APP gene expression

Stable Identifier
R-HSA-8870710
Type
Reaction [omitted]
Species
Homo sapiens
Compartment
ReviewStatus
5/5
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Transcription of the APP gene is increased by FOXO3, downstream of FOXO3 phosphorylation by aberrantly activated CDK5 (Shi et al. 2016).
Literature References
PubMed ID Title Journal Year
26962010 Cdk5-FOXO3a axis: initially neuroprotective, eventually neurodegenerative in Alzheimer's disease models

Viccaro, K, Shi, C, Lee, HG, Shah, K

J. Cell. Sci. 2016
Participants
Participates
This event is regulated
Disease
Name Identifier Synonyms
Alzheimer's disease DOID:10652 AD, Alzheimers dementia, Alzheimer disease
Authored
Created
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