RUNX1 and ESR1 bind the GPAM gene enhancer

Stable Identifier
R-HSA-8932021
Type
Reaction [binding]
Species
Homo sapiens
Compartment
ReviewStatus
5/5
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RUNX1 and ESR1 cooperatively bind to the enhancer of the GPAM gene, which contains both estrogen response elements and RUNX1 binding sites (Stender et al. 2010).
Literature References
PubMed ID Title Journal Year
20547749 Genome-wide analysis of estrogen receptor alpha DNA binding and tethering mechanisms identifies Runx1 as a novel tethering factor in receptor-mediated transcriptional activation

Kraus, WL, Stender, JD, Benner, C, Charn, TH, Kim, K, Chang, KC, Katzenellenbogen, BS, Glass, CK, Komm, B

Mol. Cell. Biol. 2010
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