TFPA2A homodimer and NPM1 bind the HSPD1 gene promoter

Stable Identifier
R-HSA-8869542
Type
Reaction [binding]
Species
Homo sapiens
Compartment
ReviewStatus
5/5
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In response to retinoic acid treatment, TFAP2A (AP-2 alpha) homodimers in complex with NPM1 (nucleophosmin) are recruited to the AP-2 alpha response element in the promoter of the mitochondrial chaperonin gene HSPD1 (Hsp60) (Liu et al. 2007).
Literature References
PubMed ID Title Journal Year
17318229 Nucleophosmin acts as a novel AP2alpha-binding transcriptional corepressor during cell differentiation

Yung, BY, Chuang, CP, Chen, KD, Tseng, KH, Tan, BC, Yeh, CW, Liu, H, Lee, SC

EMBO Rep. 2007
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