TFAP2C homodimer binds the EGFR gene promoter

Stable Identifier
R-HSA-8874789
Type
Reaction [binding]
Species
Homo sapiens
Compartment
nucleoplasm
ReviewStatus
5/5
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TFAP2C homodimer binds the EGFR gene promoter
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TFAP2C (AP-2 gamma) homodimer binds the promoter region of the EGFR gene (Park et al. 2015, De Andrade et al. 2016).
Literature References
PubMed ID Title Journal Year
26832794 EGFR Is Regulated by TFAP2C in Luminal Breast Cancer and Is a Target for Vandetanib

Lorenzen, AW, Spanheimer, PM, Weigel, RJ, Van Dorin, SE, Park, JM, Kulak, MV, Wu, VT, De Andrade, JP, Gu, VW, Woodfield, GW

Mol. Cancer Ther. 2016
25772240 The role of Tcfap2c in tumorigenesis and cancer growth in an activated Neu model of mammary carcinogenesis

Lal, G, Woodfield, GW, Wu, T, De Andrade, JP, Spanheimer, PM, Zhang, W, Sugg, SL, Li, T, Park, JM, Weigel, RJ, Cyr, AR, Domann, FE

Oncogene 2015
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Authored
Orlic-Milacic, M  (2016-03-14)
Reviewed
Bogachek, MV  (2016-05-17)
Weigel, RJ  (2016-05-17)
Created
Orlic-Milacic, M  (2016-05-27)
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