Reactome | PPIL1 [nucleoplasm]

PPIL1 [nucleoplasm]

Stable Identifier

R-HSA-8867892

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

nucleoplasm

Synonyms

Peptidyl-prolyl cis-trans isomerase-like 1, PPIL1_HUMAN

Locations in the PathwayBrowser

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External Reference Information

External Reference

UniProt:Q9Y3C6 PPIL1

Gene Names

PPIL1, CYPL1, CGI-124, UNQ2425/PRO4984

Chain

chain:1-166

Reference Genes

BioGPS Gene:51645 PPIL1

COSMIC (genes):PPIL1 PPIL1

CTD Gene:51645 PPIL1

dbSNP Gene:51645 PPIL1

ENSEMBL:ENSG00000137168 PPIL1

HGNC:9260 PPIL1

KEGG:hsa:51645 PPIL1

Monarch:51645 PPIL1

NCBI Gene:51645 PPIL1

OMIM:601301 PPIL1

UCSC:Q9Y3C6 PPIL1

Reference Transcript

RefSeq:NM_016059.4 PPIL1

Other Identifiers

11718035_at

11718036_at

11757669_s_at

17018685

222500_PM_at

222500_at

2952066

2952067

2952068

2952070

2952071

2952072

2952073

51169_at

51645

75054_at

8126058

A_23_P133995

GE58666

GO:0000398

GO:0000413

GO:0003755

GO:0003824

GO:0005515

GO:0005634

GO:0005654

GO:0005681

GO:0006397

GO:0006457

GO:0008380

GO:0016018

GO:0016071

GO:0016853

GO:0043226

GO:0048856

GO:0071007

GO:0071013

GO:0097718

GO:0140096

GO:1990403

HMNXSV003026461

ILMN_2054392

TC06001679.hg

g12804374_3p_at

Participates

as an output of

Disassembly of the Intron Lariat Spliceosome (new) (Homo sapiens)

as an input of

Formation of the Spliceosomal Bact complex (Homo sapiens)

as a component of

as a member of

PPIL [nucleoplasm] (Homo sapiens)

Inferred To

cypE [nucleoplasm] (Dictyostelium discoideum)

ppi1 [nucleoplasm] (Schizosaccharomyces pombe)

PPIL1 [nucleoplasm] (Bos taurus)

PPIL1 [nucleoplasm] (Canis familiaris)

PPIL1 [nucleoplasm] (Danio rerio)

PPIL1 [nucleoplasm] (Gallus gallus)

PPIL1 [nucleoplasm] (Mus musculus)

PPIL1 [nucleoplasm] (Plasmodium falciparum)

PPIL1 [nucleoplasm] (Rattus norvegicus)

PPIL1 [nucleoplasm] (Sus scrofa)

PPIL1 [nucleoplasm] (Xenopus tropicalis)

Cypl [nucleoplasm] (Drosophila melanogaster)

cyn-12 [nucleoplasm] (Caenorhabditis elegans)

Cross References

RefSeq

NP_057143.1

OpenTargets

ENSG00000137168

ENSEMBL

ENSP00000362803, ENST00000373699

HPA

ENSG00000137168-PPIL1

PRO

Q9Y3C6

Pharos - Targets

Q9Y3C6

GlyGen

Q9Y3C6

HMDB Protein

HMDBP12808

PDB

1XWN, 6ICZ, 6ID1, 6FF7, 2X7K, 8CH6, 7W5B, 7W5A, 6ZYM, 5MQF, 2K7N, 5Z57, 7QTT, 6QDV, 5YZG, 5Z56, 7W59, 6ID0, 6FF4, 8C6J, 5XJC

Interactors (19)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:Q13573 SNW1	1	SNW1 [nucleoplasm] (R-HSA-351663)	0.926	17
UniProt:Q16630 CPSF6	2	CPSF6(1-490)-FGFR1(429-822) fusion [cytosol] (R-HSA-1614368) CPSF6(1-490)-p-FGFR1(429-822) fusion [cytosol] (R-HSA-1838987)	0.666	4
UniProt:Q9BRX9 WDR83	1	WDR83 [endosome membrane] (R-HSA-5672942)	0.632	3
UniProt:Q9CSN1 Snw1	1	Snw1 [nucleoplasm] (R-MMU-2065315)	0.564	2
UniProt:P50458 LHX2	1	LHX2 [nucleoplasm] (R-HSA-9011100)	0.556	3
UniProt:P0CG20 PRR35			0.556	3
UniProt:Q92802 N42L2			0.556	3
UniProt:P78424 PO6F2			0.556	3
UniProt:P15884-3 TCF4			0.556	3
IntAct:EBI-10220116 163154			0.556	3
UniProt:Q96D03 DDT4L			0.556	3
UniProt:A6NLX3 SPDE4			0.556	3
UniProt:Q5T749 KPRP	1	KPRP [cytosol] (R-HSA-9839614)	0.556	3
UniProt:Q9UFD9 RIM3A			0.556	3
UniProt:P15884 TCF4	1	TCF4 [nucleoplasm] (R-HSA-445672)	0.556	3
UniProt:Q9UMD9 COL17A1	20	GlcGalHyl-COL17A1(1-1497) [endoplasmic reticulum lumen] (R-HSA-2173102) GalHyl-COL17A1(1-1497) [endoplasmic reticulum lumen] (R-HSA-2173084) 3x4Hyp-GlcGalHyl-COL17A1(1-1497) [endoplasmic reticulum lumen] (R-HSA-2173190) 3x4Hyp-3Hyp-GalHyl-COL17A1(1-1497) [endoplasmic reticulum lumen] (R-HSA-2173237) 3x4Hyp-GalHyl-COL17A1(1-1497) [endoplasmic reticulum lumen] (R-HSA-2173184) 3x4Hyp-3Hyp-GlcGalHyl-COL17A1(1-1497) [endoplasmic reticulum lumen] (R-HSA-2173264) 3x4Hyp-COL17A1(1-1497) [endoplasmic reticulum lumen] (R-HSA-2172934) 3x4Hyp-3Hyp-COL17A1(1-1497) [endoplasmic reticulum lumen] (R-HSA-2172989) COL17A1(1-1497) [plasma membrane] (R-HSA-445994) COL17A1(1-1497) [endoplasmic reticulum lumen] (R-HSA-2172232) GlcGalHyl-COL17A1(1-1497) [plasma membrane] (R-HSA-2192833) GalHyl-COL17A1(1-1497) [plasma membrane] (R-HSA-2192832) 3x4Hyp-GalHyl-COL17A1(1-1497) [plasma membrane] (R-HSA-2192834) 3x4Hyp-3Hyp-GlcGalHyl-COL17A1(1-1497) [plasma membrane] (R-HSA-2192837) 3x4Hyp-COL17A1(1-1497) [plasma membrane] (R-HSA-2192836) 3x4Hyp-3Hyp-5Hyl-COL17A1(1-1497) [plasma membrane] (R-HSA-2192839) 3x4Hyp-5Hyl-COL17A1(1-1497) [plasma membrane] (R-HSA-2192841) 3x4Hyp-GlcGalHyl-COL17A1(1-1497) [plasma membrane] (R-HSA-2192840) 3x4Hyp-3Hyp-COL17A1(1-1497) [plasma membrane] (R-HSA-2192843) 5Hyl-COL17A1(1-1497) [plasma membrane] (R-HSA-2192842)	0.556	3
UniProt:O60306 AQR	1	AQR [nucleoplasm] (R-HSA-6781960)	0.528	2
UniProt:Q9Y315 DERA	4	DERA [cytosol] (R-HSA-6787324) DERA [ficolin-1-rich granule lumen] (R-HSA-6803295) DERA [extracellular region] (R-HSA-6806489) DERA [secretory granule lumen] (R-HSA-6803313)	0.527	2
UniProt:Q8N448 LNX2			0.488	2

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