Reactome | ACBD3 [Golgi membrane]

ACBD3 [Golgi membrane]

Stable Identifier

R-HSA-8874981

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

Golgi membrane

Synonyms

Golgi resident protein GCP60, GCP60_HUMAN

Locations in the PathwayBrowser

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External Reference Information

External Reference

UniProt:Q9H3P7 ACBD3

Gene Names

ACBD3, GCP60, GOCAP1, GOLPH1

Chain

chain:1-528, initiator methionine:, chain:2-528

Reference Genes

BioGPS Gene:64746 ACBD3

COSMIC (genes):ACBD3 ACBD3

CTD Gene:64746 ACBD3

dbSNP Gene:64746 ACBD3

ENSEMBL:ENSG00000182827 ACBD3

HGNC:15453 ACBD3

Monarch:64746 ACBD3

NCBI Gene:64746 ACBD3

OMIM:606809 ACBD3

UCSC:Q9H3P7 ACBD3

Reference Transcript

RefSeq:NM_022735.3 ACBD3

Other Identifiers

11743566_at

11743567_s_at

16700023

202323_PM_s_at

202323_s_at

202324_PM_s_at

202324_s_at

2458702

2458703

2458704

2458705

2458706

2458707

2458710

2458711

2458712

2458714

2458715

2458716

2458717

2458718

2458721

2458722

2458723

2458724

2458725

2458726

36827_at

64746

7924701

89155_at

A_24_P171182

GE54163

GO:0000062

GO:0000139

GO:0005515

GO:0005739

GO:0005794

GO:0006629

GO:0006694

GO:0008289

GO:0016020

GO:0034237

GO:0043226

HMNXSV003054822

Hs.6831.0.S1_3p_a_at

ILMN_1665945

PH_hs_0000692

TC01003897.hg

g12232390_3p_a_at

Participates

as a component of

ACBD3:GOLGB1 dimer [Golgi membrane] (Homo sapiens)

as an input of

ACBD3 binds GOLGB1 (Homo sapiens)

Inferred To

Acbd3 [Golgi membrane] (Mus musculus)

Acbd3 [Golgi membrane] (Rattus norvegicus)

tmed8 [Golgi membrane] (Xenopus tropicalis)

ACBD3 [Golgi membrane] (Bos taurus)

ACBD3 [Golgi membrane] (Caenorhabditis elegans)

ACBD3 [Golgi membrane] (Canis familiaris)

ACBD3 [Golgi membrane] (Gallus gallus)

ACBD3 [Golgi membrane] (Sus scrofa)

anon-18DEc [Golgi membrane] (Drosophila melanogaster)

cb366 [Golgi membrane] (Danio rerio)

Cross References

ENSEMBL

ENST00000366812, ENSP00000355777

OpenTargets

ENSG00000182827

HPA

ENSG00000182827-ACBD3

PRO

Q9H3P7

Pharos - Targets

Q9H3P7

GlyGen

Q9H3P7

HMDB Protein

HMDBP11373

PDB

5LZ6, 6HMV, 6HLT, 6HM8, 5TDQ, 6HLW, 6HLN, 5LZ1, 6HLV, 2N73, 5LZ3, 2N72

Interactors (14)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:Q9NU19 TB22B			0.744	7
UniProt:O91464 POLG			0.737	13
UniProt:Q8WUA7 TB22A			0.725	15
UniProt:O91464-PRO_0000448012			0.593	4
UniProt:O91464-PRO_0000448015			0.593	5
UniProt:O91464-PRO_0000448014			0.593	5
UniProt:A0A0B4J1S8 A0A0B4J1S8			0.567	6
UniProt:P03300-PRO_0000424692			0.567	12
UniProt:O43493 TGOLN2	8	TGOLN2 [clathrin-coated endocytic vesicle membrane] (R-HSA-8869127) TGOLN2 [plasma membrane] (R-HSA-8864458) TGOLN2 [Golgi membrane] (R-HSA-434342) TGOLN2 [cytoplasmic vesicle membrane] (R-HSA-429818) TGOLN2 [trans-Golgi network membrane] (R-HSA-6811008) TGOLN2 [transport vesicle] (R-HSA-6811011) p-TGOLN2 [endoplasmic reticulum lumen] (R-HSA-8956886) TGOLN2 [endoplasmic reticulum lumen] (R-HSA-8956702)	0.548	5
UniProt:Q8BHN0	1	PPM1L [endoplasmic reticulum membrane] (R-MMU-429688)	0.543	3
UniProt:Q9UBF8 PI4KB	2	PI4KB [Golgi membrane] (R-HSA-1806202) PI4KB [cytosol] (R-HSA-1604615)	0.543	4
UniProt:Q6PJG9 LRFN4	1	SALM3 [plasma membrane] (R-HSA-197883)	0.527	2
UniProt:Q66282-PRO_0000039600			0.508	2
UniProt:P04578 env	7	ENV [viral envelope] (R-HIV-173439) Surface protein gp120 [viral envelope] (R-HIV-171211) Transmembrane protein gp41 [viral envelope] (R-HIV-171195) Envelope glycoprotein gp160 [endoplasmic reticulum membrane] (R-HIV-189343) Glycosylated Envelope glycoprotein gp160 [Golgi membrane] (R-HIV-3149443) Transmembrane protein gp41 (P04578) [cytosol] (R-HIV-189359) Surface protein gp120 (P04578) [cytosol] (R-HIV-189269)	0.462	2

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