RUNX1 and NFATC2 bind the IL2 gene promoter

Stable Identifier
R-HSA-8877338
Type
Reaction [binding]
Species
Homo sapiens
Compartment
ReviewStatus
5/5
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The complex of CBFB and RUNX1 (AML1) binds to the promoter of the IL2 gene in cooperation with NFATC2 (NFAT1). NFAT response element is adjacent to RUNX1 response element in the IL2 promoter (Ono et al. 2007).
Literature References
PubMed ID Title Journal Year
17377532 Foxp3 controls regulatory T-cell function by interacting with AML1/Runx1

Nagamura, Y, Ono, M, Kitabayashi, I, Tsukada, T, Ohkura, N, Sakaguchi, S, Nomura, T, Yaguchi, H, Miyachi, Y

Nature 2007
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