Pharos - Targets
Q9BZF1
PDB
1V88
,
8P7A
,
5U78
,
5U77
Interactors (1)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:O15530 PDPK1
3
p-S241-PDPK1 [cytosol]
(R-HSA-9860799)
PDPK1 [cytosol]
(R-HSA-202210)
PDPK1 [plasma membrane]
(R-HSA-61459)
0.527
2
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