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ARHGEF40 [cytosol]
Stable Identifier
R-HSA-8873916
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
cytosol
Synonyms
Rho guanine nucleotide exchange factor 40, ARH40_HUMAN, Scambio
Locations in the PathwayBrowser
Expand all
Signal Transduction (Homo sapiens)
Death Receptor Signaling (Homo sapiens)
p75 NTR receptor-mediated signalling (Homo sapiens)
Cell death signalling via NRAGE, NRIF and NADE (Homo sapiens)
NRAGE signals death through JNK (Homo sapiens)
p75NTR indirectly activates RAC and Cdc42 via a guanyl-nucleotide exchange factor (Homo sapiens)
GEFs [cytosol] (Homo sapiens)
ARHGEF40 [cytosol] (Homo sapiens)
Signaling by GPCR (Homo sapiens)
GPCR downstream signalling (Homo sapiens)
G alpha (12/13) signalling events (Homo sapiens)
GEFs activate RhoA,B,C (Homo sapiens)
GEFs [cytosol] (Homo sapiens)
ARHGEF40 [cytosol] (Homo sapiens)
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 (Homo sapiens)
Signaling by Rho GTPases (Homo sapiens)
RHO GTPase cycle (Homo sapiens)
RHOA GTPase cycle (Homo sapiens)
RHOA GEFs activate RHOA (Homo sapiens)
RHOA GEFs [cytosol] (Homo sapiens)
ARHGEF40 [cytosol] (Homo sapiens)
RHOC GTPase cycle (Homo sapiens)
RHOC GEFs activate RHOC (Homo sapiens)
RHOC GEFs [cytosol] (Homo sapiens)
ARHGEF40 [cytosol] (Homo sapiens)
External Reference Information
External Reference
UniProt:Q8TER5 ARHGEF40
Gene Names
ARHGEF40, SOLO
Chain
chain:1-1519
Reference Genes
BioGPS Gene:55701 ARHGEF40
COSMIC (genes):ARHGEF40 ARHGEF40
CTD Gene:55701 ARHGEF40
dbSNP Gene:55701 ARHGEF40
ENSEMBL:ENSG00000165801 ARHGEF40
ENSEMBL_homo_sapiens_GENE:ENSG00000165801.10 ARHGEF40
HGNC:25516 ARHGEF40
KEGG Gene (Homo sapiens):55701 ARHGEF40
Monarch:55701 ARHGEF40
NCBI Gene:55701 ARHGEF40
OMIM:610018 ARHGEF40
UCSC:Q8TER5 ARHGEF40
Reference Transcript
RefSeq:NM_018071.4 ARHGEF40
RefSeq:XM_005267844.2 ARHGEF40
RefSeq:NM_001278529.1 ARHGEF40
Other Identifiers
11755297_a_at
11759487_at
16781695
16781729
220326_3p_s_at
220326_PM_s_at
220326_s_at
227855_PM_at
227855_at
3527860
3527863
3527865
3527866
3527867
3527868
3527869
3527870
3527871
3527872
3527873
3527874
3527875
3527876
3527877
3527878
3527879
3527880
3527881
3527882
3527883
3527884
3527885
3527886
3527887
3527888
3527889
3527890
3527891
3527892
3527893
3527894
3527895
3527929
3527931
3527933
55701
57907_at
57912_g_at
58780_PM_s_at
58780_s_at
7973158
A_23_P99661
GE56674
GO:0005085
GO:0005737
GO:0005829
GO:0005886
GO:0007411
GO:0019898
GO:0023052
GO:0030154
GO:0048856
GO:0051056
GO:0098772
HMNXSV003041994
HMNXSV003050673
Hs.250493.1.A1_3p_at
ILMN_1705743
PH_hs_0001961
PH_hs_0031065
TC14000082.hg
g8922375_3p_a_at
g8922375_3p_s_at
g8922375_3p_x_at
p4736
Participates
as a candidate of
RHOA GEFs [cytosol] (Homo sapiens)
GEFs [cytosol] (Homo sapiens)
as a member of
RHOC GEFs [cytosol] (Homo sapiens)
Inferred To
Dmel\CG15611 [cytosol]
(Drosophila melanogaster)
CG15612 [cytosol]
(Drosophila melanogaster)
trio [cytosol]
(Drosophila melanogaster)
Arhgef25 [cytosol]
(Mus musculus)
Arhgef25 [cytosol]
(Rattus norvegicus)
ARHGEF25 [cytosol]
(Bos taurus)
ARHGEF25 [cytosol]
(Canis familiaris)
ARHGEF25 [cytosol]
(Sus scrofa)
Homologues of ARHGEF40 [cytosol]
(Drosophila melanogaster)
unc-73 [cytosol]
(Caenorhabditis elegans)
arhgef25 [cytosol]
(Xenopus tropicalis)
Cross References
RefSeq
NP_001265458.1
,
XP_005267901.1
,
NP_060541.3
OpenTargets
ENSG00000165801
HPA
ENSG00000165801-ARHGEF40
GeneCards
Q8TER5
Ensembl
ENSG00000165801
,
ENST00000298694
,
ENSP00000298694
PRO
Q8TER5
Pharos - Targets
Q8TER5
HMDB Protein
HMDBP11491
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