Reactome | DDX42 [nucleoplasm]

DDX42 [nucleoplasm]

Stable Identifier

R-HSA-8867894

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

nucleoplasm

Synonyms

ATP-dependent RNA helicase DDX42 ecNumber3.6.4.13/ecNumber, DDX42_HUMAN

Locations in the PathwayBrowser

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External Reference Information

External Reference

UniProt:Q86XP3 DDX42

Gene Names

DDX42

Chain

chain:1-938

Reference Genes

BioGPS Gene:11325 DDX42

COSMIC (genes):DDX42 DDX42

CTD Gene:11325 DDX42

dbSNP Gene:11325 DDX42

ENSEMBL:ENSG00000198231 DDX42

ENSEMBL_homo_sapiens_GENE:ENSG00000198231.14 DDX42

HGNC:18676 DDX42

KEGG Gene (Homo sapiens):11325 DDX42

Monarch:11325 DDX42

NCBI Gene:11325 DDX42

OMIM:613369 DDX42

UCSC:Q86XP3 DDX42

Reference Transcript

Other Identifiers

11325

11727831_a_at

11727832_s_at

11757400_s_at

1559954_PM_s_at

1559954_s_at

16837004

201788_PM_at

201788_at

3730900

3730901

3730902

3730904

3730907

3730910

3730912

3730913

3730915

3730917

3730919

3730921

3730922

3730923

3730925

3730927

3730930

3730931

3730932

3730933

3730934

3730936

3730937

3730938

3730939

3730940

38762_at

8009205

A_14_P128394

A_24_P142531

GE54733

GO:0000166

GO:0003676

GO:0003723

GO:0003724

GO:0003824

GO:0004386

GO:0005515

GO:0005524

GO:0005634

GO:0005654

GO:0005737

GO:0005829

GO:0008104

GO:0012501

GO:0015030

GO:0016020

GO:0016071

GO:0016607

GO:0016787

GO:0016887

GO:0042981

GO:0043226

GO:0065003

GO:0071004

GO:0140098

GO:0140657

GO:1903241

HMNXSV003029645

Hs2.397166.1.S1_3p_s_at

ILMN_1674163

ILMN_1695983

PH_hs_0000927

TC17000771.hg

TC17002312.hg

g11321631_3p_at

Participates

as a component of

SF3B [nucleoplasm] (Homo sapiens)

Inferred To

Ghost homologue of DDX42 [nucleoplasm] (Bos taurus)

Ghost homologue of DDX42 [nucleoplasm] (Danio rerio)

Ghost homologue of DDX42 [nucleoplasm] (Plasmodium falciparum)

Ghost homologue of DDX42 [nucleoplasm] (Schizosaccharomyces pombe)

Ghost homologue of DDX42 [nucleoplasm] (Xenopus tropicalis)

Ddx42 [nucleoplasm] (Rattus norvegicus)

DmRH27 [nucleoplasm] (Drosophila melanogaster)

DDX42 [nucleoplasm] (Caenorhabditis elegans)

DDX42 [nucleoplasm] (Canis familiaris)

DDX42 [nucleoplasm] (Dictyostelium discoideum)

DDX42 [nucleoplasm] (Gallus gallus)

DDX42 [nucleoplasm] (Mus musculus)

DDX42 [nucleoplasm] (Sus scrofa)

Cross References

RefSeq

XP_016879600.1, XP_006721720.1, NP_031398.2, NP_987095.1

OpenTargets

ENSG00000198231

IntEnz

3.6.4.13

HPA

ENSG00000198231-DDX42

GeneCards

Q86XP3

Ensembl

ENSP00000374574, ENST00000578681, ENST00000389924, ENSP00000464050, ENST00000583590, ENSG00000198231, ENSP00000352308, ENSP00000463561, ENST00000359353

PRO

Q86XP3

Pharos - Targets

Q86XP3

HMDB Protein

HMDBP11675

PDB

7EVN, 8HK1, 8DPE

Interactors (2)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:O43143 DHX15	1	DHX15 [nucleoplasm] (R-HSA-5688097)	0.547	2
UniProt:P26368 U2AF2	2	5OHK15,276-U2AF2 [nucleoplasm] (R-HSA-9630011) U2AF2 [nucleoplasm] (R-HSA-71987)	0.483	2