Reactome | PNRC2 [cytosol]

PNRC2 [cytosol]

Stable Identifier

R-HSA-8879146

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

cytosol

Synonyms

Proline-rich nuclear receptor coactivator 2, PNRC2_HUMAN

Locations in the PathwayBrowser for interactor UniProt:Q8IU60 DCP2

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External Reference Information

External Reference

UniProt:Q9NPJ4 PNRC2

Gene Names

PNRC2, HSPC208

Chain

chain:1-139

Reference Genes

BioGPS Gene:55629 PNRC2

COSMIC (genes):PNRC2 PNRC2

CTD Gene:55629 PNRC2

dbSNP Gene:55629 PNRC2

ENSEMBL:ENSG00000189266 PNRC2

HGNC:23158 PNRC2

KEGG:hsa:55629 PNRC2

Monarch:55629 PNRC2

NCBI Gene:55629 PNRC2

OMIM:611882 PNRC2

UCSC:Q9NPJ4 PNRC2

Reference Transcript

Participates

as an input of

p-4S-UPF1 recruits SMG5, SMG7, SMG6, PNRC2, DCP1A, and PP2A (Homo sapiens)

Inferred To

pnrc2 [cytosol] (Danio rerio)

pnrc2 [cytosol] (Xenopus tropicalis)

Pnrc2 [cytosol] (Mus musculus)

Pnrc2 [cytosol] (Rattus norvegicus)

PNRC2 [cytosol] (Bos taurus)

PNRC2 [cytosol] (Canis familiaris)

PNRC2 [cytosol] (Sus scrofa)

Cross References

ENSEMBL

ENSP00000363592, ENSP00000334840, ENST00000374468, ENST00000647887, ENST00000334351, ENSG00000189266, ENSP00000497590

OpenTargets

ENSG00000189266

GeneCards

PNRC2

HPA

ENSG00000189266-PNRC2

PRO

Q9NPJ4

Pharos - Targets

Q9NPJ4

PDB

5KQ1, 5KQ4, 4B6H

Interactors (8)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:Q9NPI6 DCP1A	1	DCP1A [cytosol] (R-HSA-430043)	0.91	12
UniProt:Q92900 UPF1	2	UPF1 [cytosol] (R-HSA-927734) p-4S-UPF1 [cytosol] (R-HSA-927856)	0.616	9
UniProt:P62508-3 ESRRG			0.556	3
UniProt:P51570 GALK1	6	GALK1 [cytosol] (R-HSA-70353) GALK1 Q382* [cytosol] (R-HSA-5610007) GALK1 E80* [cytosol] (R-HSA-5610003) GALK1 P28T [cytosol] (R-HSA-5610013) GALK1 R256W [cytosol] (R-HSA-5610012) GALK1 V32M [cytosol] (R-HSA-5610010)	0.556	3
UniProt:Q8N9N5-2 BANP			0.556	3
UniProt:Q8IU60 DCP2	1	DCP2 [cytosol] (R-HSA-429937)	0.527	2
UniProt:Q13285 NR5A1	3	NR5A1 [nucleoplasm] (R-HSA-452955) polySUMO2-K119,K194-NR5A1 [nucleoplasm] (R-HSA-4546383) monoSUMO1-K119,K194-NR5A1 [nucleoplasm] (R-HSA-4546382)	0.488	2
UniProt:P03372 ESR1	10	ESR1 [cytosol] (R-HSA-9020968) ESR1 [nucleoplasm] (R-HSA-446168) Me260-PalmS-ESR1 [plasma membrane] (R-HSA-9637788) PalmS-ESR1 [plasma membrane] (R-HSA-9021057) PalmS-ESR1 [cytosol] (R-HSA-9020974) Me260-ESR1 [cytosol] (R-HSA-9632177) p-S167-ESR1 [cytosol] (R-HSA-9841254) p-S167-ESR1 [nucleoplasm] (R-HSA-9841867) monoSUMO1-5K-ESR1 [nucleoplasm] (R-HSA-4090302) p-S118-ESR1 [nucleoplasm] (R-HSA-9024210)	0.488	2

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