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RWDD3 [nucleoplasm]
Stable Identifier
R-HSA-8932136
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
nucleoplasm
Synonyms
RWD domain-containing protein 3, RWDD3_HUMAN
Locations in the PathwayBrowser
Expand all
Metabolism of proteins (Homo sapiens)
Post-translational protein modification (Homo sapiens)
SUMOylation (Homo sapiens)
Processing and activation of SUMO (Homo sapiens)
SUMO is transferred from E1 to E2 (UBE2I, UBC9) (Homo sapiens)
Transfer of SUMO1 from E1 to UBE2I (UBC9) (Homo sapiens)
RWDD3 [nucleoplasm] (Homo sapiens)
External Reference Information
External Reference
UniProt:Q9Y3V2 RWDD3
Gene Names
RWDD3, RSUME
Chain
chain:1-267
Reference Genes
BioGPS Gene:25950 RWDD3
COSMIC (genes):RWDD3 RWDD3
CTD Gene:25950 RWDD3
dbSNP Gene:25950 RWDD3
ENSEMBL:ENSG00000122481 RWDD3
ENSEMBL_homo_sapiens_GENE:ENSG00000122481.17 RWDD3
HGNC:21393 RWDD3
KEGG Gene (Homo sapiens):25950 RWDD3
Monarch:25950 RWDD3
NCBI Gene:25950 RWDD3
OMIM:615875 RWDD3
UCSC:Q9Y3V2 RWDD3
Reference Transcript
RefSeq:NM_001128142.1 RWDD3
RefSeq:NM_001278248.1 RWDD3
RefSeq:NM_001278247.1 RWDD3
Other Identifiers
11725901_x_at
11740883_a_at
205087_PM_at
205087_at
2347791
2347792
2347805
2347806
2347807
2347808
2347811
2347813
2347814
2347815
2347816
25950
33776_at
7903171
A_14_P126646
A_21_P0000145
A_23_P933
GE82010
GO:0005515
GO:0005634
GO:0005737
GO:0006351
GO:0006355
GO:0023052
GO:0032088
GO:0033235
GO:0036211
GO:0043226
GO:1902073
HMNXSV003051023
HMNXSV003053242
ILMN_1796835
PH_hs_0035683
TC01004548.hg
g7661655_3p_at
This entity regulates
Positively
Transfer of SUMO1 from E1 to UBE2I (UBC9)
(Homo sapiens)
Inferred To
RWDD3 [nucleoplasm]
(Gallus gallus)
RWDD3 [nucleoplasm]
(Rattus norvegicus)
rwdd2b [nucleoplasm]
(Danio rerio)
rwdd2b [nucleoplasm]
(Xenopus tropicalis)
RWDD2B [nucleoplasm]
(Bos taurus)
RWDD2B [nucleoplasm]
(Sus scrofa)
Rwdd2b [nucleoplasm]
(Mus musculus)
Cross References
RefSeq
NP_001121614.1
,
NP_001265176.1
,
NP_001265177.1
OpenTargets
ENSG00000122481
GeneCards
Q9Y3V2
HPA
ENSG00000122481-RWDD3
Ensembl
ENSP00000263893
,
ENST00000370202
,
ENSG00000122481
,
ENSP00000359221
,
ENST00000263893
PRO
Q9Y3V2
Pharos - Targets
Q9Y3V2
PDB
4Y1L
,
2EBK
Interactors (1)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:P63279 UBE2I
9
monoSUMO1-K14-UBE2I [nucleoplasm]
(R-HSA-4085358)
UBE2I [nuclear envelope]
(R-HSA-4655408)
SUMO2-C93-UBE2I [cytosol]
(R-HSA-4656944)
SUMO3-C93-UBE2I [nucleoplasm]
(R-HSA-3730629)
UBE2I [cytosol]
(R-HSA-4655342)
SUMO1-C93-UBE2I [cytosol]
(R-HSA-4656909)
SUMO2-C93-UBE2I [nucleoplasm]
(R-HSA-3730619)
SUMO1-C93-UBE2I [nucleoplasm]
(R-HSA-3730617)
UBE2I [nucleoplasm]
(R-HSA-912481)
0.61
5
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