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Me2aR-RPS2 [cytosol]
Stable Identifier
R-HSA-8879138
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
cytosol
Synonyms
40S small ribosomal protein 2, P15880, 40S ribosomal protein S2, S4, LLREP3 protein
Icon
Locations in the PathwayBrowser
Expand all
Chromatin organization (Homo sapiens)
Chromatin modifying enzymes (Homo sapiens)
RMTs methylate histone arginines (Homo sapiens)
PRMT3 transfers 3xCH3 from 3xAdoMet to RPS2 (Homo sapiens)
Me2aR-RPS2 [cytosol] (Homo sapiens)
Metabolism of proteins (Homo sapiens)
Post-translational protein modification (Homo sapiens)
Protein methylation (Homo sapiens)
PRMT3 transfers 3xCH3 from 3xAdoMet to RPS2 (Homo sapiens)
Me2aR-RPS2 [cytosol] (Homo sapiens)
External Reference Information
External Reference
UniProt:P15880 RPS2
Gene Names
RPS2, RPS4
Chain
initiator methionine:1, chain:2-293
Reference Genes
BioGPS Gene:6187 RPS2
COSMIC (genes):RPS2 RPS2
CTD Gene:6187 RPS2
dbSNP Gene:6187 RPS2
ENSEMBL:ENSG00000140988.16 RPS2
HGNC:10404 RPS2
KEGG Gene (Homo sapiens):6187 RPS2
Monarch:6187 RPS2
NCBI Gene:6187 RPS2
OMIM:603624 RPS2
UCSC:P15880 RPS2
Reference Transcript
RefSeq:NM_002952.3 RPS2
Other Identifiers
0000870035
11756061_x_at
16822889
16822913
16822917
203107_3p_x_at
203107_PM_x_at
203107_x_at
212433_PM_x_at
212433_x_at
217466_PM_x_at
217466_x_at
221798_3p_x_at
221798_PM_x_at
221798_x_at
2331692
2331695
2335812
2363662
2373983
2414433
2475662
2491307
2785960
2785961
2787747
2907930
2954754
2954763
31527_at
3322248
3433833
3433834
3433835
3433836
3433837
3433838
3433839
3571878
3581198
3606530
3676302
3676303
3676304
3676308
3676309
3676310
3676313
3676318
3676322
3676324
3748826
3748828
3748829
3748830
3748831
3748832
3748833
3748834
3748836
3763019
3882787
3907385
3907388
4005753
4005754
6187
72997_f_at
7998655
8013348
8172154
89980_s_at
GO:0002181
GO:0003723
GO:0003729
GO:0003735
GO:0005198
GO:0005515
GO:0005576
GO:0005615
GO:0005622
GO:0005634
GO:0005654
GO:0005737
GO:0005829
GO:0005840
GO:0005925
GO:0006412
GO:0015935
GO:0016020
GO:0017134
GO:0019899
GO:0022626
GO:0022627
GO:0032991
GO:0036211
GO:0043226
GO:0045296
GO:0051443
GO:0070062
GO:1990904
HMNXSV003024132
Hs.182426.2.S1_3p_x_at
Hs.182426.3.A1_3p_a_at
Hs.182426.4.A1_3p_a_at
ILMN_1688749
ILMN_1737074
ILMN_2133360
ILMN_2218277
PH_hs_0030566
PH_hs_0039080
TC16000768.hg
TC17002540.hg
X17206_at
g4506718_3p_a_at
g4506718_3p_x_at
Participates
as an output of
PRMT3 transfers 3xCH3 from 3xAdoMet to RPS2 (Homo sapiens)
Other forms of this molecule
RPS2 [nucleoplasm]
RPS2 [cytosol]
Inferred To
Me2aR-RPS2 [cytosol]
(Bos taurus)
Me2aR-RPS2 [cytosol]
(Canis familiaris)
Me2aR-RPS2 [cytosol]
(Danio rerio)
Me2aR-RPS2 [cytosol]
(Plasmodium falciparum)
Rps2 [cytosol]
(Mus musculus)
rps-2 [cytosol]
(Caenorhabditis elegans)
RPS2 [cytosol]
(Gallus gallus)
RPS2 [cytosol]
(Saccharomyces cerevisiae)
RPS2 [cytosol]
(Sus scrofa)
RpS2 [cytosol]
(Drosophila melanogaster)
rps2 [cytosol]
(Dictyostelium discoideum)
rps2 [cytosol]
(Schizosaccharomyces pombe)
rps2 [cytosol]
(Xenopus tropicalis)
Rps2-ps6 [cytosol]
(Rattus norvegicus)
Modified Residues
Name
asymmetric dimethyl-L-arginine at unknown position
PsiMod Name
asymmetric dimethyl-L-arginine
PsiMod Definition
A protein modification that effectively converts an L-arginine residue to asymmetric dimethylarginine, N(omega),N(omega)-dimethyl-L-arginine.
Cross References
RefSeq
NP_002943.2
OpenTargets
ENSG00000140988
HPA
ENSG00000140988-RPS2
GeneCards
P15880
Ensembl
ENSG00000140988
,
ENST00000343262
,
ENSP00000341885
PRO
P15880
Pharos - Targets
P15880
PDB
6ZV6
,
6IP8
,
6Y0G
,
6YBD
,
6ZP4
,
5A2Q
,
5AJ0
,
6Y57
,
6G51
,
6YBW
,
6ZXG
,
6G53
,
7JQB
,
6ZXD
,
6ZM7
,
6ZN5
,
6ZVH
,
7K5I
,
6ZLW
,
5OA3
,
6ZME
,
6ZXE
,
7JQC
,
6ZUO
,
6ZVJ
,
5T2C
,
6OLG
,
6XA1
,
5LKS
,
6OLF
,
6ZMI
,
6Y2L
,
6G5I
,
6QZP
,
6ZXF
,
6OLI
,
6IP6
,
6IP5
,
6G5H
,
5FLX
,
4UG0
,
6OM7
,
6ZMO
,
6OLZ
,
7A09
,
6OM0
,
6OLE
,
6ZOK
,
6ZMW
,
5VYC
,
6ZOJ
,
6Z6M
,
6G4S
,
6G18
,
6ZXH
,
6ZMT
,
6Z6L
,
4V6X
,
6ZON
,
6Z6N
Interactors (8)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:O60678 PRMT3
1
PRMT3 [cytosol]
(R-HSA-8876692)
0.75
5
UniProt:Q5S007 LRRK2
1
LRRK2 [cytosol]
(R-HSA-5661173)
0.642
4
UniProt:Q9H0A0 NAT10
1
NAT10 [nucleoplasm]
(R-HSA-6791008)
0.564
2
UniProt:P60520 GABARAPL2
3
GABARAPL2 [autophagosome membrane]
(R-HSA-5683633)
GABARAPL2(1-117) [cytosol]
(R-HSA-5682641)
GABARAPL2 [cytosol]
(R-HSA-5671758)
0.547
2
UniProt:P0DTD1-PRO_0000449619 REP
0.528
3
UniProt:P19320 VCAM1
1
VCAM1 [plasma membrane]
(R-HSA-197834)
0.527
4
UniProt:P63244 RACK1
1
GNB2L1 [cytosol]
(R-HSA-5626956)
0.495
2
UniProt:P03372 ESR1
8
p-S118-ESR1 [nucleoplasm]
(R-HSA-9024210)
monoSUMO1-5K-ESR1 [nucleoplasm]
(R-HSA-4090302)
Me260-PalmS-ESR1 [plasma membrane]
(R-HSA-9637788)
PalmS-ESR1 [plasma membrane]
(R-HSA-9021057)
PalmS-ESR1 [cytosol]
(R-HSA-9020974)
Me260-ESR1 [cytosol]
(R-HSA-9632177)
ESR1 [nucleoplasm]
(R-HSA-446168)
ESR1 [cytosol]
(R-HSA-9020968)
0.462
2
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