Toggle navigation
About
What is Reactome ?
News
Team
Scientific Advisory Board
Editorial Calendar
Release Calendar
Statistics
Our Logo
License Agreement
Privacy Notice
Disclaimer
Digital Preservation
Contact us
Content
Table of Contents
DOIs
Data Schema
Reactome Research Spotlight
ORCID Integration Project
COVID-19 Disease Pathways
Docs
Userguide
Pathway Browser
How do I search ?
Details Panel
Analysis Tools
Analysis Data
Analysis Gene Expression
Species Comparison
Tissue Distribution
Diseases
Cytomics
Review Status of Reactome Events
ReactomeFIViz
Developer's Zone
Graph Database
Analysis Service
Content Service
Pathways Overview
Pathway Diagrams
Icon Info
EHLD Specs & Guidelines
Icon Library Guidelines
Data Model
Computationally inferred events
FAQ
Linking to Us
Citing us
Tools
Pathway Browser
Analyse gene list
Analyse gene expression
Species Comparison
Tissue Distribution
Analysis Service
Content Service
ReactomeFIViz
Overlays
DisGeNET
Web
API
Advanced Data Search
Site Search
Community
Icon Library
Outreach
Events
Training
Publications
Partners
Contributors
Papers Citing Us
Resources Guide
Collaboration
Download
About
What is Reactome ?
News
Team
Scientific Advisory Board
Editorial Calendar
Release Calendar
Statistics
Our Logo
License Agreement
Privacy Notice
Disclaimer
Digital Preservation
Contact us
Content
Table of Contents
DOIs
Data Schema
Reactome Research Spotlight
ORCID Integration Project
COVID-19 Disease Pathways
Docs
Userguide
Pathway Browser
How do I search ?
Details Panel
Analysis Tools
Analysis Data
Analysis Gene Expression
Species Comparison
Tissue Distribution
Diseases
Cytomics
Review Status of Reactome Events
ReactomeFIViz
Developer's Zone
Graph Database
Analysis Service
Content Service
Pathways Overview
Pathway Diagrams
Icon Info
EHLD Specs & Guidelines
Icon Library Guidelines
Data Model
Computationally inferred events
FAQ
Linking to Us
Citing us
Tools
Pathway Browser
Analyse gene list
Analyse gene expression
Species Comparison
Tissue Distribution
Analysis Service
Content Service
ReactomeFIViz
Overlays
DisGeNET
Web
API
Advanced Data Search
Site Search
Community
Icon Library
Outreach
Events
Training
Publications
Partners
Contributors
Papers Citing Us
Resources Guide
Collaboration
Download
Search ...
Go!
RABGGTB [cytosol]
Stable Identifier
R-HSA-8870419
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
cytosol
Synonyms
Geranylgeranyl transferase type-2 subunit beta ecNumber2.5.1.60/ecNumber, PGTB2_HUMAN
Icon
Locations in the PathwayBrowser
Expand all
Metabolism of proteins (Homo sapiens)
Post-translational protein modification (Homo sapiens)
RAB geranylgeranylation (Homo sapiens)
FarC-PTP4A2 binds RABGGTB (Homo sapiens)
FarC-PTP4A2:RABGGTB [cytosol] (Homo sapiens)
RABGGTB [cytosol] (Homo sapiens)
RABGGTB [cytosol] (Homo sapiens)
RABGGTA and RABGGTB bind (Homo sapiens)
FarC-PTP4A2:RABGGTB [cytosol] (Homo sapiens)
RABGGTB [cytosol] (Homo sapiens)
RABGGTA:RABGGTB [cytosol] (Homo sapiens)
RABGGTB [cytosol] (Homo sapiens)
RABGGTB [cytosol] (Homo sapiens)
RGGT binds the RAB-binding subunit (Homo sapiens)
RABGGTA:RABGGTB [cytosol] (Homo sapiens)
RABGGTB [cytosol] (Homo sapiens)
RABGGTA:RABGGTB:CHMs:GGPP [cytosol] (Homo sapiens)
RABGGTA:RABGGTB [cytosol] (Homo sapiens)
RABGGTB [cytosol] (Homo sapiens)
RGGT geranylgeranylates RAB proteins (Homo sapiens)
RABGGTA:RABGGTB [cytosol] (Homo sapiens)
RABGGTB [cytosol] (Homo sapiens)
RGGT:CHMs:RABs:GDP [cytosol] (Homo sapiens)
RABGGTA:RABGGTB:CHMs:GGPP [cytosol] (Homo sapiens)
RABGGTA:RABGGTB [cytosol] (Homo sapiens)
RABGGTB [cytosol] (Homo sapiens)
RGGTA:RGGTB:GGPP [cytosol] (Homo sapiens)
RABGGTB [cytosol] (Homo sapiens)
RGGT:CHM binds RABs (Homo sapiens)
RABGGTA:RABGGTB:CHMs:GGPP [cytosol] (Homo sapiens)
RABGGTA:RABGGTB [cytosol] (Homo sapiens)
RABGGTB [cytosol] (Homo sapiens)
RGGT:CHMs:RABs:GDP [cytosol] (Homo sapiens)
RABGGTA:RABGGTB:CHMs:GGPP [cytosol] (Homo sapiens)
RABGGTA:RABGGTB [cytosol] (Homo sapiens)
RABGGTB [cytosol] (Homo sapiens)
External Reference Information
External Reference
UniProt:P53611 RABGGTB
Gene Names
RABGGTB, GGTB
Chain
initiator methionine:, chain:2-331
Reference Genes
BioGPS Gene:5876 RABGGTB
COSMIC (genes):RABGGTB RABGGTB
CTD Gene:5876 RABGGTB
dbSNP Gene:5876 RABGGTB
ENSEMBL:ENSG00000137955 RABGGTB
ENSEMBL_homo_sapiens_GENE:ENSG00000137955.16 RABGGTB
HGNC:9796 RABGGTB
KEGG Gene (Homo sapiens):5876 RABGGTB
Monarch:5876 RABGGTB
NCBI Gene:5876 RABGGTB
OMIM:179080 RABGGTB
Reference Transcript
RefSeq:NM_004582.3 RABGGTB
Other Identifiers
11724300_a_at
11757294_x_at
209180_PM_at
209180_at
209181_PM_s_at
209181_s_at
213704_PM_at
213704_at
2342633
2342637
2342638
2342639
2342640
2342644
2342649
2342650
2342652
2342656
2342658
2342659
2342660
2342662
37703_at
5876
781_at
7902382
A_14_P128168
A_23_P85371
A_24_P336705
A_33_P3311618
GO:0003824
GO:0004659
GO:0004663
GO:0005515
GO:0005829
GO:0005886
GO:0005968
GO:0007601
GO:0008270
GO:0008318
GO:0016740
GO:0018344
GO:0031267
GO:0036211
GO:0046872
GO:0050877
GO:0140096
HMNXSV003013751
ILMN_2163796
PH_hs_0004556
X98001_at
g1216503_3p_a_at
Participates
as an input of
FarC-PTP4A2 binds RABGGTB (Homo sapiens)
RABGGTA and RABGGTB bind (Homo sapiens)
as a component of
FarC-PTP4A2:RABGGTB [cytosol] (Homo sapiens)
RGGTA:RGGTB:GGPP [cytosol] (Homo sapiens)
RABGGTA:RABGGTB [cytosol] (Homo sapiens)
Other forms of this molecule
RABGGTB [plasma membrane]
Inferred To
RABGGTB [cytosol]
(Bos taurus)
RABGGTB [cytosol]
(Caenorhabditis elegans)
RABGGTB [cytosol]
(Canis familiaris)
RABGGTB [cytosol]
(Dictyostelium discoideum)
RABGGTB [cytosol]
(Gallus gallus)
RABGGTB [cytosol]
(Mus musculus)
RABGGTB [cytosol]
(Plasmodium falciparum)
RABGGTB [cytosol]
(Rattus norvegicus)
RABGGTB [cytosol]
(Saccharomyces cerevisiae)
RABGGTB [cytosol]
(Schizosaccharomyces pombe)
RabGGTb [cytosol]
(Drosophila melanogaster)
fj12b07 [cytosol]
(Danio rerio)
Ghost homologue of RABGGTB [cytosol]
(Sus scrofa)
Ghost homologue of RABGGTB [cytosol]
(Xenopus tropicalis)
Cross References
RefSeq
NP_004573.2
OpenTargets
ENSG00000137955
IntEnz
2.5.1.60
GeneCards
P53611
HPA
ENSG00000137955-RABGGTB
Ensembl
ENSP00000317473
,
ENST00000319942
,
ENSG00000137955
PRO
P53611
Pharos - Targets
P53611
HMDB Protein
HMDBP11879
PDB
6J7F
,
6J6X
,
6J7X
,
6O60
,
6J74
Interactors (8)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:Q9UBV7 B4GALT7
4
B4GALT7 A186D [Golgi membrane]
(R-HSA-3621785)
B4GALT7 L206P [Golgi membrane]
(R-HSA-3621790)
B4GALT7 R270C [Golgi membrane]
(R-HSA-3621734)
B4GALT7 [Golgi membrane]
(R-HSA-1889950)
0.718
6
UniProt:P57081 WDR4
1
WDR4 [nucleoplasm]
(R-HSA-6782341)
0.718
6
UniProt:Q92696 RABGGTA
2
RABGGTA [cytosol]
(R-HSA-8870418)
RABGGTA [plasma membrane]
(R-HSA-6801086)
0.666
4
UniProt:P20339 RAB5A
7
GGC-RAB5A [clathrin-coated endocytic vesicle membrane]
(R-HSA-8871125)
GGC-RAB5A [early endosome membrane]
(R-HSA-8875323)
GGC-RAB5A [cytosol]
(R-HSA-8870432)
RAB5A [cytosol]
(R-HSA-2201187)
GGC-RAB5A [macropinosome membrane]
(R-HSA-9837697)
RAB5A [endosome membrane]
(R-HSA-452257)
RAB5A [early endosome membrane]
(R-HSA-2130175)
0.569
3
UniProt:Q86YD3 TMM25
0.556
3
UniProt:P24592 IGFBP6
1
IGFBP6 [extracellular region]
(R-HSA-381475)
0.556
3
UniProt:Q7Z5A9 TAFA1
0.556
3
UniProt:Q96AX2 RAB37
5
GGC-RAB37 [cytosol]
(R-HSA-8873996)
RAB37 [cytosol]
(R-HSA-8873678)
RAB37 [azurophil granule membrane]
(R-HSA-6799607)
RAB37 [plasma membrane]
(R-HSA-6799686)
RAB37 [specific granule membrane]
(R-HSA-6799605)
0.488
2
© 2024
Reactome
Cite Us!
Cite Us!
Cite Us!
Warning!
Unable to extract citation. Please try again later.
Download As:
BibTeX
RIS
Text