RUNX1 binds the CLDN5 (Claudin-5) gene promoter

Stable Identifier
R-HSA-8936000
Type
Reaction [binding]
Species
Homo sapiens
Compartment
nucleoplasm
ReviewStatus
5/5
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RUNX1 binds the CLDN5 (Claudin-5) gene promoter
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The RUNX1:CBFB complex binds the promoter of the CLDN5 gene, encoding the component of tight junctions Claudin-5 (Miao et al. 2015).
Literature References
PubMed ID Title Journal Year
25452107 MiR-18a increased the permeability of BTB via RUNX1 mediated down-regulation of ZO-1, occludin and claudin-5

Xue, YX, Wang, P, Zhao, YY, Miao, YS, Ma, J, Liu, YH, Zhao, LN

Cell. Signal. 2015
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Authored
Orlic-Milacic, M  (2016-09-14)
Reviewed
Chuang, LS  (2016-12-20)
Ito, Y  (2016-12-20)
Created
Orlic-Milacic, M  (2016-08-16)
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