Reactome | GGC-RAB5 [clathrin-coated endocytic vesicle membrane]

GGC-RAB5 [clathrin-coated endocytic vesicle membrane]

Stable Identifier

R-HSA-8871134

Type

Set [CandidateSet]

Species

Homo sapiens

Compartment

clathrin-coated endocytic vesicle membrane

Locations in the PathwayBrowser

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Vesicle-mediated transport (Homo sapiens)

- Membrane Trafficking (Homo sapiens)
  - Clathrin-mediated endocytosis (Homo sapiens)
    - Dissociation of AAK1 and dephosphorylation of AP-2 mu2 (Homo sapiens)
      - PI(4)P:p-T156 AP-2:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GDP:SYNJs:auxilin [clathrin-coated endocytic vesicle membrane] (Homo sapiens)
        
        GGC-RAB5:GDP:GAPVD1 [clathrin-coated endocytic vesicle membrane] (Homo sapiens)
        
        GGC-RAB5:GDP [clathrin-coated endocytic vesicle membrane] (Homo sapiens)
        
        GGC-RAB5 [clathrin-coated endocytic vesicle membrane] (Homo sapiens)
      - PI(4)P:p-T156 AP-2:ITSNs:EPS15:REPS1:SGIP1:NECAPs:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GDP:SYNJs:auxilinGGC-RAB5:GTP:GAPVD1 [clathrin-coated endocytic vesicle membrane] (Homo sapiens)
        
        GGC-RAB5:GTP:GAPVD1 [clathrin-coated endocytic vesicle membrane] (Homo sapiens)
        
        GGC-RAB5:GTP [clathrin-coated endocytic vesicle membrane] (Homo sapiens)
        
        GGC-RAB5 [clathrin-coated endocytic vesicle membrane] (Homo sapiens)
    - Dissociation of clathrin-associated proteins (Homo sapiens)
      - GGC-RAB5:GTP:GAPVD1 [clathrin-coated endocytic vesicle membrane] (Homo sapiens)
        
        GGC-RAB5:GTP [clathrin-coated endocytic vesicle membrane] (Homo sapiens)
        
        GGC-RAB5 [clathrin-coated endocytic vesicle membrane] (Homo sapiens)
      - PI(4)P:p-T156 AP-2:ITSNs:EPS15:REPS1:SGIP1:NECAPs:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GDP:SYNJs:auxilinGGC-RAB5:GTP:GAPVD1 [clathrin-coated endocytic vesicle membrane] (Homo sapiens)
        
        GGC-RAB5:GTP:GAPVD1 [clathrin-coated endocytic vesicle membrane] (Homo sapiens)
        
        GGC-RAB5:GTP [clathrin-coated endocytic vesicle membrane] (Homo sapiens)
        
        GGC-RAB5 [clathrin-coated endocytic vesicle membrane] (Homo sapiens)
    - RAB5 and GAPVD1 bind AP-2 (Homo sapiens)
      - GGC-RAB5:GDP:GAPVD1 [clathrin-coated endocytic vesicle membrane] (Homo sapiens)
        
        GGC-RAB5:GDP [clathrin-coated endocytic vesicle membrane] (Homo sapiens)
        
        GGC-RAB5 [clathrin-coated endocytic vesicle membrane] (Homo sapiens)
      - PI(4)P:p-T156 AP-2:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GDP:SYNJs:auxilin [clathrin-coated endocytic vesicle membrane] (Homo sapiens)
        
        GGC-RAB5:GDP:GAPVD1 [clathrin-coated endocytic vesicle membrane] (Homo sapiens)
        
        GGC-RAB5:GDP [clathrin-coated endocytic vesicle membrane] (Homo sapiens)
        
        GGC-RAB5 [clathrin-coated endocytic vesicle membrane] (Homo sapiens)

Participants

members

GGC-RAB5A [clathrin-coated endocytic vesicle membrane] (Homo sapiens)

candidates

Participates

as a component of

Inferred To

GGC-RAB5 [clathrin-coated endocytic vesicle membrane] (Bos taurus)

GGC-RAB5 [clathrin-coated endocytic vesicle membrane] (Canis familiaris)

GGC-RAB5 [clathrin-coated endocytic vesicle membrane] (Drosophila melanogaster)

GGC-RAB5 [clathrin-coated endocytic vesicle membrane] (Gallus gallus)

GGC-RAB5 [clathrin-coated endocytic vesicle membrane] (Mus musculus)

GGC-RAB5 [clathrin-coated endocytic vesicle membrane] (Rattus norvegicus)

GGC-RAB5 [clathrin-coated endocytic vesicle membrane] (Schizosaccharomyces pombe)

GGC-RAB5 [clathrin-coated endocytic vesicle membrane] (Sus scrofa)

rab-5 [clathrin-coated endocytic vesicle membrane] (Caenorhabditis elegans)