METTL10 transfers 3xCH3 from 3xAdoMet to EEF1A1

Stable Identifier
R-HSA-8932413
Type
Reaction [transition]
Species
Homo sapiens
Compartment
cytosol
ReviewStatus
5/5
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METTL10 transfers 3xCH3 from 3xAdoMet to EEF1A1
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Protein-lysine N-methyltransferase METTL10 trimethylates Elongation factor 1-alpha 1 (EF1A1) at lysine-318 (Shimazu et al. 2014).
Literature References
PubMed ID Title Journal Year
25144183 Selenium-based S-adenosylmethionine analog reveals the mammalian seven-beta-strand methyltransferase METTL10 to be an EF1A1 lysine methyltransferase

Shinkai, Y, Sodeoka, M, Sohtome, Y, Barjau, J, Shimazu, T

PLoS ONE 2014
Participants
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Output
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as an event of
Catalyst Activity

protein-lysine N-methyltransferase activity of METTL10 [cytosol]

Physical Entity
METTL10 [cytosol] (Homo sapiens)
Activity
protein-lysine N-methyltransferase activity (GO:0016279)
Orthologous Events
METTL10 transfers 3xCH3 from 3xAdoMet to EEF1A1 (Bos taurus)
METTL10 transfers 3xCH3 from 3xAdoMet to EEF1A1 (Caenorhabditis elegans)
METTL10 transfers 3xCH3 from 3xAdoMet to EEF1A1 (Canis familiaris)
METTL10 transfers 3xCH3 from 3xAdoMet to EEF1A1 (Danio rerio)
METTL10 transfers 3xCH3 from 3xAdoMet to EEF1A1 (Dictyostelium discoideum)
METTL10 transfers 3xCH3 from 3xAdoMet to EEF1A1 (Drosophila melanogaster)
METTL10 transfers 3xCH3 from 3xAdoMet to EEF1A1 (Gallus gallus)
METTL10 transfers 3xCH3 from 3xAdoMet to EEF1A1 (Mus musculus)
METTL10 transfers 3xCH3 from 3xAdoMet to EEF1A1 (Plasmodium falciparum)
METTL10 transfers 3xCH3 from 3xAdoMet to EEF1A1 (Saccharomyces cerevisiae)
METTL10 transfers 3xCH3 from 3xAdoMet to EEF1A1 (Schizosaccharomyces pombe)
METTL10 transfers 3xCH3 from 3xAdoMet to EEF1A1 (Sus scrofa)
Authored
Jupe, S  (2016-06-16)
Reviewed
Falnes, PØ  (2016-10-10)
Created
Jupe, S  (2016-07-25)
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